Search Results - "Ju, Gaoda"
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TSPAN8 promotes cancer cell stemness via activation of sonic Hedgehog signaling
Published in Nature communications (28-06-2019)“…Cancer stem cells (CSCs) represent a major source of treatment resistance and tumor progression. However, regulation of CSCs stemness is not entirely…”
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CRISPR screens uncover protective effect of PSTK as a regulator of chemotherapy-induced ferroptosis in hepatocellular carcinoma
Published in Molecular cancer (04-01-2022)“…Hepatocellular carcinoma (HCC) is among the most common forms of cancer and is associated with poor patient outcomes. The emergence of therapeutic resistance…”
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AEBP1 promotes papillary thyroid cancer progression by activating BMP4 signaling
Published in Neoplasia (New York, N.Y.) (01-03-2024)“…•AEBP1 promotes growth, and migration of PTC cells in vitro and in vivo.•AEBP1 induces epithelial-mesenchymal transition in PTC progression.•BMP4 mediates the…”
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ARID1A deficiency promotes progression and potentiates therapeutic antitumour immunity in hepatitis B virus-related hepatocellular carcinoma
Published in BMC gastroenterology (02-01-2024)“…Exploring predictive biomarkers and therapeutic strategies of ICBs has become an urgent need in clinical practice. Increasing evidence has shown that ARID1A…”
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DUSP12 regulates the tumorigenesis and prognosis of hepatocellular carcinoma
Published in PeerJ (San Francisco, CA) (03-08-2021)“…Background Dual specificity protein phosphatase ( DUSP)12 is an atypical member of the protein tyrosine phosphatase family, which are overexpressed in multiple…”
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In vitro CRISPR screening uncovers CRTC3 as a regulator of IFN-γ-induced ferroptosis of hepatocellular carcinoma
Published in Cell death discovery (04-09-2023)“…Interferon-gamma (IFN-γ) exerts anti-tumor effects by inducing ferroptosis. Based on CRISPR/Cas9 knockout screening targeting genome-wide protein encoding…”
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Corrigendum: Identification of DYNLT1 associated with proliferation, relapse, and metastasis in breast cancer
Published in Frontiers in medicine (05-02-2024)“…[This corrects the article DOI: 10.3389/fmed.2023.1167676.]…”
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Correction: In vitro CRISPR screening uncovers CRTC3 as a regulator of IFN-γ-induced ferroptosis of hepatocellular carcinoma
Published in Cell death discovery (18-12-2023)Get full text
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Identification of DYNLT1 associated with proliferation, relapse, and metastasis in breast cancer
Published in Frontiers in medicine (04-04-2023)“…Breast cancer (BC) is the most common malignant disease worldwide. Although the survival rate is improved in recent years, the prognosis is still bleak once…”
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DTYMK promote hepatocellular carcinoma proliferation by regulating cell cycle
Published in Cell cycle (Georgetown, Tex.) (02-09-2021)“…Overexpression of DTYMK is related with tumorigenesis and progression in several human tumors. However, the role of upregulated DTYMK in hepatocellular…”
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A nomogram based on a three pyroptosis gene model and clinical parameters for predicting prognosis of hepatocellular carcinoma
Published in Gene (20-04-2022)“…[Display omitted] •We developed and validated a prognostic model based on 3 pyroptosis genes for predicting survival of patients with HCC;•High expression of…”
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Characterizing Genetic Alterations Related to Radioiodine Avidity in Metastatic Thyroid Cancer
Published in The journal of clinical endocrinology and metabolism (19-04-2024)“…Patients with differentiated thyroid cancer (DTC) with distant metastasis (DM) are usually not recognized as radioactive iodine (RAI)-refractory DTC in a…”
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Fusion Oncogenes in Patients With Locally Advanced or Distant Metastatic Differentiated Thyroid Cancer
Published in The journal of clinical endocrinology and metabolism (18-01-2024)“…Abstract Context Fusion oncogenes are involved in the underlying pathology of advanced differentiated thyroid cancer (DTC), and even the cause of radioactive…”
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High expression of transmembrane P24 trafficking protein 9 predicts poor prognosis in breast carcinoma
Published in Bioengineered (01-01-2021)“…Over the years, molecular subtypes based on estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor-2 (HER-2) status…”
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GLUT1/3/4 as novel biomarkers for the prognosis of human breast cancer
Published in Translational cancer research (01-04-2020)“…Anomalous expression of glucose transporters (GLUTs) has been observed in a variety of tumor tissues. Although GLUT factors have been shown to have prognostic…”
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Abstract 2848: TSPAN8-EPS8L3 signaling play a role in EGF-dependent pancreatic cancer cell invasion and migration
Published in Cancer research (Chicago, Ill.) (01-07-2019)“…Abstract The mechanism and function of TSPAN8 on the invasion and metastasis of cancer cells is poorly understood. In present study, we demonstrated that…”
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Identification and validation of the cellular senescence-related molecular subtypes of triple negative breast cancer via integrating bulk and single-cell RNA sequencing data
Published in American journal of cancer research (01-01-2023)“…Patients with triple-negative breast cancer (TNBC) reportedly benefit from immune checkpoint blockade (ICB) therapy. However, the subtype-specific…”
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Targeting the TCA cycle through cuproptosis confers synthetic lethality on ARID1A-deficient hepatocellular carcinoma
Published in Cell reports. Medicine (21-11-2023)“…ARID1A is among the most commonly mutated tumor suppressor genes in hepatocellular carcinoma (HCC). In this study, we conduct a CRISPR-Cas9 synthetic lethality…”
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Identification and Validation of a Prognostic Signature Based on Methylation Profiles and Methylation-Driven Gene DAB2 as a Prognostic Biomarker in Differentiated Thyroid Carcinoma
Published in Disease markers (2022)“…Recurrence is the major death cause of differentiated thyroid carcinoma (DTC), and a better understanding of recurrence risk at early stage may lead to make…”
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