Search Results - "Juan, Santibañez F."

TGF-β/TGF-β receptor system and its role in physiological and pathological conditions by Santibañez, Juan F, Quintanilla, Miguel, Bernabeu, Carmelo

“…The TGF-β (transforming growth factor-β) system signals via protein kinase receptors and Smad mediators to regulate a plethora of biological processes,…”
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Oxidative Stress in Disease and Aging: Mechanisms and Therapies 2016 by Cabello-Verrugio, Claudio, Simon, Felipe, Trollet, Capucine, Santibañez, Juan F.

“…Oxidative stress (OS) is an imbalance between the formation of reactive oxygen species (ROS) and antioxidant defense mechanisms. This phenomenon increases with…”
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Interleukin-17 and Its Implication in the Regulation of Differentiation and Function of Hematopoietic and Mesenchymal Stem Cells by Bugarski, Diana, Santibanez, Juan F., Krstić, Aleksandra, Mojsilović, Slavko

“…Adult stem cells have a great potential applicability in regenerative medicine and cell-based therapies. However, there are still many unresolved issues…”
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Interleukin 17 inhibits myogenic and promotes osteogenic differentiation of C2C12 myoblasts by activating ERK1,2 by Kocić, Jelena, Santibañez, Juan F., Krstić, Aleksandra, Mojsilović, Slavko, Đorđević, Ivana Okić, Trivanović, Drenka, Ilić, Vesna, Bugarski, Diana

“…The present study evaluated the role of interleukin (IL) 17 in multilineage commitment of C2C12 myoblastic cells and investigated associated signaling…”
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The inhibition of periodontal ligament stem cells osteogenic differentiation by IL-17 is mediated via MAPKs by Đorđević, Ivana Okić, Kukolj, Tamara, Krstić, Jelena, Trivanović, Drenka, Obradović, Hristina, Santibañez, Juan F., Mojsilović, Slavko, Ilić, Vesna, Bugarski, Diana, Jauković, Aleksandra

“…Periodontal disease (PD), a degenerative bacterially induced disease of periodontium, can lead to bone resorption and teeth loss. Development of PD includes a…”
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Interleukin-17 modulates myoblast cell migration by inhibiting urokinase type plasminogen activator expression through p38 mitogen-activated protein kinase by Kocić, Jelena, Santibañez, Juan F., Krstić, Aleksandra, Mojsilović, Slavko, Ilić, Vesna, Bugarski, Diana

“…► IL-17 inhibits urokinase type plasminogen activator (uPA) expression in C2C12 myoblasts. ► The inhibition of uPA expression was concomitant with IL-17…”
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Urokinase type plasminogen activator mediates Interleukin-17-induced peripheral blood mesenchymal stem cell motility and transendothelial migration by Krstić, Jelena, Obradović, Hristina, Jauković, Aleksandra, Okić-Đorđević, Ivana, Trivanović, Drenka, Kukolj, Tamara, Mojsilović, Slavko, Ilić, Vesna, Santibañez, Juan F., Bugarski, Diana

“…Mesenchymal stem cells (MSCs) have the potential to migrate toward damaged tissues increasing tissue regeneration. Interleukin-17 (IL-17) is a proinflammatory…”
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Distinctive Archaeal Composition of an Artisanal Crystallizer Pond and Functional Insights Into Salt-Saturated Hypersaline Environment Adaptation by Plominsky, Alvaro M, Henríquez-Castillo, Carlos, Delherbe, Nathalie, Podell, Sheila, Ramirez-Flandes, Salvador, Ugalde, Juan A, Santibañez, Juan F, van den Engh, Ger, Hanselmann, Kurt, Ulloa, Osvaldo, De la Iglesia, Rodrigo, Allen, Eric E, Trefault, Nicole

“…Hypersaline environments represent some of the most challenging settings for life on Earth. Extremely halophilic microorganisms have been selected to colonize…”
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Transforming Growth Factor-Beta and Matrix Metalloproteinases: Functional Interactions in Tumor Stroma-Infiltrating Myeloid Cells by Kocić, Jelena, Santibanez, Juan F.

“…Transforming growth factor-beta (TGF-β) is a pleiotropic factor with several different roles in health and disease. In tumorigenesis, it may act as a…”
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In vitro effects of IL-17 on angiogenic properties of endothelial cells in relation to oxygen levels by Krstić, Jelena, Jauković, Aleksandra, Mojsilović, Slavko, Đorđević, Ivana Okić, Trivanović, Drenka, Ilić, Vesna, Santibañez, Juan F., Bugarski, Diana

“…The aim of this study has been to elucidate how different oxygen levels impact the effects of Interleukin‐17 (IL‐17) on angiogenic properties of endothelial…”
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JNK mediates TGF-β1-induced epithelial mesenchymal transdifferentiation of mouse transformed keratinocytes by Santibañez, Juan F.

“…In this study we analyzed the role of the c-Jun N-terminal kinases (JNK) pathway in the TGF-β1 stimulation of urokinase-type plasminogen activator (uPA),…”
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Transforming Growth Factor-Beta and Oxidative Stress Interplay: Implications in Tumorigenesis and Cancer Progression by Santibanez, Juan F., Mojsilović, Slavko, Trivanović, Drenka, Kocić, Jelena

“…Transforming growth factor-beta (TGF-β) and oxidative stress/Reactive Oxygen Species (ROS) both have pivotal roles in health and disease. In this review we are…”
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ROS-NFκΒ mediates TGF-β1-induced expression of urokinase-type plasminogen activator, matrix metalloproteinase-9 and cell invasion by Tobar, Nicolas, Villar, Victor, Santibanez, Juan F

“…TGF-β1 has been postulated as a pro-oncogenic factor in the late step of the tumoral progression. In transformed cells, TGF-β1 enhances the capacity to degrade…”
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Ha-Ras sensitizes transformed mouse skin cells to Anisomycin-induced apoptosis by Santibañez, Juan F., Hurtado, Claudia

“…Efforts have been made to develop a chemoprevention that selectively triggers apoptosis in malignant cancer cells. Here, we demonstrated that a mutated Ha-Ras…”
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Epidermal growth factor stimulates urokinase-type plasminogen activator expression in human gingival fibroblasts. Possible modulation by genistein and curcumin by Smith, Patricio C., Santibañez, Juan F., Morales, Juan P., Martinez, Jorge

“…Background:  Regulation of the extracellular matrix turnover is a crucial process in wound healing and the progress of periodontal disease. It has been…”
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Urokinase Type Plasminogen Activator and the Molecular Mechanisms of its Regulation in Cancer by Santibanez, Juan F

“…Urokinase type plasminogen activator (uPA) is a 53-kDa serine protease initially synthesized as a catalytically inactive single chain polypeptide. Inactive-uPA…”
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Targeting Histone Deacetylases: Opportunities for Cancer Treatment and Chemoprevention by Ruzic, Dusan, Djoković, Nemanja, Srdić-Rajić, Tatjana, Echeverria, Cesar, Nikolic, Katarina, Santibanez, Juan F

“…The dysregulation of gene expression is a critical event involved in all steps of tumorigenesis. Aberrant histone and non-histone acetylation modifications of…”
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Inhibition of proinflammatory signaling impairs fibrosis of bone marrow mesenchymal stromal cells in myeloproliferative neoplasms by Vukotić, Milica, Kapor, Sunčica, Dragojević, Teodora, Đikić, Dragoslava, Mitrović Ajtić, Olivera, Diklić, Miloš, Subotički, Tijana, Živković, Emilija, Beleslin Čokić, Bojana, Vojvodić, Aleksandar, Santibáñez, Juan F., Gotić, Mirjana, Čokić, Vladan P.

“…Although bone marrow-derived mesenchymal stromal cells (BM-MSCs) have been identified as a major cellular source of fibrosis, the exact molecular mechanism and…”
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Author Correction: Iscador Qu inhibits doxorubicin-induced senescence of MCF7 cells by Srdic-Rajic, Tatjana, Santibañez, Juan F., Kanjer, Ksenija, Tisma-Miletic, Nevena, Cavic, Milena, Galun, Daniel, Jevric, Marko, Kardum, Nevena, Konic-Ristic, Aleksandra, Zoranovic, Tamara

“…A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper…”
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Current and Future Cancer Chemoprevention Strategies by Santibanez, Juan F, Villar, Victor H, Echeverria, Cesar

“…Cancer is a leading cause of death worldwide, accounting for nearly 10 million deaths in 2020 and ranking as the second-leading cause of death in economically…”
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