Search Results - "Julian, T"

Risk‐of‐bias VISualization (robvis): An R package and Shiny web app for visualizing risk‐of‐bias assessments by McGuinness, Luke A., Higgins, Julian P. T.

“…Despite a major increase in the range and number of software offerings now available to help researchers produce evidence syntheses, there is currently no…”
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Graphical tools for network meta-analysis in STATA by Chaimani, Anna, Higgins, Julian P T, Mavridis, Dimitris, Spyridonos, Panagiota, Salanti, Georgia

“…Network meta-analysis synthesizes direct and indirect evidence in a network of trials that compare multiple interventions and has the potential to rank the…”
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CINeMA: An approach for assessing confidence in the results of a network meta-analysis by Nikolakopoulou, Adriani, Higgins, Julian P T, Papakonstantinou, Theodoros, Chaimani, Anna, Del Giovane, Cinzia, Egger, Matthias, Salanti, Georgia

“…The evaluation of the credibility of results from a meta-analysis has become an important part of the evidence synthesis process. We present a methodological…”
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Evaluating the quality of evidence from a network meta-analysis by Salanti, Georgia, Del Giovane, Cinzia, Chaimani, Anna, Caldwell, Deborah M, Higgins, Julian P T

“…Systematic reviews that collate data about the relative effects of multiple interventions via network meta-analysis are highly informative for decision-making…”
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Future therapies for cystic fibrosis by Allen, Lucy, Allen, Lorna, Carr, Siobhan B., Davies, Gwyneth, Downey, Damian, Egan, Marie, Forton, Julian T., Gray, Robert, Haworth, Charles, Horsley, Alexander, Smyth, Alan R., Southern, Kevin W., Davies, Jane C.

“…We are currently witnessing transformative change for people with cystic fibrosis with the introduction of small molecule, mutation-specific drugs capable of…”
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A comparison of heterogeneity variance estimators in simulated random‐effects meta‐analyses by Langan, Dean, Higgins, Julian P.T., Jackson, Dan, Bowden, Jack, Veroniki, Areti Angeliki, Kontopantelis, Evangelos, Viechtbauer, Wolfgang, Simmonds, Mark

“…Studies combined in a meta‐analysis often have differences in their design and conduct that can lead to heterogeneous results. A random‐effects model accounts…”
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The Prevalence of Non-Alcoholic Fatty Liver Disease in Children and Adolescents: A Systematic Review and Meta-Analysis by Anderson, Emma L, Howe, Laura D, Jones, Hayley E, Higgins, Julian P T, Lawlor, Debbie A, Fraser, Abigail

“…Narrative reviews of paediatric NAFLD quote prevalences in the general population that range from 9% to 37%; however, no systematic review of the prevalence of…”
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Empirical Evidence of Study Design Biases in Randomized Trials: Systematic Review of Meta-Epidemiological Studies by Page, Matthew J, Higgins, Julian P T, Clayton, Gemma, Sterne, Jonathan A C, Hróbjartsson, Asbjørn, Savović, Jelena

“…To synthesise evidence on the average bias and heterogeneity associated with reported methodological features of randomized trials. Systematic review of…”
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Methods to estimate the between-study variance and its uncertainty in meta-analysis by Veroniki, Areti Angeliki, Jackson, Dan, Viechtbauer, Wolfgang, Bender, Ralf, Bowden, Jack, Knapp, Guido, Kuss, Oliver, Higgins, Julian PT, Langan, Dean, Salanti, Georgia

“…Meta‐analyses are typically used to estimate the overall/mean of an outcome of interest. However, inference about between‐study variability, which is typically…”
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FlyAtlas 2: a new version of the Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data by Leader, David P, Krause, Sue A, Pandit, Aniruddha, Davies, Shireen A, Dow, Julian A T

“…Abstract FlyAtlas 2 (www.flyatlas2.org) is part successor, part complement to the FlyAtlas database and web application for studying the expression of the…”
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Pro-inflammatory T helper 17 directly harms oligodendrocytes in neuroinflammation by Larochelle, Catherine, Wasser, Beatrice, Jamann, Hélène, Löffel, Julian T., Cui, Qiao-Ling, Tastet, Olivier, Schillner, Miriam, Luchtman, Dirk, Birkenstock, Jérôme, Stroh, Albrecht, Antel, Jack, Bittner, Stefan, Zipp, Frauke

“…T helper (Th)17 cells are considered to contribute to inflammatory mechanisms in diseases such as multiple sclerosis (MS). However, the discussion persists…”
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Strengthening the Reporting of Observational Studies in Epidemiology Using Mendelian Randomization: The STROBE-MR Statement by Skrivankova, Veronika W, Richmond, Rebecca C, Woolf, Benjamin A. R, Yarmolinsky, James, Davies, Neil M, Swanson, Sonja A, VanderWeele, Tyler J, Higgins, Julian P. T, Timpson, Nicholas J, Dimou, Niki, Langenberg, Claudia, Golub, Robert M, Loder, Elizabeth W, Gallo, Valentina, Tybjaerg-Hansen, Anne, Davey Smith, George, Egger, Matthias, Richards, J. Brent

“…IMPORTANCE: Mendelian randomization (MR) studies use genetic variation associated with modifiable exposures to assess their possible causal relationship with…”
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Pathogen detection. The bread and butter by Forton, Julian T.

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Meta-Analysis and Subgroups by Borenstein, Michael, Higgins, Julian P. T.

“…Subgroup analysis is the process of comparing a treatment effect for two or more variants of an intervention—to ask, for example, if an intervention’s impact…”
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Conceptual and Technical Challenges in Network Meta-analysis by CIPRIANI, Andrea, HIGGINS, Julian P. T, GEDDES, John R, SALANTI, Georgia

“…The increase in treatment options creates an urgent need for comparative effectiveness research. Randomized, controlled trials comparing several treatments are…”
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Rapid Structure Determination of Microcrystalline Molecular Compounds Using Electron Diffraction by Gruene, Tim, Wennmacher, Julian T. C., Zaubitzer, Christan, Holstein, Julian J., Heidler, Jonas, Fecteau‐Lefebvre, Ariane, De Carlo, Sacha, Müller, Elisabeth, Goldie, Kenneth N., Regeni, Irene, Li, Teng, Santiso‐Quinones, Gustavo, Steinfeld, Gunther, Handschin, Stephan, van Genderen, Eric, van Bokhoven, Jeroen A., Clever, Guido H., Pantelic, Radosav

“…Chemists of all fields currently publish about 50 000 crystal structures per year, the vast majority of which are X‐ray structures. We determined two molecular…”
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Detecting respiratory infection in children with cystic fibrosis: Cough swab, sputum induction or bronchoalveolar lavage by Forton, Julian T.

“…Young children with cystic fibrosis (CF) are generally very well, cough free and non-productive, and are often incapable of spontaneously expectorating sputum…”
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A re-evaluation of fixed effect(s) meta-analysis by Rice, Kenneth, Higgins, Julian P. T., Lumley, Thomas

“…Meta-analysis is a common tool for synthesizing results of multiple studies. Among methods for performing meta-analysis, the approach known as 'fixed effects'…”
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Association Between Administration of Systemic Corticosteroids and Mortality Among Critically Ill Patients With COVID-19: A Meta-analysis by Sterne, Jonathan A. C, Murthy, Srinivas, Diaz, Janet V, Slutsky, Arthur S, Villar, Jesús, Angus, Derek C, Annane, Djillali, Azevedo, Luciano Cesar Pontes, Berwanger, Otavio, Cavalcanti, Alexandre B, Dequin, Pierre-Francois, Du, Bin, Emberson, Jonathan, Fisher, David, Giraudeau, Bruno, Gordon, Anthony C, Granholm, Anders, Green, Cameron, Haynes, Richard, Heming, Nicholas, Higgins, Julian P. T, Horby, Peter, Jüni, Peter, Landray, Martin J, Le Gouge, Amelie, Leclerc, Marie, Lim, Wei Shen, Machado, Flávia R, McArthur, Colin, Meziani, Ferhat, Møller, Morten Hylander, Perner, Anders, Petersen, Marie Warrer, Savovic, Jelena, Tomazini, Bruno, Veiga, Viviane C, Webb, Steve, Marshall, John C

“…IMPORTANCE: Effective therapies for patients with coronavirus disease 2019 (COVID-19) are needed, and clinical trial data have demonstrated that low-dose…”
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Functional characteristics of Th1, Th17, and ex-Th17 cells in EAE revealed by intravital two-photon microscopy by Loos, Julia, Schmaul, Samantha, Noll, Theresa Marie, Paterka, Magdalena, Schillner, Miriam, Löffel, Julian T, Zipp, Frauke, Bittner, Stefan

“…Abstract Background T helper (Th) 17 cells are a highly plastic subset of T cells, which in the context of neuroinflammation, are able to acquire pathogenic…”
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