Search Results - "Judge, A R"

p38 MAPK links oxidative stress to autophagy-related gene expression in cachectic muscle wasting by McClung, J M, Judge, A R, Powers, S K, Yan, Z

“…Oxidative stress is a primary trigger of cachectic muscle wasting, but the signaling pathway(s) that links it to the muscle wasting processes remains to be…”
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Calpain-1 is required for hydrogen peroxide-induced myotube atrophy by McClung, J M, Judge, A R, Talbert, E E, Powers, S K

“…Recent reports suggest numerous roles for cysteine proteases in the progression of skeletal muscle atrophy due to disuse or disease. Nonetheless, a specific…”
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Cancer cachexia decreases specific force and accelerates fatigue in limb muscle by Roberts, B.M., Frye, G.S., Ahn, B., Ferreira, L.F., Judge, A.R.

“…•C-26 cancer cachexia causes a significant decrease in limb muscle absolute force.•C-26 cancer cachexia causes a significant decrease in limb muscle specific…”
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Rapid diaphragm atrophy following cervical spinal cord hemisection by Gill, L.C, Ross, H.H, Lee, K.Z, Gonzalez-Rothi, E.J, Dougherty, B.J, Judge, A.R, Fuller, D.D

“…Highlights • Diaphragm tissue was harvested from Sprague-Dawley rats 1 or 7 days following cervical (C2) hemilesion (C2Hx). • Histological analysis…”
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Xanthine oxidase and activated neutrophils cause oxidative damage to skeletal muscle after contractile claudication by Judge, A R, Dodd, S L

“…We previously showed oxidative damage and edema within skeletal muscle after contractile claudication. To investigate the sources of this oxidative damage in…”
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Antioxidants attenuate oxidative damage in rat skeletal muscle during mild ischaemia by Judge, A. R., Selsby, J. T., Dodd, S. L.

“…We have previously shown oxidative stress and oedema, caused by both xanthine oxidase-derived oxidants and infiltrating neutrophils, within skeletal muscle…”
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Oxidative damage to skeletal muscle following an acute bout of contractile claudication by Judge, A.R, Dodd, S.L

“…The purpose of this study was to determine the extent and sources of oxidative stress within skeletal muscle following an acute bout of contractile…”
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Synchrotron X-ray reciprocal-space mapping, topography and diffraction resolution studies of macromolecular crystal quality by Boggon, T. J., Helliwell, J. R., Judge, R. A., Olczak, A., Siddons, D. P., Snell, E. H., Stojanoff, V.

“…A comprehensive study of microgravity and ground‐grown chicken egg‐white lysozyme crystals is presented using synchrotron X‐ray reciprocal‐space mapping,…”
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Inhibition of IkappaB kinase alpha (IKKα) or IKKbeta (IKKβ) plus forkhead box O (Foxo) abolishes skeletal muscle atrophy by Reed, S.A., Senf, S.M., Cornwell, E.W., Kandarian, S.C., Judge, A.R.

“…► Independent inhibition of Foxo, IKKα and IKKβ activities does not alter muscle fiber size in weight bearing muscles. ► Inhibition of Foxo activity plus IKKα…”
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The effect of protein impurities on lysozyme crystal growth by Judge, Russell A., Forsythe, Elizabeth L., Pusey, Marc L.

“…While bulk crystallization from impure solutions is used industrially as a purification step for a wide variety of materials, it is a technique that has rarely…”
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The Effect of Temperature and Solution pH on the Nucleation of Tetragonal Lysozyme Crystals by Judge, Russell A., Jacobs, Randolph S., Frazier, Tyralynn, Snell, Edward H., Pusey, Marc L.

“…Part of the challenge of macromolecular crystal growth for structure determination is obtaining crystals with a volume suitable for x-ray analysis. In this…”
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Tetragonal Chicken Egg White Lysozyme Solubility in Sodium Chloride Solutions by Forsythe, Elizabeth L, Judge, Russell A, Pusey, Marc L

“…The solubility of chicken egg white lysozyme crystallized in the tetragonal form was measured in sodium chloride solutions from 1.6 to 30.7 °C, using a…”
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C73 OXIDANTS: Diaphragm Abnormalities In Heart Failure Patients: Upregulation Of Nad(p)h Oxidase Subunits And Heightened Protein Oxidation by Ferreira, L F, Ahn, B, Beharry, A W, Coblentz, P D, Patel, N, Judge, A R, Bonnell, M R, Hoopes, C W

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Solubility of Ovalbumin in Ammonium Sulfate Solutions by Judge, Russell A, Johns, Michael R, White, Edward T

“…The solubilities of the protein ovalbumin in aqueous ammonium sulfate solutions ranging from 18 to 30 g ammonium sulfate/100 g water at 30 °C were determined…”
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Biology of Activating Transcription Factor 4 (ATF4) and Its Role in Skeletal Muscle Atrophy by Ebert, Scott M, Rasmussen, Blake B, Judge, Andrew R, Judge, Sarah M, Larsson, Lars, Wek, Ronald C, Anthony, Tracy G, Marcotte, George R, Miller, Matthew J, Yorek, Mark A, Vella, Adrian, Volpi, Elena, Stern, Jennifer I, Strub, Matthew D, Ryan, Zachary, Talley, John J, Adams, Christopher M

“…Activating transcription factor 4 (ATF4) is a multifunctional transcription regulatory protein in the basic leucine zipper superfamily. ATF4 can be expressed…”
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XANTHINE OXIDASE AND NEUTROPHILS ARE ELEVATED FOLLOWING A SHORT BOUT OF CONTRACTILE-INDUCED MUSCLE ISCHEMIA by Judge, A R., Dodd, S L.

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OXIDATIVE STRESS IS ASSOCIATED WITH CONTRACTILE-INDUCED SKELETAL MUSCLE ISCHEMIA by Judge, A R., Dodd, S L.

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Life long calorie restriction increases heat shock proteins and proteasome activity in soleus muscles of Fisher 344 rats by Selsby, Joshua T., Judge, Andrew R., Yimlamai, Tossaporn, Leeuwenburgh, Christiaan, Dodd, Stephen L.

“…Heat shock proteins (HSP's) closely interact with 20S proteasome and have been shown to maintain catalytic activity, responsible for the prevention of protein…”
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Microgravity and Macromolecular Crystallography by Kundrot, Craig E, Judge, Russell A, Pusey, Marc L, Snell, Edward H

“…Macromolecular crystal growth is seen as an ideal experiment to make use of the reduced acceleration environment provided by an orbiting spacecraft. The…”
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Acute efficacy of fluoxetine versus sertraline and paroxetine in major depressive disorder including effects of baseline insomnia by FAVA, Maurizio, HOOG, Sharon L, JUDGE, Rajinder A, KOPP, Joan B, NILSSON, Mary E, GONZALES, Jill S

“…This study assessed whether fluoxetine, sertraline, and paroxetine differ in efficacy and tolerability in depressed patients and the impact of baseline…”
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