Search Results - "Joynson, Greg"

Early doors (Edo) mutant mouse reveals the importance of period 2 (PER2) PAS domain structure for circadian pacemaking by Militi, Stefania, Maywood, Elizabeth S., Sandate, Colby R., Chesham, Johanna E., Barnard, Alun R., Parsons, Michael J., Vibert, Jennifer L., Joynson, Greg M., Partch, Carrie L., Hastings, Michael H., Nolan, Patrick M.

“…The suprachiasmatic nucleus (SCN) defines 24 h of time via a transcriptional/posttranslational feedback loop in which transactivation of Per (period) and Cry…”
Get full text

Zfhx3 modulates retinal sensitivity and circadian responses to light by Hughes, Steven, Edwards, Jessica K., Wilcox, Ashleigh G., Pothecary, Carina A., Barnard, Alun R., Joynson, Russell, Joynson, Greg, Hankins, Mark W., Peirson, Stuart N., Banks, Gareth, Nolan, Patrick M.

“…Mutations in transcription factors often exhibit pleiotropic effects related to their complex expression patterns and multiple regulatory targets. One such…”
Get full text

Distinct and separable roles for endogenous CRY1 and CRY2 within the circadian molecular clockwork of the suprachiasmatic nucleus, as revealed by the Fbxl3(Afh) mutation by Anand, Sneha N, Maywood, Elizabeth S, Chesham, Johanna E, Joynson, Greg, Banks, Gareth T, Hastings, Michael H, Nolan, Patrick M

“…The circadian clock of the suprachiasmatic nucleus (SCN) drives daily rhythms of behavior. Cryptochromes (CRYs) are powerful transcriptional repressors within…”
Get full text

The Regulatory Factor ZFHX3 Modifies Circadian Function in SCN via an AT Motif-Driven Axis by Parsons, Michael J., Brancaccio, Marco, Sethi, Siddharth, Maywood, Elizabeth S., Satija, Rahul, Edwards, Jessica K., Jagannath, Aarti, Couch, Yvonne, Finelli, Mattéa J., Smyllie, Nicola J., Esapa, Christopher, Butler, Rachel, Barnard, Alun R., Chesham, Johanna E., Saito, Shoko, Joynson, Greg, Wells, Sara, Foster, Russell G., Oliver, Peter L., Simon, Michelle M., Mallon, Ann-Marie, Hastings, Michael H., Nolan, Patrick M.

“…We identified a dominant missense mutation in the SCN transcription factor Zfhx3, termed short circuit (Zfhx3Sci), which accelerates circadian locomotor…”
Get full text

Distinct and Separable Roles for Endogenous CRY1 and CRY2 within the Circadian Molecular Clockwork of the Suprachiasmatic Nucleus, as Revealed by the Fbxl3 Afh Mutation by Anand, Sneha N., Maywood, Elizabeth S., Chesham, Johanna E., Joynson, Greg, Banks, Gareth T., Hastings, Michael H., Nolan, Patrick M.

“…The circadian clock of the suprachiasmatic nucleus (SCN) drives daily rhythms of behavior. Cryptochromes (CRYs) are powerful transcriptional repressors within…”
Get full text

Distinct and Separable Roles for Endogenous CRY1 and CRY2 within the Circadian Molecular Clockwork of the Suprachiasmatic Nucleus, as Revealed by the Fbxl3Afh Mutation by Anand, Sneha N, Maywood, Elizabeth S, Chesham, Johanna E, Joynson, Greg, Banks, Gareth T, Hastings, Michael H, Nolan, Patrick M

“…The circadian clock of the suprachiasmatic nucleus (SCN) drives daily rhythms of behavior. Cryptochromes (CRYs) are powerful transcriptional repressors within…”
Get full text