Search Results - "Julian, C"
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1
The emerging role of urease as a general microbial virulence factor
Published in PLoS pathogens (01-05-2014)“… [...]urease-mediated pH changes and damage to host epithelial cells are associated with the promotion of some bacterial infections. [...]mice infected with…”
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2
State of the science in health professional education: effective feedback
Published in Medical education (01-01-2010)“…Background Effective feedback may be defined as feedback in which information about previous performance is used to promote positive and desirable…”
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3
Major Histocompatibility Complex Genomics and Human Disease
Published in Annual review of genomics and human genetics (01-01-2013)“…Over several decades, various forms of genomic analysis of the human major histocompatibility complex (MHC) have been extremely successful in picking up many…”
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The role of Indigenous peoples and local communities in effective and equitable conservation
Published in Ecology and society (2021)“…Debate about what proportion of the Earth to protect often overshadows the question of how nature should be conserved and by whom. We present a systematic…”
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Gut microbiota in regulation of childhood bone growth
Published in Experimental physiology (01-05-2024)“…Childhood stunting and wasting, or decreased linear and ponderal growth associated with undernutrition, continue to be a major global public health challenge…”
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6
Radicals: Reactive Intermediates with Translational Potential
Published in Journal of the American Chemical Society (05-10-2016)“…This Perspective illustrates the defining characteristics of free radical chemistry, beginning with its rich and storied history. Studies from our laboratory…”
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7
Reducing Crime and Violence: Experimental Evidence from Cognitive Behavioral Therapy in Liberia
Published in The American economic review (01-04-2017)“…We show that a number of noncognitive skills and preferences, including patience and identity, are malleable in adults, and that investments in them reduce…”
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Engineered triply orthogonal pyrrolysyl–tRNA synthetase/tRNA pairs enable the genetic encoding of three distinct non-canonical amino acids
Published in Nature chemistry (01-06-2020)“…Expanding and reprogramming the genetic code of cells for the incorporation of multiple distinct non-canonical amino acids (ncAAs), and the encoded…”
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Host genetics and infectious disease: new tools, insights and translational opportunities
Published in Nature reviews. Genetics (01-03-2021)“…Understanding how human genetics influence infectious disease susceptibility offers the opportunity for new insights into pathogenesis, potential drug targets,…”
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10
A Practical and Catalytic Reductive Olefin Coupling
Published in Journal of the American Chemical Society (29-01-2014)“…A redox-economic method for the direct coupling of olefins that uses an inexpensive iron catalyst and a silane reducing agent is reported. Thus, unactivated…”
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11
Mutually orthogonal pyrrolysyl-tRNA synthetase/tRNA pairs
Published in Nature chemistry (01-08-2018)“…Genetically encoding distinct non-canonical amino acids (ncAAs) into proteins synthesized in cells requires mutually orthogonal aminoacyl-tRNA synthetase…”
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12
Home for a rest: stem cell niche of the postnatal growth plate
Published in Journal of endocrinology (01-07-2020)“…The resting zone houses a group of slowly proliferating ‘reserve’ chondrocytes and has long been speculated to serve as the stem cell niche of the postnatal…”
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13
Functionalized olefin cross-coupling to construct carbon–carbon bonds
Published in Nature (London) (18-12-2014)“…Carbon–carbon (C–C) bonds form the backbone of many important molecules, including polymers, dyes and pharmaceutical agents. The development of new methods to…”
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14
Epigenetic Causes of Overgrowth Syndromes
Published in The journal of clinical endocrinology and metabolism (18-01-2024)“…Abstract Human overgrowth disorders are characterized by excessive prenatal and/or postnatal growth of various tissues. These disorders often present with tall…”
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The association between endometriosis and autoimmune diseases: a systematic review and meta-analysis
Published in Human reproduction update (01-07-2019)“…Abstract BACKGROUND Endometriosis is a chronic gynaecological disorder that affects 2–10% of women of reproductive age. The aetiology of endometriosis is…”
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16
Artificial Intelligence in Radiotherapy Treatment Planning: Present and Future
Published in Technology in Cancer Research & Treatment (2019)“…Treatment planning is an essential step of the radiotherapy workflow. It has become more sophisticated over the past couple of decades with the help of…”
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Elevated Translocator Protein in Anterior Cingulate in Major Depression and a Role for Inflammation in Suicidal Thinking: A Positron Emission Tomography Study
Published in Biological psychiatry (1969) (01-01-2018)“…Major depressive disorder is associated with raised peripheral inflammatory markers. Mounting evidence also suggests that inflammation is involved in suicidal…”
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Effect of flavonols on wine astringency and their interaction with human saliva
Published in Food chemistry (15-10-2016)“…•Flavonol addition to wines yields in an increase in the astringency and bitterness.•Flavonols interact with salivary proteins forming…”
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Probing New Long-Range Interactions by Isotope Shift Spectroscopy
Published in Physical review letters (26-02-2018)“…We explore a method to probe new long- and intermediate-range interactions using precision atomic isotope shift spectroscopy. We develop a formalism to…”
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Priority index: database of genetic targets in immune-mediated disease
Published in Nucleic acids research (07-01-2022)“…Abstract We describe a comprehensive and unique database ‘Priority index’ (Pi; http://pi.well.ox.ac.uk) of prioritized genes encoding potential therapeutic…”
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