Search Results - "Joy, Shona"

NRF2 Orchestrates the Metabolic Shift during Induced Pluripotent Stem Cell Reprogramming by Hawkins, Kate E., Joy, Shona, Delhove, Juliette M.K.M., Kotiadis, Vassilios N., Fernandez, Emilio, Fitzpatrick, Lorna M., Whiteford, James R., King, Peter J., Bolanos, Juan P., Duchen, Michael R., Waddington, Simon N., McKay, Tristan R.

“…The potential of induced pluripotent stem cells (iPSCs) in disease modeling and regenerative medicine is vast, but current methodologies remain inefficient…”
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Aberrant Development Corrected in Adult-Onset Huntington's Disease iPSC-Derived Neuronal Cultures via WNT Signaling Modulation by Smith-Geater, Charlene, Hernandez, Sarah J., Lim, Ryan G., Adam, Miriam, Wu, Jie, Stocksdale, Jennifer T., Wassie, Brook T., Gold, Maxwell Philip, Wang, Keona Q., Miramontes, Ricardo, Kopan, Lexi, Orellana, Iliana, Joy, Shona, Kemp, Paul J., Allen, Nicholas D., Fraenkel, Ernest, Thompson, Leslie M.

“…Aberrant neuronal development and the persistence of mitotic cellular populations have been implicated in a multitude of neurological disorders, including…”
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Cell signalling pathways underlying induced pluripotent stem cell reprogramming by Hawkins, Kate, Joy, Shona, McKay, Tristan

“…Induced pluripotent stem(i PS) cells, somatic cells reprogrammed to the pluripotent state by forced expression of defined factors, represent a uniquely…”
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Forced cell cycle exit and modulation of GABAA, CREB, and GSK3β signaling promote functional maturation of induced pluripotent stem cell-derived neurons by Telezhkin, Vsevolod, Schnell, Christian, Yarova, Polina, Yung, Sun, Cope, Emma, Hughes, Alis, Thompson, Belinda A, Sanders, Philip, Geater, Charlene, Hancock, Jane M, Joy, Shona, Badder, Luned, Connor-Robson, Natalie, Comella, Andrea, Straccia, Marco, Bombau, Georgina, Brown, Jon T, Canals, Josep M, Randall, Andrew D, Allen, Nicholas D, Kemp, Paul J

“…Although numerous protocols have been developed for differentiation of neurons from a variety of pluripotent stem cells, most have concentrated on being able…”
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Human tau mutations in cerebral organoids induce a progressive dyshomeostasis of cholesterol by Glasauer, Stella M.K., Goderie, Susan K., Rauch, Jennifer N., Guzman, Elmer, Audouard, Morgane, Bertucci, Taylor, Joy, Shona, Rommelfanger, Emma, Luna, Gabriel, Keane-Rivera, Erica, Lotz, Steven, Borden, Susan, Armando, Aaron M., Quehenberger, Oswald, Temple, Sally, Kosik, Kenneth S.

“…Mutations in the MAPT gene that encodes tau lead to frontotemporal dementia (FTD) with pathology evident in both cerebral neurons and glia. Human cerebral…”
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Directed differentiation of human pluripotent stem cells to telencephalic lateral ganglionic eminence progenitors using small molecules by Joy, Shona

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