Search Results - "Juergens, Guenther"
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Coagulation changes during presyncope and recovery
Published in PloS one (02-08-2012)“…Orthostatic stress activates the coagulation system. The extent of coagulation activation with full orthostatic load leading to presyncope is unknown. We…”
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Effects of nadroparin, enoxaparin, and unfractionated heparin on endogenous factor Xa and IIa formation and on thrombelastometry profiles
Published in Blood coagulation & fibrinolysis (01-01-2009)“…Measurements of anti-FXa or anti-FIIa (thrombin) activities are conventional tests for biological monitoring of low molecular weight heparin (LMWH) or…”
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Biochemical structural and functional properties of oxidized low-density lipoprotein
Published in Chemical research in toxicology (01-03-1990)“…Human low-density lipoprotein (LDL) is a main carrier for cholesterol in the blood stream. Cholesterol deposits in the arteries stem primarily from LDL…”
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Simvastatin Efficiently Lowers Small LDL-IgG Immune Complex Levels: A Therapeutic Quality beyond the Lipid-Lowering Effect
Published in PloS one (03-02-2016)“…We investigated a polyethylene glycol non-precipitable low-density lipoprotein (LDL) subfraction targeted by IgG and the influence of statin therapy on plasma…”
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Atorvastatin treatment increases plasma bilirubin but not HMOX1 expression in stable angina patients
Published in Scandinavian journal of clinical and laboratory investigation (01-09-2015)“…Abstract Background. In vitro and animal studies indicate that statins increase heme oxygenase-1 gene (HMOX1) expression, which then, presumably, increases…”
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Virtually same oxidizability of LDL but higher Lp(a) levels in arterial compared to venous plasma
Published in Chemistry and physics of lipids (01-12-2014)“…•We found the same basal oxidative status of arterial and venous LDL.•We found the same susceptibility of arterial and venous LDL to oxidation.•We found…”
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Stent implantation in the superficial femoral artery: Short thrombelastometry-derived coagulation times identify patients with late in-stent restenosis
Published in Thrombosis research (01-09-2012)“…Abstract Introduction The mechanisms of restenosis, the recurrence of luminal narrowing, are complex and incompletely understood to date. Thrombin, the pivotal…”
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Increased phosphatidylethanolamine N-methyltransferase gene expression in non-small-cell lung cancer tissue predicts shorter patient survival
Published in Oncology letters (01-06-2014)“…Lipid mobilization is of great importance for tumor growth and studies have suggested that cancer cells exhibit abnormal choline phospholipid metabolism. In…”
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In vitro oxidation of LDL by ozone
Published in Chemistry and physics of lipids (01-10-2014)“…•We show that ozone is capable of oxidizing low-density lipoprotein (LDL).•LPO, TBARS, REM, and oxidation-specific epitopes increase upon LDL oxidation by…”
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Collagen/endogenous thrombin-induced platelet aggregation in cord versus adult whole blood
Published in Neonatology (Basel, Switzerland) (01-01-2009)“…In previous studies, neonatal platelets have been shown to be hypoaggregable to various agonists when compared with adult platelets. It was the aim of this…”
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Cardiac catheterization: haemostatic changes in pediatric versus adult patients
Published in Journal of thrombosis and thrombolysis (01-10-2011)“…Thrombophilic or haemorrhagic complications are possible adverse events following cardiac catheterization particularly in pediatric patients. It was therefore…”
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Effects of nadroparin, enoxaparin, and unfractionated heparin on endogenous formation of factor Xa and IIa and on thrombelastometry profiles in cord versus adult blood
Published in Neonatology (Basel, Switzerland) (01-01-2011)“…To date, only few pharmacokinetic studies on low-molecular-weight heparins (LMWHs) in neonates exist not allowing to formally assess pharmacodynamics of LMWHs…”
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Energy status of pig donor organs after ischemia is independent of donor type
Published in The Journal of surgical research (01-04-2013)“…Abstract Background Literature is controversial whether organs from living donors have a better graft function than brain dead (BD) and non–heart-beating donor…”
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Heparinase-modified thrombelastometry: inactivation of heparin in plasma samples
Published in Clinical laboratory (Heidelberg) (2010)“…The heparinase-modified thrombelastometry (HEPTEM) assay is a promising tool to assess the coagulation status of heparinised patients. The aim of our study was…”
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Improved myocardial protection in the failing heart by selective endothelin-A receptor blockade
Published in The Journal of thoracic and cardiovascular surgery (01-04-2009)“…Objective Ischemia/reperfusion injury caused by cardioplegic arrest is still a major challenge in patients with reduced left ventricular function. We…”
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The Pleiotropic Effects of Atorvastatin on Stable Angina Patients: Evidence by Analysis of High-Density Lipoprotein Size and Subclasses, and Plasma mRNA
Published in Journal of medical biochemistry (01-07-2015)“…High-density lipoproteins (HDL) have athero-protective biological properties: antioxidative, anti-apoptotic, anti-inflammatory, and they have the efflux…”
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Protein S modulates the anticoagulant action of recombinant human activated protein C: a comparison between neonates and adults
Published in British journal of pharmacology (01-12-2005)“…Recombinant human‐activated protein C (rhAPC, Drotrecogin alpha (activated), Xigris™) has been shown to reduce organ damage and decrease mortality in severe…”
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High availability of intravascular tissue factor in neonates
Published in Journal of pediatric hematology/oncology (01-05-2007)“…In the present study, we compared the levels of intravascular tissue factor (TF) present in cord versus adult whole blood (WB) prior and after…”
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