Search Results - "Jubilut, Guita N"
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Evaluation of 4-tert-Butyl-Benzhydrylamine Resin (BUBHAR) as an Alternative Solid Support for Peptide Synthesis
Published in International journal of polymer science (2020)“…Following preliminary reports that introduced 4-tert-butylbenzhydrylamine resin (BUBHAR) as a novel polymer for use in solid-phase peptide chemistry (SPPS),…”
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2
Novel copoly(styrene-divinylbenzene)-resins with different phenylmethylamine groups for use in Peptide synthesis method
Published in Protein and peptide letters (01-01-2015)“…Differently than the 4-methylbenzhydrylamine-resin (MBHAR) which contains a methyl group coupled to the phenylmethylamine-functionalized…”
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3
Determination of Site−Site Distance and Site Concentration within Polymer Beads: A Combined Swelling-Electron Paramagnetic Resonance Study
Published in Journal of organic chemistry (10-06-2005)“…This work proposes a combined swelling-electron paramagnetic resonance (EPR) approach aiming at determining some unusual polymer solvation parameters relevant…”
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4
Evaluation of the Trifluoromethanosulfonic Acid/Trifluoroacetic Acid/Thioanisole Cleavage Procedure for Application in Solid-Phase Peptide Synthesis
Published in Chemical & pharmaceutical bulletin (2001)“…As an extension of our investigation of peptidyl-resin linkage stability towards different cleavage procedures used in the solid-phase peptide synthesis (SPPS)…”
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5
Solid-phase peptide synthesis in highly loaded conditions
Published in Bioorganic chemistry (01-04-2011)“…HPLC profiles of crude peptides synthesized in highly and in low loaded resins. [Display omitted] ► Selected peptide-resins were synthesized in low and highly…”
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6
Spectroscopic and structural analysis of somatic and N-domain angiotensin I-converting enzyme isoforms from mesangial cells from Wistar and spontaneously hypertensive rats
Published in International journal of biological macromolecules (01-08-2010)“…Angiotensin I-converting enzyme (ACE) plays a key role in the renin-angiotesin aldosterone cascade. We analysed the secondary structure and structural…”
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7
Gamma Ray Irradiation of the Vasoactive Peptide Bradykinin Reveals a Residue- and Position-Dependent Structural Modification
Published in International journal of peptide research and therapeutics (01-06-2010)“…In this work the effect of radical species generated by gamma ray irradiation of aqueous solution upon structure of vasoactive peptide bradykinin (BK,…”
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Resin Selection Based on the Lability of Peptidyl-Resin Linkage towards HF and TFA Steps : Dependence on the C-Terminal Amino Acid and Peptide Length
Published in Chemical & pharmaceutical bulletin (1999)“…Ideally, the solid support used for tert-butyloxycarbonyl (Boc)-peptide synthesis method must allow sufficient stability of the peptide linkage towards…”
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9
Monitoring the Chemical Assembly of a Transmembrane Bradykinin Receptor Fragment: Correlation Between Resin Solvation, Peptide Chain Mobility, and Rate of Coupling
Published in European journal of organic chemistry (01-11-2002)“…A combined resin solvation‐peptide chain motion and kinetics of coupling reaction approach was applied to monitor details of the synthesis of TM‐34, a…”
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10
A Proposed EPR Approach to Evaluating Agonist Binding Site of a Peptide Receptor
Published in International journal of peptide research and therapeutics (01-06-2008)“…Angiotensin II (Ang II) and its transmembrane AT 1 receptor were selected in order to test an innovative strategy that might allow the assessment of the…”
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11
Importance of the solvation degree of peptide-resin beads for amine groups determination by the picric acid method
Published in Journal of the Brazilian Chemical Society (01-01-2000)“…The classic and important picric acid method used in polymers biochemical and chemical fields of polymers for amine group quantification was chosen in this…”
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12
Bradykinin metabolism pathway in the rat pulmonary circulation
Published in Journal of hypertension (01-12-1992)“…The contribution made by different enzymes to the degradation of bradykinin in physiological conditions was estimated by examining bradykinin metabolism in rat…”
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13
Use of the same polymer for synthesis and purification of peptides
Published in Journal of the Brazilian Chemical Society (01-04-2005)“…This work reveals an uncommon but valuable biotechnological approach regarding the use of a same polymer (benzhydrylamine-resin, BHAR) for synthesis and anion…”
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14
Resin Selection Based on the Lability of Peptidyl-Resin Linkage towards HF and TFA Steps
Published in Chemical & pharmaceutical bulletin (01-11-1999)“…Ideally, the solid support used for tert-butyloxycarbonyl (Boc)-peptide synthesis method must allow sufficient stability of the peptide linkage towards…”
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15
Comparative time-course study of aminoacyl- and dipeptidyl-resin hydrolysis
Published in Journal of the Brazilian Chemical Society (1997)“…The classic hydrolysis procedure for quantification of resin-bound aminoacyl and peptidyl groups with 12 N HCl: propionic acid was reevaluated by studying the…”
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