Search Results - "Judd, Robert L."

Anti-inflammatory effects of the hydroxycarboxylic acid receptor 2 by Graff, Emily C, Fang, Han, Wanders, Desiree, Judd, Robert L

“…Abstract The hydroxycarboxylic acid receptors (HCA1–3 ) are a family of G-protein-coupled receptors that are critical for sensing endogenous intermediates of…”
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Effects of high fat diet on GPR109A and GPR81 gene expression by Wanders, Desiree, Graff, Emily C., Judd, Robert L.

“…► High fat diet reduces adipose tissue gene expression of GPR109A and GPR81. ► GPR109A and GPR81 are positively correlated with PPARγ gene expression in fat. ►…”
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Role of HCA2 in Regulating Intestinal Homeostasis and Suppressing Colon Carcinogenesis by Li, Zhuoyue, McCafferty, Kayleen J., Judd, Robert L.

“…Hydroxycarboxylic acid receptor 2 (HCA 2 ) is vital for sensing intermediates of metabolism, including β-hydroxybutyrate and butyrate. It also regulates…”
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Metabolic phenotype and adipose and liver features in a high-fat Western diet-induced mouse model of obesity-linked NAFLD by Luo, Yuwen, Burrington, Christine M, Graff, Emily C, Zhang, Jian, Judd, Robert L, Suksaranjit, Promporn, Kaewpoowat, Quanhathai, Davenport, Samantha K, O'Neill, Ann Marie, Greene, Michael W

“…nonalcoholic fatty liver disease (NAFLD), an obesity and insulin resistance associated clinical condition - ranges from simple steatosis to nonalcoholic…”
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Niacin increases adiponectin and decreases adipose tissue inflammation in high fat diet-fed mice by Wanders, Desiree, Graff, Emily C, White, B Douglas, Judd, Robert L

“…To determine the effects of niacin on adiponectin and markers of adipose tissue inflammation in a mouse model of obesity. Male C57BL/6 mice were placed on a…”
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The Absence of Adiponectin Alters Niacin's Effects on Adipose Tissue Inflammation in Mice by Graff, Emily C, Fang, Han, Wanders, Desiree, Judd, Robert L

“…Obesity is an immunometabolic disease associated with chronic inflammation and the dysregulation of pro- and anti-inflammatory cytokines. One hallmark of…”
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Niacin stimulates adiponectin secretion through the GPR109A receptor by Plaisance, Eric P, Lukasova, Martina, Offermanns, Stefan, Zhang, Youyan, Cao, Guoqing, Judd, Robert L

“…Niacin (nicotinic acid) has recently been shown to increase serum adiponectin concentrations in men with the metabolic syndrome. However, little is known about…”
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Insulin treatment prevents diabetes-induced alterations in astrocyte glutamate uptake and GFAP content in rats at 4 and 8 weeks of diabetes duration by Coleman, Elaine S, Dennis, John C, Braden, Timothy D, Judd, Robert L, Posner, Phil

“…Abstract Rat astrocyte function is changed by diabetes mellitus relative to the nondiabetic state and we believe that altered function contributes to the…”
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Whole-slide image analysis outperforms micrograph acquisition for adipocyte size quantification by Maguire, Anne S, Woodie, Lauren N, Judd, Robert L, Martin, Douglas R, Greene, Michael W, Graff, Emily C

“…The distinction between biological processes of adipose tissue expansion is crucial to understanding metabolic derangements, but a robust method for…”
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146-OR: Loss of Hydroxycarboxylic Acid Receptor 2 (HCA2) Affects Adipose Tissue Homeostasis in a Sex-Specific Manner during Prolonged Fasting by MCCAFFERTY, KAYLEEN J., BRINKER, EMILY, GRAFF, EMILY, STEURY, TODD D., GREENE, MICHAEL W., JUDD, ROBERT L.

“…Hydroxycarboxylic acid receptor 2 (HCA2) , formally known as GPR109A, is a metabolite-sensing receptor expressed predominately on adipocytes, immune cells and…”
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Pharmacological effects of lipid-lowering drugs on circulating adipokines by Wanders, Desiree, Plaisance, Eric P, Judd, Robert L

“…The cardioprotective effects of lipid-lowering drugs have been primarily attributed to their effects on blood lipid metabolism.However,emerging evidence…”
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306-OR: PEA15 Regulates Metabolism and Adiposity in a Sex-Dependent Manner through Alterations in Metabolic Flexibility by J. TOWNS, T., BRINKER, EMILY, WATANABE, RIE, ODENIYI, IFEOLUWA A., MCCAFFERTY, KAYLEEN J., GRABAU, NATASHA, KROEGER, DANIEL, GREENE, MICHAEL W., JUDD, ROBERT L., GRAFF, EMILY

“…Phosphoprotein enriched in astrocytes 15kDa (PEA15) is a ubiquitously expressed cytosolic protein with high expression in the brain, and enhanced expression in…”
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225-LB: Reciprocal Regulatory Interactions of Adipocytes and B Lymphocytes by BREWER, JOSEPH W., ALLMAN, MARY K., CARROLL, STEVEN R., GRANGER, SARAH, HALL, ALEXANDER, POWNALL, KEELEY, QUINTANA, JOSHUA, ARELLANO RANGEL, NANCY, THOMAS, JADE, JUDD, ROBERT L.

“…Obesity, a global health problem, leads to chronic inflammation of adipose tissue (AT), an immune-mediated process linked to metabolic dysfunction and disease,…”
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Niacin increases diet-induced hepatic steatosis in B6129 mice by Fang, Han, Li, Zhuoyue, Graff, Emily C., McCafferty, Kayleen J., Judd, Robert L.

“…Nonalcoholic fatty liver disease (NAFLD) is a very common disorder affecting between 20 and 30% of adults in the United States. However, there is no effective…”
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2473-PUB: Differential Effects of High-Fat Diet and Niacin on Nonalcoholic Fatty Liver Disease in C57BL/6J and B6129SF2/J Mice: A Metabolomic Analysis by FANG, HAN, LI, ZHUOYUE, GRAFF, EMILY, MCCAFFERTY, KAYLEEN J., JUDD, ROBERT L.

“…Recent studies have demonstrated significant metabolic changes in different strains of mice fed a high-fat diet (HFD). Pharmacological doses of niacin can…”
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Guanethidine treatment does not block the ability of central leptin administration to decrease blood glucose concentrations in streptozotocin-induced diabetic rats by Wang, Jinpin, Wernette, Catherine M, Judd, Robert L, Huggins, Kevin W, White, B Douglas

“…Leptin, administered either into the ventricles of the brain or systemically, has been shown to normalize blood glucose concentrations in streptozotocin…”
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Culture and Sampling of Primary Adipose Tissue in Practical Microfluidic Systems by Brooks, Jessica C, Judd, Robert L, Easley, Christopher J

“…Microfluidic culture of primary adipose tissue allows for reduced sample and reagent volumes as well as constant media perfusion of the cells. By continuously…”
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Regulation of intracellular trafficking and secretion of adiponectin by myosin II by Bedi, Deepa, Dennis, John C., Morrison, Edward E., Braden, Tim D., Judd, Robert L.

“…Adiponectin is a protein secreted by white adipocytes that plays an important role in insulin action, energy homeostasis and the development of…”
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Changes in hepatic phase I and phase II biotransformation enzyme expression and glutathione levels following atrazine exposure in female rats by Zimmerman, Arthur D., Breckenridge, Charles B., Yi, Kun D., Sawhney Coder, Pragati, Wanders, Desiree, Judd, Robert L., Foradori, Chad D.

“…1. To determine the effects of repeated atrazine (ATR) treatment on hepatic phase I and II enzymes, adult female rats were treated with vehicle or 100 mg/kg of…”
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A microfluidic interface for the culture and sampling of adiponectin from primary adipocytes by Godwin, Leah A, Brooks, Jessica C, Hoepfner, Lauren D, Wanders, Desiree, Judd, Robert L, Easley, Christopher J

“…Secreted from adipose tissue, adiponectin is a vital endocrine hormone that acts in glucose metabolism, thereby establishing its crucial role in diabetes,…”
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