Search Results - "Juji, Takeo"
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High-risk HLA allele mismatch combinations responsible for severe acute graft-versus-host disease and implication for its molecular mechanism
Published in Blood (01-10-2007)“…In allogenic hematopoietic stem-cell transplantation, an effect of HLA locus mismatch in allele level on clinical outcome has been clarified. However, the…”
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Therapeutic activation of Vα24+Vβ11+ NKT cells in human subjects results in highly coordinated secondary activation of acquired and innate immunity
Published in Blood (15-01-2004)“…Human Vα24+Vβ11+ natural killer T (NKT) cells are a distinct CD1d-restricted lymphoid subset specifically and potently activated by α-galactosylceramide…”
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3
Genetic origins of the Ainu inferred from combined DNA analyses of maternal and paternal lineages
Published in Journal of human genetics (01-04-2004)“…The Ainu, a minority ethnic group from the northernmost island of Japan, was investigated for DNA polymorphisms both from maternal (mitochondrial DNA) and…”
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4
Effect of Matching of Class I HLA Alleles on Clinical Outcome after Transplantation of Hematopoietic Stem Cells from an Unrelated Donor
Published in The New England journal of medicine (22-10-1998)“…Patients with malignant hematologic diseases, various forms of marrow failure, and certain congenital disorders can be successfully treated with…”
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Genomewide Association Analysis of Human Narcolepsy and a New Resistance Gene
Published in American journal of human genetics (01-08-2006)“…Human narcolepsy is a hypersomnia that is affected by multiple genetic and environmental factors. One genetic factor strongly associated with narcolepsy is the…”
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6
Polymorphism in RANTES Chemokine Promoter Affects HIV-1 Disease Progression
Published in Proceedings of the National Academy of Sciences - PNAS (13-04-1999)“…RANTES (regulated on activation normal T cell expressed and secreted) is one of the natural ligands for the chemokine recptor CCR5 and potently suppresses in…”
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TGF-β1 Reciprocally Controls Chemotaxis of Human Peripheral Blood Monocyte-Derived Dendritic Cells Via Chemokine Receptors
Published in The Journal of immunology (1950) (01-03-2000)“…Abstract We examined the effect of TGF-β1 on the chemotactic migratory ability of human monocyte-derived dendritic cells (DCs). Treatment of immature DCs with…”
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Highly efficient recovery of functional single-chain Fv fragments from inclusion bodies overexpressed in Escherichia coli by controlled introduction of oxidizing reagent—application to a human single-chain Fv fragment
Published in Journal of immunological methods (01-10-1998)“…An improved and efficient refolding system for a single-chain antibody fragment (scFv) from inclusion bodies expressed in Escherichia coli was developed…”
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9
Genetic link between Asians and native Americans: evidence from HLA genes and haplotypes
Published in Human immunology (01-09-2001)“…We have been studying polymorphisms of HLA class I and II genes in East Asians including Buryat in Siberia, Mongolian, Han Chinese, Man Chinese, Korean…”
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10
Activation and suppression of renin–angiotensin system in human dendritic cells
Published in Biochemical and biophysical research communications (09-08-2002)“…We previously identified the gene expression of renin–angiotensin system in human monocyte-derived dendritic cells (DCs). This study was conducted to examine…”
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11
IL-12 Responsiveness and Expression of IL-12 Receptor in Human Peripheral Blood Monocyte-Derived Dendritic Cells
Published in The Journal of immunology (1950) (01-07-2000)“…We analyzed the expression of IL-12Rbeta1 and IL-12Rbeta2 and the role of IL-12 in the activation of monocyte-derived dendritic cells (DCs) via…”
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12
Killer Cell Immunoglobulin Receptors and T Cell Receptors Bind Peptide-Major Histocompatibility Complex Class I with Distinct Thermodynamic and Kinetic Properties
Published in The Journal of biological chemistry (01-10-1999)“…Human natural killer cells and a subset of T cells express a repertoire of killer cell immunoglobulin receptors (KIRs) that recognize major histocompatibility…”
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13
Frequent presence of HBV in the sera of HBsAg-negative, anti-HBc-positive blood donors
Published in Transfusion (Philadelphia, Pa.) (01-09-2001)“…BACKGROUND: Recent studies have revealed that HBV may not be cleared even after the disappearance of serum HBsAg. The purpose of this study was to investigate…”
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14
Crystal structure of the human p58 killer cell inhibitory receptor (KIR2DL3) specific for HLA-Cw3-related MHC class I
Published in Structure (London) (15-04-1999)“…Background: T cells and natural killer (NK) cells perform complementary roles in the cellular immune system. T cells identify infected cells directly through…”
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15
Three major lineages of Asian Y chromosomes: implications for the peopling of east and southeast Asia
Published in Human genetics (01-01-2002)“…DNA variation on the non-recombining portion of the Y chromosome was examined in 610 male samples from 14 global populations in north, east, and southeast…”
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16
Sequence-based association analysis of HLA class I and II alleles in Japanese supports conservation of common haplotypes
Published in Immunogenetics (New York) (01-01-1997)“…Alleles of HLA-A, B, C, DRB1, DQB1, and DPB1 loci were fully determined in 117 healthy Japanese. A*2402, A*3303, A*1101, A*0201, B*4403, B*5201, Cw*0102,…”
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CC chemokine receptors, CCR-1 and CCR-3, are potentially involved in antigen-presenting cell function of human peripheral blood monocyte-derived dendritic cells
Published in Blood (1999)“…We examined the potential involvement of two CC chemokine receptors (CCRs), CCR-1 and CCR-3, in the functional activation of granulocyte-macrophage…”
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18
Extensive polymorphism of ABO blood group gene : three major lineages of the alleles for the common ABO phenotypes
Published in Human genetics (01-06-1996)“…Polymorphism of the ABO blood group gene was investigated in 262 healthy Japanese donors by a polymerase chain reactions-single-strand conformation…”
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MIC-A polymorphism in Japanese and a MIC-A-MIC-B null haplotype
Published in Immunogenetics (New York) (01-07-1999)“…A polymorphic gene, MIC-A, is one of the MIC family of genes which is composed of a group of homologous genes interspersed in the class III and class I regions…”
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Signaling events following chemokine receptor ligation in human dendritic cells at different developmental stages
Published in International immunology (01-02-2001)“…Responsiveness of dendritic cells (DC) to inflammatory CC chemokines is down-regulated during their maturation. We analyzed the mechanism underlying these…”
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