Search Results - "Juffermans, Nicole P"

Transfusion-related acute lung injury: a clinical review by Vlaar, Alexander PJ, Dr, Juffermans, Nicole P, MD

“…Summary Three decades ago, transfusion-related acute lung injury (TRALI) was considered a rare complication of transfusion medicine. Nowadays, the US Food and…”
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Mechanisms of red blood cell transfusion‐related immunomodulation by Remy, Kenneth E., Hall, Mark W., Cholette, Jill, Juffermans, Nicole P., Nicol, Kathleen, Doctor, Allan, Blumberg, Neil, Spinella, Philip C., Norris, Philip J., Dahmer, Mary K., Muszynski, Jennifer A.

“…Red blood cell (RBC) transfusion is common in critically ill, postsurgical, and posttrauma patients in whom both systemic inflammation and immune suppression…”
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Four-factor prothrombin complex concentrate in trauma patients by Bouzat, Pierre, Hunt, Beverley J., Juffermans, Nicole P.

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A consensus redefinition of transfusion‐related acute lung injury by Vlaar, Alexander P.J., Toy, Pearl, Fung, Mark, Looney, Mark R., Juffermans, Nicole P., Bux, Juergen, Bolton‐Maggs, Paula, Peters, Anna L., Silliman, Christopher C., Kor, Daryl J., Kleinman, Steve

“…BACKGROUND Transfusion‐related acute lung injury (TRALI) is a serious complication of blood transfusion and is among the leading causes of transfusion‐related…”
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Ten tips on fever by Leone, Marc, Juffermans, Nicole P., Nielsen, Nathan D.

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Targeting Endothelial Dysfunction in Acute Critical Illness to Reduce Organ Failure by Juffermans, Nicole P ., van den Brom, Charissa E., Kleinveld, Derek J. B.

“…During hyperinflammatory conditions that can occur in acute critical illness, such as shock or hypoperfusion, inflammatory mediators activate the endothelium,…”
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The S100A10 Pathway Mediates an Occult Hyperfibrinolytic Subtype in Trauma Patients by Gall, Lewis S., Vulliamy, Paul, Gillespie, Scarlett, Jones, Timothy F., Pierre, Rochelle S. J., Breukers, Sabine E., Gaarder, Christine, Juffermans, Nicole P., Maegele, Marc, Stensballe, Jakob, Johansson, Pär I., Davenport, Ross A., Brohi, Karim

“…OBJECTIVE:To determine the characteristics of trauma patients with low levels of fibrinolysis as detected by viscoelastic hemostatic assay (VHA) and explore…”
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ICM experimental is growing, from bench via bedside to big data—and back by Juffermans, Nicole P.

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Prevalence, predictors and outcome of hypofibrinogenaemia in trauma: a multicentre observational study by Hagemo, Jostein S, Stanworth, Simon, Juffermans, Nicole P, Brohi, Karim, Cohen, Mitchell, Johansson, Pär I, Røislien, Jo, Eken, Torsten, Næss, Paal A, Gaarder, Christine

“…Exsanguination due to trauma-induced coagulopathy is a continuing challenge in emergency trauma care. Fibrinogen is a crucial factor for haemostatic…”
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iTACTIC - implementing Treatment Algorithms for the Correction of Trauma-Induced Coagulopathy: study protocol for a multicentre, randomised controlled trial by Baksaas-Aasen, Kjersti, Gall, Lewis, Eaglestone, Simon, Rourke, Claire, Juffermans, Nicole P, Goslings, J Carel, Naess, Paal Aksel, van Dieren, Susan, Ostrowski, Sisse Rye, Stensballe, Jakob, Maegele, Marc, Stanworth, Simon J, Gaarder, Christine, Brohi, Karim, Johansson, Per I

“…Traumatic injury is the fourth leading cause of death globally. Half of all trauma deaths are due to bleeding and most of these will occur within 6 h of…”
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Response to "Co-infections in COVID-19 critically ill and antibiotic management: a prospective cohort analysis" by Nieuwenhuis, Marieke B, Van Biesen, Stefaan, Juffermans, Nicole P

“…During the period of March 12 to July 27, 2020, 83 consecutive patients were admitted to the intensive care unit (ICU) of our teaching hospital in Amsterdam,…”
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Addressing gender imbalance in intensive care by Vincent, Jean-Louis, Juffermans, Nicole P, Burns, Karen E A, Ranieri, V Marco, Pourzitaki, Chryssa, Rubulotta, Francesca

“…There is a large gender gap in critical care medicine with women underrepresented, particularly in positions of leadership. Yet gender diversity better…”
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Transfusion of female blood in a rat model is associated with red blood cells entrapment in organs by Alshalani, Abdulrahman, de Wissel, Marit B, Tuip-de Boer, Anita M, Roelofs, Joris J. T. H, van Bruggen, Robin, Acker, Jason P, Juffermans, Nicole P

“…Transfusion of red blood cells (RBCs) has been associated with adverse outcomes. Mechanisms may be related to donor sex and biological age of RBC. This study…”
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Description of mitochondrial oxygen tension and its variability in healthy volunteers by Baysan, Meryem, Broere, Mark, Wille, Maarten E, Bergsma, Jule E, Mik, Egbert G, Juffermans, Nicole P, Tsonaka, Roula, van der Bom, Johanna G, Arbous, Sesmu M

“…Describing mitochondrial oxygenation (mitoPO2) and its within- and between-subject variability over time after 5-aminolevulinic acid (ALA) plaster application…”
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COVID-19: What we've done well and what we could or should have done better-the 4 Ps by Vincent, Jean-Louis, Wendon, Julia, Martin, Greg S, Juffermans, Nicole P, Creteur, Jacques, Cecconi, Maurizio

“…The current coronavirus pandemic has impacted heavily on ICUs worldwide. Although many hospitals and healthcare systems had plans in place to manage multiple…”
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Coagulopathy Underlying Rotational Thromboelastometry Derangements in Trauma Patients: A Prospective Observational Multicenter Study by Dujardin, Romein W. G., Kleinveld, Derek J. B., Gaarder, Christine, Brohi, Karim, Davenport, Ross A., Curry, Nicola, Stanworth, Simon, Johansson, Pär I., Stensballe, Jakob, Maegele, Marc, Juffermans, Nicole P.

“…Viscoelastic hemostatic assays such as rotational thromboelastometry (ROTEM®) are used to guide treatment of trauma induced coagulopathy. We hypothesized that…”
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Risk factors and outcome of transfusion-related acute lung injury in the critically ill: A nested case- control study by VLAAR, Alexander P. J, BINNEKADE, Jan M, PRINS, David, VAN STEIN, Danielle, HOFSTRA, Jorrit J, SCHULTZ, Marcus J, JUFFERMANS, Nicole P

“…To determine the incidence, risk factors, and outcome of transfusion-related acute lung injury in a cohort of critically ill patients. In a retrospective…”
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Effect of antibody-mediated connective tissue growth factor neutralization on lung edema in ventilator-induced lung injury in rats by van den Brom, Charissa E, Bozic, Caitlin, Polet, Chantal A, Bongers, Annabel, Tuip-de Boer, Anita M, Ibelings, Roselique, Roelofs, Joris J T H, Juffermans, Nicole P

“…Acute respiratory distress syndrome (ARDS) is characterized by alveolar edema that can progress to septal fibrosis. Mechanical ventilation can augment lung…”
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The incidence, risk factors, and outcome of transfusion-related acute lung injury in a cohort of cardiac surgery patients: a prospective nested case-control study by Vlaar, Alexander P.J., Hofstra, Jorrit J., Determann, Rogier M., Veelo, Denise P., Paulus, Frederique, Kulik, Wim, Korevaar, Johanna, de Mol, Bas A., Koopman, Marianne M.W., Porcelijn, Leendert, Binnekade, Jan M., Vroom, Margreeth B., Schultz, Marcus J., Juffermans, Nicole P.

“…Transfusion-related acute lung injury (TRALI) is the leading cause of transfusion-related morbidity and mortality. Both antibodies and bioactive lipids that…”
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Effect of transfusion of fresh frozen plasma on parameters of endothelial condition and inflammatory status in non-bleeding critically ill patients: a prospective substudy of a randomized trial by Straat, Marleen, Müller, Marcella C A, Meijers, Joost C M, Arbous, Mendi S, Spoelstra-de Man, Angelique M E, Beurskens, Charlotte J P, Vroom, Margreeth B, Juffermans, Nicole P

“…Much controversy exists on the effect of a fresh frozen plasma (FFP) transfusion on systemic inflammation and endothelial damage. Adverse effects of FFP have…”
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