Search Results - "Jugniot, Natacha"
-
1
Expression and purification of a native Thy1-single-chain variable fragment for use in molecular imaging
Published in Scientific reports (29-11-2021)“…Molecular imaging using singlechain variable fragments (scFv) of antibodies targeting cancer specific antigens have been considered a non-immunogenic approach…”
Get full text
Journal Article -
2
Immunotheranostic microbubbles (iMBs) - a modular platform for dendritic cell vaccine delivery applied to breast cancer immunotherapy
Published in Journal of experimental & clinical cancer research (12-10-2022)“…Therapeutic strategies engaging the immune system against malignant cells have revolutionized the field of oncology. Proficiency of dendritic cells (DCs) for…”
Get full text
Journal Article -
3
Biomimetic nanobubbles for triple-negative breast cancer targeted ultrasound molecular imaging
Published in Journal of nanobiotechnology (10-06-2022)“…Triple-negative breast cancer (TNBC) is a highly heterogeneous breast cancer subtype with poor prognosis. Although anatomical imaging figures prominently for…”
Get full text
Journal Article -
4
-
5
Current status of targeted microbubbles in diagnostic molecular imaging of pancreatic cancer
Published in Bioengineering & translational medicine (01-01-2021)“…Pancreatic ductal adenocarcinoma (PDAC) is often associated with a poor prognosis due to silent onset, resistance to therapies, and rapid spreading. Most…”
Get full text
Journal Article -
6
Magnetic Resonance Imaging of Protease-Mediated Lung Tissue Inflammation and Injury
Published in ACS omega (15-06-2021)“…Pulmonary inflammation usually involves strong neutrophil recruitment with a marked release of proteases such as neutrophil elastase (NE). Noninvasive in vivo…”
Get full text
Journal Article -
7
-
8
Neutrophil Elastase Activity Imaging: Recent Approaches in the Design and Applications of Activity-Based Probes and Substrate-Based Probes
Published in Contrast media and molecular imaging (01-01-2019)“…The last few decades of protease research has confirmed that a number of important biological processes are strictly dependent on proteolysis. Neutrophil…”
Get full text
Journal Article -
9
Shifting-Nitroxides to Investigate Enzymatic Hydrolysis of Fatty Acids by Lipases Using Electron Paramagnetic Resonance in Turbid Media
Published in Analytical chemistry (Washington) (07-05-2019)“…While optical methods are not efficient enough for the easy, fast, and efficient detection of enzymatic activity in turbid media, the properties of the…”
Get full text
Journal Article -
10
Inhaled Gold Nano‐Star Carriers for Targeted Delivery of Triple Suicide Gene Therapy and Therapeutic MicroRNAs to Lung Metastases: Development and Validation in a Small Animal Model
Published in Advanced therapeutics (01-08-2022)“…Pulmonary metastases pose treatment challenges for many cancers, including triple‐negative breast cancer (TNBC). A novel suicide gene and therapeutic microRNAs…”
Get full text
Journal Article -
11
Selective On/Off‐Nitroxides as Radical Probes to Investigate Non‐radical Enzymatic Activity by Electron Paramagnetic Resonance
Published in Chemistry : a European journal (28-05-2018)“…A nitroxide carrying a peptide specific to the binding pocket of the serine proteases chymotrypsin and cathepsin G is prepared. This peptide is attached as an…”
Get full text
Journal Article -
12
An elastase activity reporter for Electronic Paramagnetic Resonance (EPR) and Overhauser-enhanced Magnetic Resonance Imaging (OMRI) as a line-shifting nitroxide
Published in Free radical biology & medicine (01-10-2018)“…Pulmonary inflammatory diseases are a major burden worldwide. They have in common an influx of neutrophils. Neutrophils secrete unchecked proteases at…”
Get full text
Journal Article -
13
An elastase activity reporter for Electronic Paramagnetic Resonance (EPR) and Overhauser-enhanced Magnetic Resonance Imaging (OMRI) as a line-shifting nitroxide
Published in Free radical biology & medicine (2018)“…Pulmonary inflammatory diseases are a major burden worldwide. They have in common an influx of neutrophils. Neutrophils secrete unchecked proteases at…”
Get full text
Journal Article