Search Results - "Jouzeau, J Y"
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Review article: moving towards common therapeutic goals in Crohn's disease and rheumatoid arthritis
Published in Alimentary Pharmacology & Therapeutics (Suppl) (01-04-2017)“…Summary Background Crohn's disease (CD) and rheumatoid arthritis are chronic, progressive and disabling conditions that frequently lead to structural tissue…”
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Association between adiponectin and cartilage degradation in human osteoarthritis
Published in Osteoarthritis and cartilage (01-03-2014)“…Summary Objective Conflicting findings raise questions about the role of adiponectin in osteoarthritis (OA). The current study aimed to investigate in OA…”
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Elevated hepatocyte growth factor levels in osteoarthritis osteoblasts contribute to their altered response to bone morphogenetic protein-2 and reduced mineralization capacity
Published in Bone (New York, N.Y.) (01-06-2015)“…Abstract Purpose Clinical and in vitro studies suggest that subchondral bone sclerosis due to abnormal osteoblasts is involved in the progression of…”
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Fibroblast Growth Factor 23 drives MMP13 expression in human osteoarthritic chondrocytes in a klotho-independent manner
Published in Osteoarthritis and cartilage (01-11-2016)“…Summary Objective Fibroblast Growth Factor 23 (FGF23) may represent an attractive candidate that could participate to the osteoarthritic (OA)-induced phenotype…”
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Identification of TGFβ signatures in six murine models mimicking different osteoarthritis clinical phenotypes
Published in Osteoarthritis and cartilage (01-10-2020)“…TGFβ is a key player in cartilage homeostasis and OA pathology. However, few data are available on the role of TGFβ signalling in the different OA phenotypes…”
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Site specific changes in gene expression and cartilage metabolism during early experimental osteoarthritis
Published in Osteoarthritis and cartilage (01-04-2004)“…Objectives: To characterize the molecular events underlying cartilage injury in the early phase of mono-iodoacetate-induced osteoarthritis (OA) in rats…”
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Identification of new microRNAs targeting genes regulating the Pi/PPi balance in chondrocytes
Published in Bio-medical materials and engineering (2014)“…Osteoarthritis (OA) is a whole-joint disease characterized by cartilage degradation and mineralization associated with chondrocyte phenotype changes,…”
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Cytocompatibility of Ti-6Al-4V and Ti-5Al-2.5Fe alloys according to three surface treatments, using human fibroblasts and osteoblasts
Published in Biomaterials (1996)“…Titanium alloys are well known for their superior mechanical properties as well as for their good biocompatibility, making them desirable as surgical implant…”
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Cyclo-oxygenase isoenzymes : How recent findings affect thinking about nonsteroidal anti-inflammatory drugs
Published in Drugs (New York, N.Y.) (01-04-1997)“…The discovery of at least 2 cyclo-oxygenase (COX) isoenzymes, referred to as COX-1 and COX-2, has updated our knowledge of nonsteroidal anti-inflammatory drugs…”
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Plasma surface treatment and PACVD on Ti alloys for surgical implants
Published in Surface & coatings technology (01-10-1995)“…To improve the poor surface hardness and wear resistance of titanium alloys used for surgical implants undergoing wear TiA16V4 and TiA15Fe2.5 have been plasma…”
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Evidence for species differences in the regulation of MMPs by all-trans retinoic acid in cytokine-stimulated chondrocytes
Published in Biorheology (Oxford) (2008)“…In inflammatory conditions, chondrocytes produce large amounts of matrix metalloproteases (MMP) and nitric oxide (NO) thought to contribute to joint…”
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Separation and Quantification by Ion-Association Capillary Zone Electrophoresis of Unsaturated Disaccharide Units of Chondroitin Sulfates and Oligosaccharides Derived from Hyaluronan
Published in Analytical chemistry (Washington) (15-11-1998)“…An analytical method has been developed for assay of unsaturated disaccharides of chondroitin sulfates and of oligosaccharides (tetra- and hexasaccharides) of…”
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Oxidative stress-induced expression of HSP70 contributes to the inhibitory effect of 15d-PGJ2 on inducible prostaglandin pathway in chondrocytes
Published in Free radical biology & medicine (01-11-2014)“…The inhibitory effect of 15-deoxy-Δ(12,14)-prostaglandin J2 (15d-PGJ2) on proinflammatory gene expression has been extensively documented and frequently…”
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Modulation of IL‐1‐induced cartilage injury by NO synthase inhibitors: a comparative study with rat chondrocytes and cartilage entities
Published in British journal of pharmacology (01-08-1998)“…Nitric oxide (NO) is produced in diseased joints and may be a key mediator of IL‐1 effects on cartilage. Therefore, we compared the potency of new…”
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Modulation of IL-1 effects on cartilage by NO synthase inhibitors: pharmacological studies in rats
Published in Osteoarthritis and cartilage (01-07-1999)“…Objective To compare the ability of L-arginine (L-arg) analog nitric oxide synthase (NOS) inhibitors and isothioureas to restore the interleukin-1 (IL-1)…”
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Agonists of peroxisome proliferators-activated receptors (PPAR) alpha, beta/delta or gamma reduce transforming growth factor (TGF)-beta-induced proteoglycans' production in chondrocytes
Published in Osteoarthritis and cartilage (01-05-2007)“…To investigate the potency of selective agonists of peroxisome proliferators-activated receptors' (PPAR) isotypes (alpha, beta/delta or gamma) to modulate the…”
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miR-29b is overexpressed in osteoarthritic patients and targets type II collagen
Published in Osteoarthritis and cartilage (01-04-2012)Get full text
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Agonists of peroxisome proliferators-activated receptors (PPAR) α, β/δ or γ reduce transforming growth factor (TGF)-β-induced proteoglycans' production in chondrocytes
Published in Osteoarthritis and cartilage (01-05-2007)“…Summary Objective To investigate the potency of selective agonists of peroxisome proliferators-activated receptors' (PPAR) isotypes (α, β/δ or γ) to modulate…”
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208 CALCIUM INPUT MODULATES TRANSFORMING GROWTH FACTOR-β1-INDUCED EXPORT OF INORGANIC PYROPHOSPHATE BY CONTROLLING ANK EXPRESSION IN CHONDROCYTE: POSSIBLE INSIGHT TO THE PATHOPHYSIOLOGY OF HYPERCALCEMIA-RELATED CHONDROCALCINOSIS
Published in Osteoarthritis and cartilage (2010)Get full text
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