Search Results - "Julius, Heiko"

Novel aspects of cellular action of dipeptidyl peptidase IV/CD26 by Ansorge, Siegfried, Nordhoff, Karsten, Bank, Ute, Heimburg, Anke, Julius, Heiko, Breyer, Doreen, Thielitz, Anja, Reinhold, Dirk, Täger, Michael

“…The cellular dipeptidyl peptidase IV (DPIV, E.C.3.4.14.5, CD26) is a type II membrane peptidase with various physio-logical functions. Our main knowledge on…”
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A homogeneous cellular histone deacetylase assay suitable for compound profiling and robotic screening by Ciossek, Thomas, Julius, Heiko, Wieland, Heike, Maier, Thomas, Beckers, Thomas

“…Most cellular assays that quantify the efficacy of histone deacetylase (HDAC) inhibitors measure hyperacetylation of core histone proteins H3 and H4. Here we…”
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Trithiocarbonates as a Novel Class of HDAC Inhibitors: SAR Studies, Isoenzyme Selectivity, and Pharmacological Profiles by Dehmel, Florian, Weinbrenner, Steffen, Julius, Heiko, Ciossek, Thomas, Maier, Thomas, Stengel, Thomas, Fettis, Kamal, Burkhardt, Carmen, Wieland, Heike, Beckers, Thomas

“…Inhibitors of histone deacetylases (HDAC) are currently developed for the treatment of cancer. These include compounds with a sulfur containing head group like…”
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Outside or inside: role of the subcellular localization of DP4-like enzymes for substrate conversion and inhibitor effects by Bank, Ute, Heimburg, Anke, Wohlfarth, Astrid, Koch, Gudrun, Nordhoff, Karsten, Julius, Heiko, Helmuth, Martin, Breyer, Doreen, Reinhold, Dirk, Täger, Michael, Ansorge, Siegfried

“…The discovery of the DP4-related enzymes DP8 and DP9 raised controversial discussion regarding the physiological and pathophysiological function of distinct…”
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