Search Results - "Juffre, Alexandria"
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Kidney-specific KO of the circadian clock protein PER1 alters renal Na + handling, aldosterone levels, and kidney/adrenal gene expression
Published in American journal of physiology. Renal physiology (01-04-2022)“…PERIOD 1 (PER1) is a circadian clock transcription factor that is regulated by aldosterone, a hormone that increases blood volume and Na retention to increase…”
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Regulation of Edn1 by Its Antisense Long Non-Coding RNA, Edn1-AS: SA-PO769
Published in Journal of the American Society of Nephrology (01-11-2022)Get full text
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Sex-specific differences in kidney clock gene expression in mice in response to a low potassium, high salt diet
Published in Physiology (Bethesda, Md.) (01-05-2023)“…Abstract only Clinical studies demonstrate that women have exacerbated salt-sensitive blood pressure (BP) responses compared to men. However, most studies…”
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Circadian Clocks of the Kidney: Function, Mechanism, and Regulation
Published in Physiological reviews (01-10-2022)“…An intrinsic cellular circadian clock is located in nearly every cell of the body. The peripheral circadian clocks within the cells of the kidney contribute to…”
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Adrenal-Specific Knockout of the Circadian Clock Protein BMAL1 Alters Kidney Clock Gene Expression: TH-PO327
Published in Journal of the American Society of Nephrology (01-11-2022)Get full text
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Renal tubular SGK1 is required to achieve blood pressure surge and circadian rhythm
Published in American journal of physiology. Renal physiology (01-11-2023)“…Blood pressure (BP) follows a circadian pattern that rises during the active phase of the day (morning surge) and decreases during the inactive (night dipping)…”
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Adrenal-Kidney Clock Crosstalk: Utilizing Tissue-Specific Clock KO Models
Published in Physiology (Bethesda, Md.) (01-05-2023)“…Abstract only Circadian rhythms are 24-hour oscillations that regulate many physiological functions including hormone signaling and electrolyte excretion…”
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A Role for the Adrenal Clock in Renin-Angiotensin-Aldosterone System Regulation: TH-PO326
Published in Journal of the American Society of Nephrology (01-11-2022)Get full text
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Abstract 096: Adrenal-specific KO Of The Circadian Clock Protein Bmal1 Alters Blood Pressure Rhythm
Published in Hypertension (Dallas, Tex. 1979) (01-09-2022)“…Abstract only BMAL1 is a core circadian clock protein that regulates most physiological functions, including blood pressure (BP). Global BMAL1 knockout (KO)…”
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Knockout of the Circadian Clock Protein PER1 (Period1) Exacerbates Hypertension and Increases Kidney Injury in Dahl Salt-Sensitive Rats
Published in Hypertension (Dallas, Tex. 1979) (01-11-2022)“…Circadian rhythms play an essential role in physiological function. The molecular clock that underlies circadian physiological function consists of a core…”
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Kidney‐Specific BMAL1 Knockout is Protective in High Salt Diet‐Induced Renal Inflammation
Published in The FASEB journal (01-05-2022)“…The circadian clock factor BMAL1, particularly within the kidney, has been shown to influence systemic blood pressure (BP) control. A diet high in salt is…”
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Global PER1 knockout Dahl Salt Sensitive rats show increased expression of renal Edn1 mRNA and Endothelin‐1 peptide
Published in The FASEB journal (01-05-2022)“…Background Previously, we showed that global knockout of the circadian clock protein PERIOD1 (PER1) in Dahl Salt Sensitive (SS) rats resulted in worsening of…”
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A Role for the Adrenal Clock in Aldosterone Regulation and Renal Excretory Function
Published in The FASEB journal (01-05-2022)“…Purpose of study It is well documented that most physiological functions, including hormone secretion, renal electrolyte excretion and blood pressure (BP),…”
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Male kidney-specific BMAL1 knockout mice are protected from K + -deficient, high-salt diet-induced blood pressure increases
Published in American journal of physiology. Renal physiology (01-11-2023)“…The circadian clock protein basic helix-loop-helix aryl hydrocarbon receptor nuclear translocator-like protein 1 (BMAL1) is a transcription factor that impacts…”
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The circadian clock protein PER1 is important in maintaining endothelin axis regulation in Dahl salt-sensitive rats
Published in Canadian journal of physiology and pharmacology (01-03-2023)“…Endothelin-1 (ET-1) is a peptide hormone that acts on its receptors to regulate sodium handling in the kidney's collecting duct. Dysregulation of the…”
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Adrenal-Specific KO of the Circadian Clock Protein BMAL1 Alters Blood Pressure Rhythm and Timing of Eating Behavior
Published in Function (Oxford, England) (2023)“…Abstract Brain and muscle ARNT-like 1 (BMAL1) is a core circadian clock protein and transcription factor that regulates many physiological functions, including…”
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Circadian Rhythm Effects on the Molecular Regulation of Physiological Systems
Published in Comprehensive Physiology (29-12-2021)“…Nearly every system within the body contains an intrinsic cellular circadian clock. The circadian clock contributes to the regulation of a variety of…”
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