Search Results - "Julie Chang"

Beyond proteases: Basement membrane mechanics and cancer invasion by Chang, Julie, Chaudhuri, Ovijit

“…In epithelial cancers, cells must invade through basement membranes (BMs) to metastasize. The BM, a thin layer of extracellular matrix underlying epithelial…”
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Deep Optics for Monocular Depth Estimation and 3D Object Detection by Chang, Julie, Wetzstein, Gordon

“…Depth estimation and 3D object detection are critical for scene understanding but remain challenging to perform with a single image due to the loss of 3D…”
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Matrix mechanical plasticity regulates cancer cell migration through confining microenvironments by Wisdom, Katrina M., Adebowale, Kolade, Chang, Julie, Lee, Joanna Y., Nam, Sungmin, Desai, Rajiv, Rossen, Ninna Struck, Rafat, Marjan, West, Robert B., Hodgson, Louis, Chaudhuri, Ovijit

“…Studies of cancer cell migration have found two modes: one that is protease-independent, requiring micron-sized pores or channels for cells to squeeze through,…”
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Dose-Adjusted EPOCH-R Compared With R-CHOP as Frontline Therapy for Diffuse Large B-Cell Lymphoma: Clinical Outcomes of the Phase III Intergroup Trial Alliance/CALGB 50303 by Bartlett, Nancy L, Wilson, Wyndham H, Jung, Sin-Ho, Hsi, Eric D, Maurer, Matthew J, Pederson, Levi D, Polley, Mei-Yin C, Pitcher, Brandelyn N, Cheson, Bruce D, Kahl, Brad S, Friedberg, Jonathan W, Staudt, Louis M, Wagner-Johnston, Nina D, Blum, Kristie A, Abramson, Jeremy S, Reddy, Nishitha M, Winter, Jane N, Chang, Julie E, Gopal, Ajay K, Chadburn, Amy, Mathew, Susan, Fisher, Richard I, Richards, Kristy L, Schöder, Heiko, Zelenetz, Andrew D, Leonard, John P

“…Alliance/CALGB 50303 (NCT00118209), an intergroup, phase III study, compared dose-adjusted etoposide, prednisone, vincristine, cyclophosphamide, doxorubicin,…”
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YAP-independent mechanotransduction drives breast cancer progression by Lee, Joanna Y., Chang, Jessica K., Dominguez, Antonia A., Lee, Hong-pyo, Nam, Sungmin, Chang, Julie, Varma, Sushama, Qi, Lei S., West, Robert B., Chaudhuri, Ovijit

“…Increased tissue stiffness is a driver of breast cancer progression. The transcriptional regulator YAP is considered a universal mechanotransducer, based…”
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CALGB 50604: risk-adapted treatment of nonbulky early-stage Hodgkin lymphoma based on interim PET by Straus, David J., Jung, Sin-Ho, Pitcher, Brandelyn, Kostakoglu, Lale, Grecula, John C., Hsi, Eric D., Schöder, Heiko, Popplewell, Leslie L., Chang, Julie E., Moskowitz, Craig H., Wagner-Johnston, Nina, Leonard, John P., Friedberg, Jonathan W., Kahl, Brad S., Cheson, Bruce D., Bartlett, Nancy L.

“…A negative interim positron emission tomography/computerized tomography (PET/CT) after 1 to 3 cycles of doxorubicin, bleomycin, vinblastine, and dacarbazine…”
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Increased Programmed Death-Ligand 1 is an Early Epithelial Cell Response to Helicobacter pylori Infection by Holokai, Loryn, Chakrabarti, Jayati, Broda, Taylor, Chang, Julie, Hawkins, Jennifer A, Sundaram, Nambirajan, Wroblewski, Lydia E, Peek, Jr, Richard M, Wang, Jiang, Helmrath, Michael, Wells, James M, Zavros, Yana

“…Helicobacter pylori (H. pylori) is the major risk factor for the development of gastric cancer. Our laboratory has reported that the Sonic Hedgehog (Shh)…”
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Increased Stiffness Inhibits Invadopodia Formation and Cell Migration in 3D by Chang, Julie, Pang, Emily M., Adebowale, Kolade, Wisdom, Katrina M., Chaudhuri, Ovijit

“…Cancer cells typically invade through basement membranes (BMs) at key points during metastasis, including primary tumor invasion, intravasation, and…”
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Maintenance low-dose fixed duration lenalidomide and rituximab following bendamustine and rituximab induction in previously untreated chronic lymphocytic leukemia and small lymphocytic lymphoma by Chang, Julie E, Wang, Tuo, Kim, KyungMann, Folstad, Matthew, Endres, Mariah, Howard, Mitch, Kenkre, Vaishalee, Fletcher, Christopher, Rajguru, Saurabh

“…Lenalidomide (LEN) and rituximab (RTX) have independently improved progression-free survival (PFS) in CLL, leading to interest in use of LEN + RTX (R2)…”
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Matrix stiffness induces a tumorigenic phenotype in mammary epithelium through changes in chromatin accessibility by Stowers, Ryan S., Shcherbina, Anna, Israeli, Johnny, Gruber, Joshua J., Chang, Julie, Nam, Sungmin, Rabiee, Atefeh, Teruel, Mary N., Snyder, Michael P., Kundaje, Anshul, Chaudhuri, Ovijit

“…In breast cancer, the increased stiffness of the extracellular matrix is a key driver of malignancy. Yet little is known about the epigenomic changes that…”
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Phase I Study of the Anti-CD22 Antibody-Drug Conjugate Pinatuzumab Vedotin with/without Rituximab in Patients with Relapsed/Refractory B-cell Non-Hodgkin Lymphoma by Advani, Ranjana H, Lebovic, Daniel, Chen, Andy, Brunvand, Mark, Goy, Andre, Chang, Julie E, Hochberg, Ephraim, Yalamanchili, Sreeni, Kahn, Robert, Lu, Dan, Agarwal, Priya, Dere, Randall C, Hsieh, Hsin-Ju, Jones, Surai, Chu, Yu-Waye, Cheson, Bruce D

“…Pinatuzumab vedotin is an antibody-drug conjugate with the potent antimicrotubule agent monomethyl auristatin E (MMAE) conjugated to an anti-CD22 antibody via…”
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Maternal immunity shapes biomarkers of germinal center development in HIV-exposed uninfected infants by Yin, Li, Venturi, Guglielmo M, Barfield, Richard, Fischer, Bernard M, Kim-Chang, Julie J, Chan, Cliburn, De Paris, Kristina, Goodenow, Maureen M, Sleasman, John W

“…HIV-exposed uninfected (HEU) infants exhibit elevated pro-inflammatory biomarkers that persist after birth. However, comprehensive assessments of bioprofiles…”
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The genetics of Richter syndrome reveals disease heterogeneity and predicts survival after transformation by Rossi, Davide, Spina, Valeria, Deambrogi, Clara, Rasi, Silvia, Laurenti, Luca, Stamatopoulos, Kostas, Arcaini, Luca, Lucioni, Marco, Rocque, Gabrielle B., Xu-Monette, Zijun Y., Visco, Carlo, Chang, Julie, Chigrinova, Ekaterina, Forconi, Francesco, Marasca, Roberto, Besson, Caroline, Papadaki, Theodora, Paulli, Marco, Larocca, Luigi M., Pileri, Stefano A., Gattei, Valter, Bertoni, Francesco, Foà, Robin, Young, Ken H., Gaidano, Gianluca

“…Richter syndrome (RS) represents the development of diffuse large B-cell lymphoma in the context of chronic lymphocytic leukemia. The scarcity of biologic…”
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The nuclear piston activates mechanosensitive ion channels to generate cell migration paths in confining microenvironments by Lee, Hong-Pyo, Alisafaei, Farid, Adebawale, Kolade, Chang, Julie, Shenoy, Vivek B, Chaudhuri, Ovijit

“…Cell migration in confining microenvironments is limited by the ability of the stiff nucleus to deform through pores when migration paths are preexisting and…”
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Phase I Study of Dovitinib (TKI258), an Oral FGFR, VEGFR, and PDGFR Inhibitor, in Advanced or Metastatic Renal Cell Carcinoma by ANGEVIN, Eric, LOPEZ-MARTIN, Jose A, KAY, Andrea, ESCUDIER, Bernard, LIN, Chia-Chi, GSCHWEND, Jurgen E, HARZSTARK, Andrea, CASTELLANO, Daniel, SORIA, Jean-Charles, SEN, Paramita, JULIE CHANG, SHI, Michael

“…Signaling through the fibroblast growth factor (FGF) pathway may account for tumor resistance to antiangiogenic therapies targeting the VEGF pathway. Here,…”
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An Organoid-Based Preclinical Model of Human Gastric Cancer by Steele, Nina G, Chakrabarti, Jayati, Wang, Jiang, Biesiada, Jacek, Holokai, Loryn, Chang, Julie, Nowacki, Lauren M, Hawkins, Jennifer, Mahe, Maxime, Sundaram, Nambirajan, Shroyer, Noah, Medvedovic, Mario, Helmrath, Michael, Ahmad, Syed, Zavros, Yana

“…Background & Aims Our goal was to develop an initial study for the proof of concept whereby gastric cancer organoids are used as an approach to predict the…”
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Outcomes of limited stage primary bone diffuse large B-cell lymphoma in the rituximab era: a multicenter, retrospective study by Rezazadeh, Alexandra, Szabo, Aniko, Khurana, Arushi, Inwards, David J, Lunning, Matthew A, Bartlett, Nancy L, Caimi, Paolo F, Rodgers, Thomas D, Barr, Paul M, Chowdhury, Sayan Mullick, Epperla, Narendranath, Mendries, Hiruni, Hill, Brian T, Oh, Timothy S, Karmali, Reem, Chang, Julie E, Goyal, Gaurav, Parsons, Benjamin M, Isaac, Krista M, Portell, Craig A, Monahan, Kathleen, Siker, Malika, King, David M, Fenske, Timothy S

“…Primary bone diffuse large B-cell lymphoma is a rare variant of extranodal non-Hodgkin lymphoma historically treated with induction chemotherapy followed by…”
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Anti-inflammatory effects of recreational marijuana in virally suppressed youth with HIV-1 are reversed by use of tobacco products in combination with marijuana by Yin, Li, Dinasarapu, Ashok R, Borkar, Samiksha A, Chang, Kai-Fen, De Paris, Kristina, Kim-Chang, Julie J, Sleasman, John W, Goodenow, Maureen M

“…Marijuana's putative anti-inflammatory properties may benefit HIV-associated comorbidities. How recreational marijuana use affects gene expression in…”
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Mask‐Wearing Behavior During the COVID‐19 Pandemic: A Cross‐Cultural Comparison Between the United States and South Korea by Chang, Hyo Jung (Julie), Min, Seoha, Woo, Hongjoo, Yurchisin, Jennifer

“…This study identified and compared factors that directly and indirectly influenced face mask‐wearing in the United States and South Korea during the COVID‐19…”
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Phase 1 dose escalation multicenter trial of pracinostat alone and in combination with azacitidine in patients with advanced hematologic malignancies by Abaza, Yasmin M., Kadia, Tapan M., Jabbour, Elias J., Konopleva, Marina Y., Borthakur, Gautam, Ferrajoli, Alessandra, Estrov, Zeev, Wierda, William G., Alfonso, Ana, Chong, Toh Han, Chuah, Charles, Koh, Liang‐Piu, Goh, Boon‐Cher, Chang, Julie E., Durkes, Daniel E., Foudray, Maria Cielo, Kantarjian, Hagop M., Dong, Xiao Qin, Garcia‐Manero, Guillermo

“…BACKGROUND Pracinostat is a potent histone deacetylase inhibitor with antitumor activity in both solid tumor and acute myeloid leukemia (AML) cell lines…”
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