Search Results - "Julius, Annabelle"
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Leukocyte function in the aging immune system
Published in Journal of leukocyte biology (01-06-2010)“…Review of the current understanding of age‐dependent changes in leukocyte function and their contribution to aging‐related disease processes. Aging is…”
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Impaired dendritic cell function in aging leads to defective antitumor immunity
Published in Cancer research (Chicago, Ill.) (01-08-2008)“…We recently reported that bone marrow-derived dendritic cells (DC) from aged miced are less effective than their young counterparts in inducing the regression…”
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The effect of aging and caloric restriction on murine CD8+ T cell chemokine receptor gene expression
Published in Immunity & ageing (14-11-2007)“…The mechanism explaining the increased disease susceptibility in aging is not well understood. CD8+ T cells are crucial in anti-viral and anti-tumor responses…”
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Aging is associated with an increase in T cells and inflammatory macrophages in visceral adipose tissue
Published in The Journal of immunology (1950) (15-12-2011)“…Age-related adiposity has been linked to chronic inflammatory diseases in late life. To date, the studies on adipose tissue leukocytes and aging have not taken…”
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5
Role of Epigenetics in Aging and Autoimmunity
Published in Clinical reviews in allergy & immunology (01-08-2010)“…The decline in immunocompetence with age is accompanied by the increase in the incidence of autoimmune diseases. Aging of the immune system, or…”
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Recombinant human erythropoietin stimulates melanoma tumor growth through activation of initiation factor eIF4E
Published in Oncotarget (02-05-2017)“…Recombinant human erythropoietin (EPO) is standard treatment for anemia in cancer patients. Recent clinical trials suggest that EPO may accelerate tumor…”
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Epigenetics, aging, and autoimmunity
Published in Autoimmunity (Chur, Switzerland) (01-01-2008)“…Immune senescence is associated with a decline in T- and B-cell immune responses. It is, therefore, perhaps surprising that aging is linked to the appearance…”
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Effect of Aging on Bone Marrow-Derived Murine CD11c+CD4−CD8α− Dendritic Cell Function
Published in The journals of gerontology. Series A, Biological sciences and medical sciences (01-10-2006)“…Dendritic cells (DCs) are actively used as cellular adjuvant in cancer immunotherapy. However, although DC immunotherapies primarily target the elderly…”
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Defective Dendritic Cell Phagocytic Function in Aging (134.36)
Published in The Journal of immunology (1950) (01-04-2009)“…Dendritic cells (DCs) play an important role in many immune-mediated processes in aging. One of their major functions is the phagocytic clearance of pathogens…”
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Mechanisms of murine dendritic cell antitumor dysfunction in aging
Published in Cancer Immunology, Immunotherapy (01-12-2009)“…Effective cancer immunotherapy depends on the body’s ability to generate tumor antigen-presenting cells and tumor-reactive effector lymphocytes. As the most…”
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Estrogen Regulates CCR Gene Expression and Function in T Lymphocytes
Published in The Journal of immunology (1950) (15-05-2005)“…Estrogen has been implicated in the observed female bias in autoimmune diseases. However, the mechanisms behind this gender dimorphism are poorly defined. We…”
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Impaired Dendritic Cell Migration and T cell Stimulation in Aging Lead to Defective Dendritic Cell‐Mediated Antitumor Immunity
Published in The FASEB journal (01-03-2008)“…Abstract only We recently reported that bone marrow‐derived dendritic cells (DCs) from old C57BL/6 mice are less effective than their young counterpart in…”
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Targeting MARCO can lead to enhanced dendritic cell motility and anti-melanoma activity
Published in Cancer Immunology, Immunotherapy (01-06-2010)“…We reported that murine tumor lysate-pulsed dendritic cells (TP-DC) could elicit tumor-specific CD4 + and CD8 + T cells in vitro and in vivo. In some limited…”
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Defective CCR7 function in aging: implications for dendritic cell migration (B156)
Published in The Journal of immunology (1950) (01-04-2007)“…We recently reported that bone marrow-derived dendritic cells (DCs) from old C57BL/6 mice are less effective than their young counterpart in inducing the…”
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15
Aging is associated with an increase in T cells and inflammatory macrophages in visceral adipose tissue1
Published in The Journal of immunology (1950) (09-11-2011)“…Age-related adiposity has been linked to chronic inflammatory diseases in late-life. To date, the studies on adipose tissue leukocytes and aging have not taken…”
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The Role of Epigenetics in Aging and Autoimmunity
Published in Autoimmunity (Chur, Switzerland) (01-05-2008)“…The decline in immunocompetence with age is accompanied by the increase in the incidence of autoimmune diseases. Aging of the immune system, or…”
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Journal Article -
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Effect of Aging on Bone Marrow-Derived Murine CD11c^sup +^CD4^sup -^CD8[alpha]^sup -^ Dendritic Cell Function
Published in The journals of gerontology. Series A, Biological sciences and medical sciences (01-10-2006)“…Dendritic cells (DCs) are actively used as cellular adjuvant in cancer immunotherapy. However, although DC immunotherapies primarily target the elderly…”
Get full text
Journal Article -
19
Effect of aging on bone marrow-derived murine CD11c+CD4-CD8alpha- dendritic cell function
Published in The journals of gerontology. Series A, Biological sciences and medical sciences (01-10-2006)“…Dendritic cells (DCs) are actively used as cellular adjuvant in cancer immunotherapy. However, although DC immunotherapies primarily target the elderly…”
Get full text
Journal Article