Search Results - "Ju, S T"

Novel animal models for Sjögren's syndrome: Expression and transfer of salivary gland dysfunction from regulatory T cell-deficient mice by Sharma, R., Zheng, L., Guo, X., Fu, S.M., Ju, S.-T., Jarjour, W.N.

“…IL-2 knockout (KO), IL-2Rα KO and scurfy mice lack the CD4 +CD25 + regulatory T (Treg) cells and develop severe inflammation in multiple organs, although…”
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Fas Ligand Engagement of Resident Peritoneal Macrophages In Vivo Induces Apoptosis and the Production of Neutrophil Chemotactic Factors by Hohlbaum, Andreas M, Gregory, Meredith S, Ju, Shyr-Te, Marshak-Rothstein, Ann

“…Fas ligand (FasL) is a potent proapoptotic type-II transmembrane protein that can cause cell death in Fas+ target populations. Despite the presumed "silent"…”
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CD95 (Fas) Ligand-Expressing Vesicles Display Antibody-Mediated, FcR-Dependent Enhancement of Cytotoxicity by Jodo, Satoshi, Hohlbaum, Andreas M, Xiao, Sheng, Chan, Derek, Strehlow, David, Sherr, David H, Marshak-Rothstein, Ann, Ju, Shyr-Te

“…Bioactive Fas ligand (FasL)-expressing vesicles were generated (vesicle preparation, VP) from two cell lines overexpressing FasL. The effect of NOK-1 anti-FasL…”
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Participation of Target Fas Protein in Apoptosis Pathway Induced by CD4+Th1 and CD8+Cytotoxic T Cells by Ju, Shyr-Te, Cui, Haili, Panka, David J., Ettinger, Rachel, Marshak-Rothstein, Ann

“…The results presented here provide evidence that the presence of Fas protein in target cells is essential to permit cytotoxicity (resulting in apoptosis)…”
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FasL promoter activation by IL‐2 through SP1 and NFAT but not Egr‐2 and Egr‐3 by Xiao, Sheng, Matsui, Ken, Fine, Alan, Zhu, Bangmin, Marshak‐Rothstein, Ann, Widom, Russel L., Ju, Shyr‐Te

“…Recently activated peripheral T cells treated with IL‐2 for 4 days expressed Fas ligand (FasL)‐mediated cytotoxicity. These IL‐2‐treated T cells had high…”
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Fluoranthene-Induced Apoptosis in Murine T Cell Hybridomas Is Independent of the Aromatic Hydrocarbon Receptor by Yamaguchi, Koichi, Near, Richard, Shneider, Alexander, Cui, Haili, Ju, Shyr-Te, Sherr, David H.

“…Recent studies suggest that environmental chemicals such as polycyclic aromatic hydrocarbons (PAH) compromise the immune system in part through the induction…”
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Bioactivities of Fas Ligand-Expressing Retroviral Particles by Jodo, Satoshi, Strehlow, David, Ju, Shyr-Te

“…Culture supernatants from retroviral packaging cells carrying the human Fas ligand (FasL) gene killed both human (Jurkat) and mouse (LB27.4) targets within 5 h…”
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Expression of two distinct cytolytic mechanisms among murine CD4 subsets by BS.-T, JU, RUDDLE, N. H, STRACK, P, DORF, M. E, DEKRUYFF, R. H

“…A TNF (TNF-alpha and TNF-beta)-sensitive target, L929, and two TNF-resistant targets, P815 and LK were used to compare the cytolytic activity among subsets of…”
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Biological factors that affect CD95 ligand-mediated inflammation by Seino, K, Ogino, T, Ju, S.-T, Hamada, H, Yagita, H, Okumura, K, Fukao, K

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Identification of two NF-kappa B sites in mouse CD95 ligand (Fas ligand) promoter: functional analysis in T cell hybridoma by Matsui, K, Fine, A, Zhu, B, Marshak-Rothstein, A, Ju, S T

“…Fas ligand (FasL) gene expression is critically involved in peripheral T cell tolerance and lymphocyte homeostasis. Previous studies have suggested that…”
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The CD3‐gamma and CD3‐delta subunits of the T cell antigen receptor can be expressed within distinct functional TCR/CD3 complexes by Alarcón, B., Ley, S. C., Sánchez‐Madrid, F., Blumberg, R. S., Ju, S. T., Fresno, M., Terhorst, C.

“…The T cell receptor for antigen (TCR) consists of two glycoproteins containing variable regions (TCR‐alpha/beta or TCR‐gamma/delta) which are expressed on the…”
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Apoptosis-inducing membrane vesicles. A novel agent with unique properties by Jodo, S, Xiao, S, Hohlbaum, A, Strehlow, D, Marshak-Rothstein, A, Ju, S T

“…The CD95 ligand (FasL) transmembrane protein is found on activated T cells and cells outside the immune system. A well-known turnover process of membrane FasL…”
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Induction of antigen-specific antibody responses in primed and unprimed B cells. Functional heterogeneity among Th1 and Th2 T cell clones by DeKruyff, RH, Ju, ST, Hunt, AJ, Mosmann, TR, Umetsu, DT

“…CD4+ T cells have been recently divided into two subsets. The functions of these subsets are thought to be distinct: one subset (Th1) is responsible for…”
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A novel cytotoxicity of CD4+ Th1 clones on heat-shocked tumor targets. I. Implications for internal disintegration model for target death and hyperthermia treatment of cancers by Ozdemirli, M, Akdeniz, H, el-Khatib, M, Ju, ST

“…A novel cytotoxicity, which is normally hidden but unveiled upon interacting with heat-shocked tumor target, has been identified in CD4+ Th1 cells. When…”
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Fas(CD95)/FasL interactions required for programmed cell death after T-cell activation by Ju, Shyr-Te, Panka, David J, Cui, Haili, Ettinger, Rachel, EI-Khatib, Maan, Sherr, David H, Stanger, Ben Z, Marshak-Rothstein, Ann

“…Receptor crosslinking of T-cell hybridomas induces cell activation followed by apoptosis. This activation-induced cell death requires de novo synthesis of RNA…”
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Amyloid enhancing factor-loaded macrophages in amyloid fibril formation by Shirahama, T, Miura, K, Ju, S T, Kisilevsky, R, Gruys, E, Cohen, A S

“…Amyloid enhancing factor (AEF) is believed to be a key agent that triggers the second (deposition) phase of amyloidogenesis. However, the target cells of AEF…”
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Cytokines and adhesion molecules contribute to the ability of myelin proteolipid protein-specific T cell clones to mediate experimental allergic encephalomyelitis by Kuchroo, VK, Martin, CA, Greer, JM, Ju, ST, Sobel, RA, Dorf, ME

“…We have derived a panel of CD4+, TCR-alpha/beta + T cell clones from SJL (H-2s) mice specific for an encephalitogenic determinant of myelin proteolipid protein…”
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Activation requirements of cloned inducer T cells. III. Need for two stimulator cells in the response of a cloned line to Mls determinants by DeKruyff, RH, Ju, ST, Laning, J, Cantor, H, Dorf, ME

“…To gain insight into the nature of Mls determinants, we examined the stimulator cells responsible for the activation of inducer T cell clones by Mls…”
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Idiotype-specific helper cells (BH) express immunoglobulin markers and employ T cell function-associated molecules by Sherr, DH, Ju, ST

“…An Lyt-1+ population, distinct from T cell subsets, that helps expression of B cell responses to the 4-hydroxy-3-nitrophenyl acetyl (NP) hapten was…”
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Combining Fas mutation with interleukin-2 deficiency prevents Colitis and Lupus: implicating interleukin-2 for auto-reactive T cell expansion and Fas ligand for colon epithelial cell death by Xiao, Sheng, Sung, Sun-Sang J, Fu, Shu Man, Ju, Shyr-Te

“…Both the lpr gene defect and interleukin 2-targeted mutation (IL-2 KO) in mice are lethal. Interestingly, mice bearing both mutations live significantly longer…”
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