Search Results - "Jun-Won Yun"

Human Umbilical Cord Blood Mesenchymal Stem Cell‐Derived PGE2 and TGF‐β1 Alleviate Atopic Dermatitis by Reducing Mast Cell Degranulation by Kim, Hyung‐Sik, Yun, Jun‐Won, Shin, Tae‐Hoon, Lee, Sung‐Hoon, Lee, Byung‐Chul, Yu, Kyung‐Rok, Seo, Yoojin, Lee, Seunghee, Kang, Tae‐Wook, Choi, Soon Won, Seo, Kwang‐Won, Kang, Kyung‐Sun

“…Mesenchymal stem cell (MSC) is a promising tool for the therapy of immune disorders. However, their efficacy and mechanisms in treating allergic skin disorders…”
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CYP2E1 potentiates binge alcohol-induced gut leakiness, steatohepatitis, and apoptosis by Abdelmegeed, Mohamed A, Banerjee, Atrayee, Jang, Sehwan, Yoo, Seong-Ho, Yun, Jun-Won, Gonzalez, Frank J, Keshavarzian, Ali, Song, Byoung-Joon

“…Ethanol-inducible cytochrome P450 2E1 (CYP2E1) contributes to increased oxidative stress and steatosis in chronic alcohol-exposure models. However, its role in…”
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Comparative toxicity of silicon dioxide, silver and iron oxide nanoparticles after repeated oral administration to rats by Yun, Jun-Won, Kim, Seung-Hyun, You, Ji-Ran, Kim, Woo Ho, Jang, Ja-June, Min, Seung-Kee, Kim, Hee Chan, Chung, Doo Hyun, Jeong, Jayoung, Kang, Byeong-Cheol, Che, Jeong-Hwan

“…Although silicon dioxide (SiO2), silver (Ag) and iron oxide (Fe2O3) nanoparticles are widely used in diverse applications from food to biomedicine, in vivo…”
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Adipose-derived mesenchymal stem cells reduce MMP-1 expression in UV-irradiated human dermal fibroblasts: therapeutic potential in skin wrinkling by Son, Woo-Chan, Yun, Jun-Won, Kim, Bae-Hwan

“…Adipose-derived mesenchymal stem cells (AdMSCs) have been reported to have therapeutic benefit in skin. The aim of this study was to examine the effects of…”
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Development of transgenic models susceptible and resistant to SARS-CoV-2 infection in FVB background mice by Seo, Sun-Min, Son, Jae Hyung, Lee, Ji-Hun, Kim, Na-Won, Yoo, Eun-Seon, Kang, Ah-Reum, Jang, Ji Yun, On, Da In, Noh, Hyun Ah, Yun, Jun-Won, Park, Jun Won, Choi, Kang-Seuk, Lee, Ho-Young, Shin, Jeon-Soo, Seo, Jun-Young, Nam, Ki Taek, Lee, Ho, Seong, Je Kyung, Choi, Yang-Kyu

“…Coronavirus disease (COVID-19), caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), is currently spreading globally. To overcome the…”
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Development of a neutralization monoclonal antibody with a broad neutralizing effect against SARS-CoV-2 variants by Ko, Hae Li, Lee, Deuk-Ki, Kim, Younghyeon, Jang, Hui Jeong, Lee, Youn Woo, Lee, Ho-Young, Seok, Sang-Hyuk, Park, Jun Won, Limb, Jin-Kyung, On, Da In, Yun, Jun-Won, Lyoo, Kwang-Soo, Song, Daesub, Yeom, Minjoo, Lee, Hanbyeul, Seong, Je Kyung, Lee, Sungjin

“…The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants has challenged the effectiveness of current therapeutic regimens. Here,…”
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Advances in selecting appropriate non-rodent species for regulatory toxicology research: Policy, ethical, and experimental considerations by Son, Yong-Wook, Choi, Ha-Ni, Che, Jeong-Hwan, Kang, Byeong-Cheol, Yun, Jun-Won

“…In vivo animal studies are required by regulatory agencies to investigate drug safety before clinical trials. In this review, we summarize the process of…”
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Toxicologic Evaluation for Amorphous Silica Nanoparticles: Genotoxic and Non-Genotoxic Tumor-Promoting Potential by Lee, Gwang-Hoon, Kim, Yun-Soon, Kwon, Euna, Yun, Jun-Won, Kang, Byeong-Cheol

“…Amorphous silica nanoparticles (SiO2NPs) have been widely used in medicine including targeted drug/DNA delivery, cancer therapy, and enzyme immobilization…”
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SARS-CoV-2 infection engenders heterogeneous ribonucleoprotein interactions to impede translation elongation in the lungs by Kim, Junsoo, Youn, Daehwa, Choi, Seunghoon, Lee, Youn Woo, Sumberzul, Dulguun, Yoon, Jeongeun, Lee, Hanju, Bae, Jong Woo, Noh, Hyuna, On, Dain, Hong, Seung-Min, An, Se-Hee, Jang, Hui Jeong, Kim, Seo Yeon, Kim, Young Been, Hwang, Ji-Yeon, Lee, Hyo-Jung, Bin Kim, Hong, Park, Jun Won, Yun, Jun-Won, Shin, Jeon-Soo, Seo, Jun-Young, Nam, Ki Taek, Choi, Kang-Seuk, Lee, Ho-Young, Chang, Hyeshik, Seong, Je Kyung, Cho, Jun

“…Translational regulation in tissue environments during in vivo viral pathogenesis has rarely been studied due to the lack of translatomes from virus-infected…”
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Design and Usability Evaluations of a 3D‐Printed Implantable Drug Delivery Device for Acute Liver Failure in Preclinical Settings by Kim, Shin‐Young, Han, Ginam, Hwang, Da‐Bin, Won, Dong‐Hoon, Shin, Yoo‐Sub, Kim, Changuk, Kang, Jeon Min, Park, Jung‐Hoon, Jung, Hyun‐Do, Park, Wooram, Yun, Jun‐Won

“…Acute liver failure (ALF) requiring liver transplantation is a disease that occurs due to rapid hepatocellular dysfunction. As liver transplantation has…”
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Induction of sestrin 2 is associated with fisetin-mediated apoptosis in human head and neck cancer cell lines by Won, Dong-Hoon, Chung, Shin Hye, Shin, Ji-Ae, Hong, Kyoung-Ok, Yang, In-Hyoung, Yun, Jun-Won, Cho, Sung-Dae

“…Fisetin was reported to have an anti-proliferative and apoptotic activity as a novel anti-cancer agent in various cancer cell lines. However, the possible…”
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TRPV1 antagonist can suppress the atopic dermatitis-like symptoms by accelerating skin barrier recovery by Yun, Jun-Won, Seo, Jung A, Jeong, Yeon Su, Bae, II-Hong, Jang, Won-Hee, Lee, Jihae, Kim, Sun-Young, Shin, Song-Seok, Woo, Byoung-Young, Lee, Ki-Wha, Lim, Kyung-Min, Park, Young-Ho

“…Abstract Background Transient receptor potential vanilloid type 1 (TRPV1) is a cation channel activated by diverse obnoxious stimuli like capsaicin, low pH or…”
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Antipruritic Effects of TRPV1 Antagonist in Murine Atopic Dermatitis and Itching Models by Yun, Jun-Won, Seo, Jung A., Jang, Won-Hee, Koh, Hyun Ju, Bae, Il-Hong, Park, Young-Ho, Lim, Kyung-Min

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Neurometabolic profiles of the substantia nigra and striatum of MPTP‐intoxicated common marmosets: An in vivo proton MRS study at 9.4 T by Heo, Hwon, Ahn, Jae‐Bum, Lee, Hyeong Hun, Kwon, Euna, Yun, Jun‐Won, Kim, Hyeonjin, Kang, Byeong‐Cheol

“…Given the strong coupling between the substantia nigra (SN) and striatum (STR) in the early stage of Parkinson's disease (PD), yet only a few studies reported…”
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Peptides Derived From S and N Proteins of Severe Acute Respiratory Syndrome Coronavirus 2 Induce T Cell Responses: A Proof of Concept for T Cell Vaccines by Lee, Yu-Sun, Hong, So-Hee, Park, Hyo-Jung, Lee, Ho-Young, Hwang, Ji-Yeon, Kim, Seo Yeon, Park, Jun Won, Choi, Kang-Seuk, Seong, Je Kyung, Park, Sang-In, Lee, Sang-Myeong, Hwang, Kyung-Ah, Yun, Jun-Won, Nam, Jae-Hwan

“…The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants that escape vaccine-induced neutralizing antibodies has indicated the…”
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YM155 induces apoptosis through downregulation of specificity protein 1 and myeloid cell leukemia-1 in human oral cancer cell lines by Sachita, Khadka, Yu, Hyun-Ju, Yun, Jun-Won, Lee, Jeong-Sang, Cho, Sung-Dae

“…Background YM155 is a small‐molecule pro‐apoptotic agent which has shown to inhibit survivin expression and induce apoptosis in various cancer cells. In this…”
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Role and mechanism of REG2 depletion in insulin secretion augmented by glutathione peroxidase-1 overproduction by Yan, Xi, Zhao, Zeping, Weaver, Jeremy, Sun, Tao, Yun, Jun-Won, Roneker, Carol A., Hu, Fenghua, Doliba, Nicolai M., McCormick, Charles Chipley W., Vatamaniuk, Marko Z., Lei, Xin Gen

“…We previously reported a depletion of murine regenerating islet-derived protein 2 (REG2) in pancreatic islets of glutathione peroxidase-1 (Gpx1) overexpressing…”
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Safety Assessment of Acer tegmentosum Maxim. Water Extract: General Toxicity Studies in Sprague–Dawley Rats and Beagle Dogs With Re-evaluation of Genotoxic Potentials by Park, Jin-Sung, Kwon, Euna, Kim, Yun-Soon, Kim, Sang-Moo, Kim, Dae-Sun, Jang, Ja-June, Yun, Jun-Won, Kang, Byeong-Cheol

“…Acer t egmentosum Maxim., commonly known as Manchurian stripe maple, is a deciduous tree belonging to the family of Aceraceae and has been traditionally used…”
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Egr1 Gene Expression as a Potential Biomarker for In Vitro Prediction of Ocular Toxicity by Hwang, Da-Bin, Kim, Shin-Young, Won, Dong-Hoon, Kim, Changuk, Shin, Yoo-Sub, Park, Jong-Hwan, Chun, Young-Jin, Lim, Kyung-Min, Yun, Jun-Won

“…Animal models are used for preclinical toxicity studies, and the need for in vitro alternative methods has been strongly raised. Our study aims to elucidate…”
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Gonadotropin ratio affects the in vitro growth of rhesus ovarian preantral follicles by Kim, Yoon Young, Yun, Jun-Won, Kim, Jong Min, Park, Chung Gyu, Rosenwaks, Zev, Liu, Hung Ching, Kang, Byeong-Cheol, Ku, Seung-Yup

“…In vitro follicle growth (IVFG) strategy is critical in the fertility preservation of cancer survivors; however, its optimal protocol needs to be developed…”
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