Search Results - "Juarez, Jose C"

Copper Binding by Tetrathiomolybdate Attenuates Angiogenesis and Tumor Cell Proliferation through the Inhibition of Superoxide Dismutase 1 by Jose C. Juarez, Oscar Betancourt, Jr, Steven R. Pirie-Shepherd, Xiaojun Guan, Melissa L. Price, David E. Shaw, Andrew P. Mazar, Fernando Doñate

“…Purpose: A second-generation tetrathiomolybdate analogue (ATN-224; choline tetrathiomolybdate), which selectively binds copper with high affinity, is currently…”
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Peptides derived from the histidine-proline domain of the histidine-proline-rich glycoprotein bind to tropomyosin and have antiangiogenic and antitumor activities by DONATE, Fernando, JUAREZ, Jose C, XIAOJUN GUAN, SHIPULINA, Natalya V, PLUNKETT, Marian L, TEL-TSUR, Ziva, SHAW, David E, MORGAN, William T, MAZAR, Andrew P

“…The antiangiogenic activity of the multidomain plasma protein histidine-proline-rich glycoprotein (HPRG) is localized to its histidine-proline-rich (H/P)…”
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Histidine-proline rich glycoprotein (HPRG) binds and transduces anti-angiogenic signals through cell surface tropomyosin on endothelial cells by Guan, Xiaojun, Juarez, Jose C, Qi, Xiaoping, Shipulina, Natalya V, Shaw, David E, Morgan, William T, McCrae, Keith R, Mazar, Andrew P, Doñate, Fernando

“…The anti-angiogenic properties of the histidine-proline-rich (H/P) domain of HPRG have recently been described (Juarez JC, et al. Cancer Research 2002; 62:…”
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The Antiangiogenic Activity of Cleaved High Molecular Weight Kininogen Is Mediated through Binding to Endothelial Cell Tropomyosin by Zhang, Jing-Chuan, Doñate, Fernando, Qi, Xiaoping, Ziats, Nicholas P., Juarez, Jose C., Mazar, Andrew P., Pang, Yuan-Ping, McCrae, Keith R.

“…Conformationally altered proteins and protein fragments derived from the extracellular matrix and hemostatic system may function as naturally occurring…”
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Superoxide Dismutase 1 (SOD1) Is Essential for H₂O₂-Mediated Oxidation and Inactivation of Phosphatases in Growth Factor Signaling by Juarez, Jose C., Manuia, Mari, Burnett, Mark E., Betancourt, Oscar, Boivin, Benoit, Shaw, David E., Tonks, Nicholas K., Mazar, Andrew P., Doñate, Fernando

“…Superoxide dismutase 1 (SOD1) is an abundant copper/zinc enzyme found in the cytoplasm that converts superoxide into hydrogen peroxide and molecular oxygen…”
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Histidine-proline-rich glycoprotein has potent antiangiogenic activity mediated through the histidine-proline-rich domain by JUAREZ, Jose C, XIAOJUN GUAN, MORGAN, William T, DONATE, Fernando, SHIPULINA, Natalya V, PLUNKETT, Marian L, PARRY, Graham C, SHAW, David Elliot, ZHANG, Jing-Chuan, RABBANI, Shafaat A, MCCRAE, Keith R, MAZAR, Andrew P

“…Histidine-proline-rich glycoprotein (HPRG) is an abundant multidomain plasma protein evolutionarily related to high-molecular-weight kininogen. The cleaved…”
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Synthesis and Evaluation of Multisubstrate Bicyclic Pyrimidine Nucleoside Inhibitors of Human Thymidine Phosphorylase by Allan, Amy L, Gladstone, Patricia L, Price, Melissa L. P, Hopkins, Stephanie A, Juarez, Jose C, Doñate, Fernando, Ternansky, Robert J, Shaw, David E, Ganem, Bruce, Li, Yingbo, Wang, Weiru, Ealick, Steven

“…A series of novel, multisubstrate, bicyclic pyrimidine nucleoside inhibitors of human thymidine phosphorylase (TP) is described. Thymidine phosphorylase has…”
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Design of novel N-(2,4-dioxo-1,2,3,4-tetrahydro-thieno[3,2- d]pyrimidin-7-yl)-guanidines as thymidine phosphorylase inhibitors, and flexible docking to a homology model by Price, MelissaL.P., Guida, WayneC, Jackson, TaraE, Nydick, JasonA, Gladstone, PatriciaL, Juarez, JoséC., Doñate, Fernando, Ternansky, RobertJ

“…A novel class of thymidine phosphorylase (TP) inhibitors has been designed based on analogy to the enzyme substrate as well as known inhibitors. Flexible…”
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Superoxide dismutase 1 (SOD1) is essential for H^sub 2^O^sub 2^-mediated oxidation and inactivation of phosphatases in growth factor signaling by Juarez, Jose C, Manuia, Mari, Burnett, Mark E, Betancourt, Oscar, Boivin, Benoit, Shaw, David E, Tonks, Nicholas K, Mazar, Andrew P, Doñate, Fernando

“…Superoxide dismutase 1 (SOD1) is an abundant copper/zinc enzyme found in the cytoplasm that converts superoxide into hydrogen peroxide and molecular oxygen…”
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Superoxide dismutase 1 (SOD1) is essential for H 2 O 2 -mediated oxidation and inactivation of phosphatases in growth factor signaling by Juarez, Jose C., Manuia, Mari, Burnett, Mark E., Betancourt, Oscar, Boivin, Benoit, Shaw, David E., Tonks, Nicholas K., Mazar, Andrew P., Doñate, Fernando

“…Superoxide dismutase 1 (SOD1) is an abundant copper/zinc enzyme found in the cytoplasm that converts superoxide into hydrogen peroxide and molecular oxygen…”
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Superoxide dismutase 1 (SOD1) is essential for H sub(2)O sub(2)-mediated oxidation and inactivation of phosphatases in growth factor signaling by Juarez, Jose C, Manuia, Mari, Burnett, Mark E, Betancourt, Oscar, Boivin, Benoit, Shaw, David E, Tonks, Nicholas K, Mazar, Andrew P, Donate, Fernando

“…Superoxide dismutase 1 (SOD1) is an abundant copper/zinc enzyme found in the cytoplasm that converts superoxide into hydrogen peroxide and molecular oxygen…”
Get full text