Search Results - "Juang, Shin‐Hun"
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4,4‐Diallyl curcumin bis(2,2‐hydroxymethyl)propanoate ameliorates nonalcoholic steatohepatitis in methionine‐choline‐deficient diet and Western diet mouse models
Published in Chemical biology & drug design (01-05-2024)“…Nonalcoholic steatohepatitis (NASH) is a progressive form of nonalcoholic fatty liver disease (NAFLD) that causes severe liver damage, fibrosis, and scarring…”
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2
Estrogen induces the expression of EBV lytic protein ZEBRA, a marker of poor prognosis in nasopharyngeal carcinoma
Published in Cancer science (01-08-2022)“…Several epidemiological studies have suggested that Epstein–Barr virus (EBV) lytic infection is essential for the development of nasopharyngeal carcinoma…”
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3
Genetic variants in microRNAs and microRNA target sites predict biochemical recurrence after radical prostatectomy in localized prostate cancer
Published in International journal of cancer (01-12-2014)“…Recent evidence indicates that microRNAs might participate in prostate cancer initiation, progression and treatment response. Germline variations in microRNAs…”
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4
Identification of antiproliferative emodin analogues as inhibitors of epidermal growth factor receptor in cancer
Published in International journal of molecular medicine (01-03-2019)“…A series of emodin analogues have been demonstrated to exhibit potent antiproliferative activity in three human epidermal growth factor receptor 2…”
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5
One-pot synthesis and antiproliferative evaluation of pyrazolo[3,4-d]pyrimidine derivatives
Published in Tetrahedron (25-11-2012)“…An efficient one-pot methodology for the synthesis of pyrazolo[3,4-d]pyrimidines was developed by using 5-aminopyrazoles with formamide in presence of PBr3 as…”
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6
Studies of Coumarin Derivatives for Constitutive Androstane Receptor (CAR) Activation
Published in Molecules (Basel, Switzerland) (31-12-2020)“…Constitutive androstane receptor (CAR) activation has found to ameliorate diabetes in animal models. However, no CAR agonists are available clinically…”
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7
The Constituents of the Stems of Cissus assamica and Their Bioactivities
Published in Molecules (Basel, Switzerland) (28-10-2018)“…Fifty-five compounds were isolated from the fresh stems of , including 14 benzenoids, 11 triterpenes, nine steroids, five tocopherols, five chlorophylls, four…”
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8
Polymorphisms inside MicroRNAs and MicroRNA Target Sites Predict Clinical Outcomes in Prostate Cancer Patients Receiving Androgen-Deprivation Therapy
Published in Clinical cancer research (15-02-2011)“…Recent evidence indicates that small noncoding RNA molecules, known as microRNAs (miRNAs), are involved in cancer initiation and progression. We hypothesized…”
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9
Genetic variants in the Hippo pathway predict biochemical recurrence after radical prostatectomy for localized prostate cancer
Published in Scientific reports (24-02-2015)“…While localized prostate cancer is potentially curative, many patients still show biochemical recurrence (BCR) after curative treatments such as radical…”
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10
Synthesis and antiproliferative evaluation of oxime, methyloxime, and amide‐containing quinazolinones
Published in Journal of the Chinese Chemical Society (Taipei) (01-09-2018)“…Certain oxime, methyloxime, and amide‐containing quinazolinone derivatives were synthesized and evaluated in vitro for their antiproliferative activities…”
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11
Synthesis and evaluation of in vitro bioactivity for polysubstituted N-arylpyrazole derivatives
Published in Arabian journal of chemistry (01-12-2019)“…[Display omitted] New polysubstituted N-arylpyrazole derivatives were synthesized from N1-arylsydnone with acetylene and boronic acid, including 2-thiophenyl,…”
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12
WTC‐01, a novel synthetic oxime‐flavone compound, destabilizes microtubules in human nasopharyngeal carcinoma cells in vitro and in vivo
Published in British journal of pharmacology (01-10-2015)“…Background and Purpose Dynamic polymerization of microtubules is essential for cancer cell growth and metastasis, and microtubule‐disrupting agents have become…”
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13
Suppression on metastasis by rhubarb through modulation on MMP-2 and uPA in human A549 lung adenocarcinoma: An ex vivo approach
Published in Journal of ethnopharmacology (27-01-2011)“…The aim of this study is to determine and identify the possible molecular mechanisms of anti-cancer effect of rhubarb under the physiologically achievable…”
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14
Synthesis and evaluation of isatin derivatives as effective SARS coronavirus 3CL protease inhibitors
Published in Bioorganic & medicinal chemistry letters (15-06-2005)“…N-Substituted isatin derivatives have been prepared and their inhibition activities against SARS viral protease were evaluated. N-Substituted isatin…”
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15
Synthesis and Antiproliferative Evaluation of Amide-Containing Anthraquinone, Xanthone, and Carbazole
Published in Chemical & pharmaceutical bulletin (01-01-2014)“…Certain amide-containing anthraquinone, xanthone, and carbazole derivatives have been synthesized and evaluated in vitro for their antiproliferative activities…”
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16
The constituents of Michelia compressa var. formosana and their bioactivities
Published in International journal of molecular sciences (17-06-2014)“…Phytochemical investigation of the heartwood of Michelia compressa afforded forty-four compounds, which were identified by comparison of experimental and…”
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17
Chemical constituents from Andrographis echioides and their anti-inflammatory activity
Published in International journal of molecular sciences (27-12-2012)“…Phytochemical investigation of the whole plants of Andrographis echioides afforded two new 2'-oxygenated flavonoids (1) and (2), two new phenyl glycosides (3)…”
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18
The Inhibitory Mechanisms Study of 5,6,4'-Trihydroxy-7,3'-Dimethoxyflavone against the LPS-Induced Macrophage Inflammatory Responses through the Antioxidant Ability
Published in Molecules (Basel, Switzerland) (22-01-2016)“…The whole plant of Anisomeles ovata has been widely used in Taiwan for treating inflammation-related skin and liver diseases, however, the detailed…”
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Synthesis and antiproliferative evaluation of 3,5-disubstituted 1,2,4-triazoles containing flurophenyl and trifluoromethanephenyl moieties
Published in Bioorganic & medicinal chemistry letters (15-09-2011)“…An efficient 1,3-dipolar cycloaddition method was performed for the synthesis of a series of monofluoro- and trifluoromethane-3,5-disubstituted…”
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20
Metabolism and Pharmacokinetics of San-Huang-Xie-Xin-Tang, a Polyphenol-Rich Chinese Medicine Formula, in Rats and Ex-Vivo Antioxidant Activity
Published in Evidence-based complementary and alternative medicine (01-01-2011)“…San-Huang-Xie-Xin-Tang (SHXXT), a widely used Chinese herbal formula, consists of rhizomes of Rheum officinale, roots of Scutellaria baicalensis and rhizomes…”
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