Search Results - "Jowhar, Ziad"
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A ubiquitous GC content signature underlies multimodal mRNA regulation by DDX3X
Published in Molecular systems biology (04-03-2024)“…The road from transcription to protein synthesis is paved with many obstacles, allowing for several modes of post-transcriptional regulation of gene…”
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Student, Staff and Faculty Experience with a Medical School Racial and Sociopolitical Trauma Protocol: A Mixed Methods Study
Published in Teaching and learning in medicine (07-06-2024)“… Medical students experience racial and sociopolitical trauma that disrupts their learning and wellbeing. University of California, San Francisco (UCSF)…”
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3
Cell cycle-dependent association of polo kinase Cdc5 with CENP-A contributes to faithful chromosome segregation in budding yeast
Published in Molecular biology of the cell (01-04-2019)“…Evolutionarily conserved polo-like kinase, Cdc5 (Plk1 in humans), associates with kinetochores during mitosis; however, the role of cell cycle-dependent…”
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4
Institutionalizing Rest in Response to Racial and Sociopolitical Trauma
Published in Academic medicine (01-06-2022)Get full text
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Institutionalizing Rest in Response to Racial and Sociopolitical Trauma
Published in Academic medicine (07-09-2021)Get full text
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6
A Ubiquitous GC Content Signature Underlies Multimodal mRNA Regulation by DDX3X
Published 01-01-2024“…DDX3X encodes for a DEAD-box RNA helicase that promotes the translation of mRNAs that contain long, highly structured 5′ UTRs. DDX3X interacts with translation…”
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Dissertation -
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Genome-wide quantification of RNA flow across subcellular compartments reveals determinants of the mammalian transcript life cycle
Published in Molecular cell (25-07-2024)“…Dissecting the regulatory mechanisms controlling mammalian transcripts from production to degradation requires quantitative measurements of mRNA flow across…”
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Journal Article -
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G3BP isoforms differentially affect stress granule assembly and gene expression during cellular stress
Published in Molecular biology of the cell (01-11-2024)“…Stress granules (SGs) are macromolecular assemblies that form under cellular stress. Formation of these membraneless organelles is driven by the condensation…”
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Journal Article -
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Effects of human sex chromosome dosage on spatial chromosome organization
Published in Molecular biology of the cell (01-10-2018)“…Sex chromosome aneuploidies (SCAs) are common genetic syndromes characterized by the presence of an aberrant number of X and Y chromosomes due to meiotic…”
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HiCTMap: Detection and analysis of chromosome territory structure and position by high-throughput imaging
Published in Methods (San Diego, Calif.) (01-06-2018)“…•High-throughput imaging method for visualization of chromosome territories.•Quantitation of structural and spatial features of chromosomes in 2D and…”
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IGHMBP2 deletion suppresses translation and activates the integrated stress response
Published in Life science alliance (01-08-2024)“…IGHMBP2 is a nonessential, superfamily 1 DNA/RNA helicase that is mutated in patients with rare neuromuscular diseases SMARD1 and CMT2S. IGHMBP2 is implicated…”
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12
G3BP isoforms differentially affect stress granule assembly and gene expression during cellular stress
Published in Molecular biology of the cell (02-10-2024)“…Stress granules (SGs) are macromolecular assemblies that form under cellular stress. Formation of these membrane-less organelles is driven by the condensation…”
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Journal Article -
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Polo kinase Cdc5 associates with centromeres to facilitate the removal of centromeric cohesin during mitosis
Published in Molecular biology of the cell (15-07-2016)“…Sister chromatid cohesion is essential for tension-sensing mechanisms that monitor bipolar attachment of replicated chromatids in metaphase. Cohesion is…”
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14
Rapid deployment of SARS-CoV-2 testing: The CLIAHUB
Published in PLoS pathogens (28-10-2020)“…About the Authors: Emily D. Crawford Affiliations Chan Zuckerberg Biohub, San Francisco, California, United States of America, University of California San…”
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Journal Article