Search Results - "Juknevičienė, Milda"
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The effect of valproic acid on SLC5A8 expression in gonad-intact and gonadectomized rat thymocytes
Published in International journal of immunopathology and pharmacology (01-01-2022)“…Background Valproic acid (VPA) pharmacological mechanisms are related to the anti-inflammatory and anti-viral effects. VPA is a histone deacetylases inhibitor…”
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The Effectiveness of Dichloroacetate on Human Glioblastoma Xenograft Growth Depends on Na+ and Mg2+ Cations
Published in Dose-response (01-01-2021)“…The study’s aim was to investigate the effectiveness of sodium dichloroacetate (NaDCA) or magnesium dichloroacetate (MgDCA) on adult U87 MG and pediatric PBT24…”
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Differential Impact of Valproic Acid on SLC5A8 , SLC12A2 , SLC12A5 , CDH1 , and CDH2 Expression in Adult Glioblastoma Cells
Published in Biomedicines (25-06-2024)“…Valproic acid (VPA) has anticancer, anti-inflammatory, and epigenetic effects. The study aimed to determine the expression of carcinogenesis-related , , , and…”
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Sodium Dichloroacetate Pharmacological Effect as Related to Na–K–2Cl Cotransporter Inhibition in Rats
Published in Dose-response (01-10-2018)“…The study objective was to investigate a possible sodium dichloroacetate (DCA) pharmacological mechanism causing an increase in diuresis in rats. The aim was…”
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Gender-Related Effect of Sodium Dichloroacetate on the Number of Hassall’s Corpuscles and RNA NKCC1 Expression in Rat Thymus
Published in BioMed research international (01-01-2019)“…The aim was to investigate the effect of dichloroacetate (DCA) on thymus weight, Hassall’s corpuscle number (HCs), and NKCC1 RNA expression in Wistar rats aged…”
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Valproic Acid Inhibits NA-K-2CL Cotransporter RNA Expression in Male But Not in Female Rat Thymocytes
Published in Dose-response (01-04-2019)“…Objective: The NKCC1 is a recognized tumorigenesis marker as it is important for tumor cell proliferation, differentiation, apoptosis, and tumor progression…”
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ABO blood group polymorphism has an impact on prostate, kidney and bladder cancer in association with longevity
Published in Oncology letters (01-07-2018)“…The aim of the present study was to assess the ABO blood group polymorphism association with prostate, bladder and kidney cancer, and longevity. The following…”
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The Importance of Gender-Related Anticancer Research on Mitochondrial Regulator Sodium Dichloroacetate in Preclinical Studies In Vivo
Published in Cancers (20-08-2019)“…Sodium dichloroacetate (DCA) is an investigational medicinal product which has a potential anticancer preparation as a metabolic regulator in cancer cells'…”
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