Search Results - "Juliana Lott Carvalho"
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Correlation of Parasite Burden, kDNA Integration, Autoreactive Antibodies, and Cytokine Pattern in the Pathophysiology of Chagas Disease
Published in Frontiers in microbiology (21-08-2019)“…Chagas disease (CD), caused by the protozoan ( ), is the main parasitic disease in the Western Hemisphere. Unfortunately, its physiopathology is not completely…”
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2
Assessment of the Immunosuppressive Potential of INF-γ Licensed Adipose Mesenchymal Stem Cells, Their Secretome and Extracellular Vesicles
Published in Cells (Basel, Switzerland) (05-01-2019)“…There is an active search for the ideal strategy to potentialize the effects of Mesenchymal Stem-Cells (MSCs) over the immune system. Also, part of the…”
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3
IFN- γ -Licensed Mesenchymal Stem Cells Are More Susceptible to Death when Exposed to Quorum-Sensing Signal Molecule OdDHL and Less Effective in Inhibiting the Growth of Pseudomonas aeruginosa
Published in Stem cells international (30-07-2024)“…Currently, a series of licensing strategies has been investigated to enhance the functional properties of mesenchymal stem cells (MSCs). Licensing with IFN- is…”
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4
Nanostructured lipid carriers loaded with an association of minoxidil and latanoprost for targeted topical therapy of alopecia
Published in European journal of pharmaceutics and biopharmaceutics (01-03-2022)“…[Display omitted] •Minoxidil and latanoprost are compatible, which enabled their association.•The drugs combination’s bioactivity was encouraging, especially…”
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5
Production of Human Endothelial Cells Free from Soluble Xenogeneic Antigens for Bioartificial Small Diameter Vascular Graft Endothelization
Published in BioMed research international (01-01-2015)“…Arterial bypass graft implantation remains the primary therapy for patients with advanced cardiovascular disease, but most lack adequate saphenous vein or…”
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Adenosine production: a common path for mesenchymal stem-cell and regulatory T-cell-mediated immunosuppression
Published in Purinergic signalling (01-12-2016)“…Adenosine is an important molecule that exerts control on the immune system, by signaling through receptors lying on the surface of immune cells. This…”
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Mesenchymal Stem Cells: A New Piece in the Puzzle of COVID-19 Treatment
Published in Frontiers in immunology (03-07-2020)“…COVID-19 is a disease characterized by a strong inflammatory response in severe cases, which fails to respond to corticosteroid therapy. In the context of the…”
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Characterization of ibrutinib's effects on the morphology, proliferation, phenotype, viability, and anti-inflammatory potential of adipose-derived mesenchymal stromal cells
Published in Scientific reports (28-08-2024)“…Ibrutinib (IB) is a tyrosine kinase inhibitor (TKI) that has immunomodulatory action and can be used as second-line therapy for steroid-refractory or…”
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9
Screening of the Skin-Regenerative Potential of Antimicrobial Peptides: Clavanin A, Clavanin-MO, and Mastoparan-MO
Published in International journal of molecular sciences (01-07-2024)“…Skin wound healing is coordinated by a delicate balance between proinflammatory and anti-inflammatory responses, which can be affected by opportunistic…”
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Pouteria macrophylla Fruit Extract Microemulsion for Cutaneous Depigmentation: Evaluation Using a 3D Pigmented Skin Model
Published in Molecules (Basel, Switzerland) (14-09-2022)“…Here, we verify the depigmenting action of Pouteria macrophylla fruit extract (EXT), incorporate it into a safe topical microemulsion and assess its…”
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11
Commentary: Mesenchymal Stem Cells: A New Piece in the Puzzle of COVID-19 Treatment
Published in Frontiers in immunology (29-04-2021)Get full text
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12
Immunomodulatory effect of IFN-γ licensed adipose-mesenchymal stromal cells in an in vitro model of inflammation generated by SARS-CoV-2 antigens
Published in Scientific reports (16-10-2024)“…In recent years, clinical studies have shown positive results of the application of Mesenchymal Stromal Cells (MSCs) in severe cases of COVID-19. However, the…”
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13
Multiparametric analysis of host and parasite elements in new world tegumentary leishmaniasis
Published in Frontiers in cellular and infection microbiology (09-08-2022)“…Tegumentary leishmaniasis is a tropical disease caused by protozoa of the genus Leishmania. Clinically, the disease presents a broad spectrum of symptoms, the…”
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14
The Combination of Synoeca-MP Antimicrobial Peptide with IDR-1018 Stimulates Proliferation, Migration, and the Expression of Pro-Regenerative Genes in Both Human Skin Cell Cultures and 3D Skin Equivalents
Published in Biomolecules (Basel, Switzerland) (09-05-2023)“…In skin lesions, the development of microbial infection affects the healing process, increasing morbidity and mortality rates in patients with severe burns,…”
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15
IDR‐1018 induces cell proliferation, migration, and reparative gene expression in 2D culture and 3D human skin equivalents
Published in Journal of tissue engineering and regenerative medicine (01-11-2019)“…Skin lesions are associated with functional/cosmetic problems for those afflicted. Scarless regeneration is a challenge, not limited to the skin, and focus of…”
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Ibrutinib Modulates Proliferation, Migration, Mitochondrial Homeostasis, and Apoptosis in Melanoma Cells
Published in Biomedicines (01-05-2024)“…Ibrutinib, a tyrosine kinase inhibitor with a broad spectrum of action, has been successfully explored to treat hematological and solid cancers. Herein, we…”
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Development and Validation of a Chromatographic Method for Ibrutinib Determination in Human and Porcine Skin
Published in Chemistry an international journal (01-04-2024)“…Ibrutinib (IBR) is a tyrosine kinase inhibitor investigated for treating solid and non-solid tumors. Considering the advantages that a topical application of…”
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Molecular and functional anticancer effects of GLP/G9a inhibition by UNC0646 in MeWo melanoma cells
Published in Heliyon (15-03-2024)“…In recent years, histone methyltransferases (HMTs) have emerged as important therapeutic targets in cancer due to their oncogenic role. Herein, we used the…”
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Skin Regenerative Potential of Cupuaçu Seed Extract ( Theobroma grandiflorum ), a Native Fruit from the Amazon: Development of a Topical Formulation Based on Chitosan-Coated Nanocapsules
Published in Pharmaceutics (16-01-2022)“…Scarless skin regeneration is a challenge in regenerative medicine. Herein, we explore the regenerative potential of a Cupuaçu seed extract ( ) to develop an…”
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Doxorubicin has in vivo toxicological effects on ex vivo cultured mesenchymal stem cells
Published in Toxicology letters (30-01-2014)“…•Mesenchymal stem cells (MSCs) were isolated from rats that received doxorubicin.•Doxorubicin had toxic effects on MSCs.•MSCs grew up in lower rates and had…”
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