Search Results - "Judge, Thomas M"

Differentiation of antiinflammatory and antitumorigenic properties of stabilized enantiomers of thalidomide analogs by Jacques, Vincent, Czarnik, Anthony W., Judge, Thomas M., Van der Ploeg, Lex H. T., DeWitt, Sheila H.

“…Therapeutics developed and sold as racemates can exhibit a limited therapeutic index because of side effects resulting from the undesired enantiomer (distomer)…”
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A Facile Asymmetric Synthesis of 1,2,3-Substituted Indenes by Romines, Karen R, Lovasz, Kristine D, Mizsak, Stephen A, Morris, Jeanette K, Seest, Eric P, Han, Fusen, Tulinsky, John, Judge, Thomas M, Gammill, Ronald B

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2-Aryl-2-hydroxyethylamine substituted 4-oxo-4,7-dihydrothieno[2,3- b]pyridines as broad-spectrum inhibitors of human herpesvirus polymerases by Schnute, Mark E., Anderson, David J., Brideau, Roger J., Ciske, Fred L., Collier, Sarah A., Cudahy, Michele M., Eggen, MariJean, Genin, Michael J., Hopkins, Todd A., Judge, Thomas M., Kim, Euibong J., Knechtel, Mary L., Nair, Sajiv K., Nieman, James A., Oien, Nancee L., Scott, Allen, Tanis, Steven P., Vaillancourt, Valerie A., Wathen, Michael W., Wieber, Janet L.

“…A potent series of broad-spectrum antivirals against human herpesviruses has been identified which inhibit HCMV, HSV-1, EBV, and VZV polymerases. A novel…”
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Asymmetric Synthesis of an HIV Protease Inhibitor via a Novel .alpha.-Oxoketene/Ketene [4 + 2] Cycloaddition Reaction by Gammill, Ronald B, Judge, Thomas M, Phillips, Gillian, Zhang, Qingwei, Sowell, C. Gregory, Cheney, B. Vernon, Mizsak, Stephen A, Dolak, Lester A, Seest, Eric P

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Synthesis and biological evaluation of antiplatelet 2-aminochromones by Morris, Joel, Wishka, Donn G, Lin, Alice H, Humphrey, William R, Wiltse, Ann L, Gammill, Ronald B, Judge, Thomas M, Bisaha, Sharon N, Olds, Nancy L

“…The synthesis and biological evaluation of a series of antiplatelet 2-morpholinylchromones has been described. Modification of the C-7 phenylmethoxy group of…”
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Structure-Based Design of HIV Protease Inhibitors:  Sulfonamide-Containing 5,6-Dihydro-4-hydroxy-2-pyrones as Non-Peptidic Inhibitors by Thaisrivongs, Suvit, Skulnick, Harvey I, Turner, Steve R, Strohbach, Joseph W, Tommasi, Ruben A, Johnson, Paul D, Aristoff, Paul A, Judge, Thomas M, Gammill, Ronald B, Morris, Jeanette K, Romines, Karen R, Chrusciel, Robert A, Hinshaw, Roger R, Chong, Kong-Teck, Tarpley, W. Gary, Poppe, Susan M, Slade, David E, Lynn, Janet C, Horng, Miao-Miao, Tomich, Paul K, Seest, Eric P, Dolak, Lester A, Howe, W. Jeffrey, Howard, Gina M, Schwende, Francis J, Toth, Lisa N, Padbury, Guy E, Wilson, Grace J, Shiou, Lihua, Zipp, Gail L, Wilkinson, Karen F, Rush, Bob D, Ruwart, Mary J, Koeplinger, Kenneth A, Zhao, Zhiyang, Cole, Serena, Zaya, Renee M, Kakuk, Thomas J, Janakiraman, Musiri N, Watenpaugh, Keith D

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Light-induced, iodine-catalyzed aerobic oxidation of unsaturated tertiary amines by Gangloff, Anthony R, Judge, Thomas M, Helquist, Paul

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A titanium (IV) mediated one-pot double condensation synthesis of 5,6-dihydro-4 H-pyran-4-ones by Morris, Joel, Wishka, Donn G., Luke, George P., Judge, Thomas M., Gammill, Ronald B.

“…An alternative method for the synthesis of 2-amino-5,6-dihydro-4 H-pyran-4-ones and 5,6-dihydro-4 H-pyran-4-ones is described. This preparation makes use of…”
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A titanium (IV) mediated one-pot double condensation synthesis of 5,6-dihydro-4H-pyran-4-ones by Morris, Joel, Wishka, Donn G., Luke, George P., Judge, Thomas M., Gammill, Ronald B.

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U-93631 causes rapid decay of gamma-aminobutyric acid-induced chloride currents in recombinant rat gamma-aminobutyric acid type A receptors by Dillon, G H, Im, H K, Hamilton, B J, Carter, D B, Gammill, R B, Judge, T M, Im, W B

“…We discovered the ability of U-93631 (4-dimethyl-3-t-butylcarboxyl-4,5- dihydro[1,5-a]imidazoquinoxaline) to accelerate decay of gamma-aminobutyric acid…”
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