Search Results - "Journot, L."

hZAC Encodes a Zinc Finger Protein with Antiproliferative Properties and Maps to a Chromosomal Region Frequently Lost in Cancer by Varrault, A., Ciani, E., Apiou, F., Bilanges, B., Hoffmann, A., Pantaloni, C., Bockaert, J., Spengler, D., Journot, L.

“…We previously reported the identification of mZac, a novel mouse zinc finger protein that shared with p53 the ability to regulate concomitantly apoptosis and…”
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Zac1 is up-regulated in neural cells of the limbic system of mouse brain following seizures that provoke strong cell activation by Valente, T., Domínguez, M.-I., Bellmann, A., Journot, L., Ferrer, I., Auladell, C.

“…Zac1, a new zinc-finger protein that regulates both apoptosis and cell cycle arrest, is abundantly expressed in many proliferative/differentiation areas during…”
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LifeTime and improving European healthcare through cell-based interceptive medicine by Rajewsky, Nikolaus, Almouzni, Geneviève, Gorski, Stanislaw A., Aerts, Stein, Amit, Ido, Bertero, Michela G., Bock, Christoph, Bredenoord, Annelien L., Cavalli, Giacomo, Chiocca, Susanna, Clevers, Hans, De Strooper, Bart, Eggert, Angelika, Ellenberg, Jan, Fernández, Xosé M., Figlerowicz, Marek, Gasser, Susan M., Hubner, Norbert, Kjems, Jørgen, Knoblich, Jürgen A., Krabbe, Grietje, Lichter, Peter, Linnarsson, Sten, Marine, Jean-Christophe, Marioni, John C., Marti-Renom, Marc A., Netea, Mihai G., Nickel, Dörthe, Nollmann, Marcelo, Novak, Halina R., Parkinson, Helen, Piccolo, Stefano, Pinheiro, Inês, Pombo, Ana, Popp, Christian, Reik, Wolf, Roman-Roman, Sergio, Rosenstiel, Philip, Schultze, Joachim L., Stegle, Oliver, Tanay, Amos, Testa, Giuseppe, Thanos, Dimitris, Theis, Fabian J., Torres-Padilla, Maria-Elena, Valencia, Alfonso, Vallot, Céline, van Oudenaarden, Alexander, Vidal, Marie, Voet, Thierry

“…Here we describe the LifeTime Initiative, which aims to track, understand and target human cells during the onset and progression of complex diseases, and to…”
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A Novel Tetracycline-Dependent Expression Vector with Low Basal Expression and Potent Regulatory Properties in Various Mammalian Cell Lines by Hoffmann, Anke, Villalba, Martin, Journot, Laurent, Spengler, Dietmar

“…The tetracycline-dependent expression system has gained increasing popularity for the expression of any gene of interest. Careful choice of the expression…”
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Deletion within the amino-terminal region of Gs alpha impairs its ability to interact with beta gamma subunits and to activate adenylate cyclase by Journot, L, Pantaloni, C, Bockaert, J, Audigier, Y

“…Proteolytic experiments performed on transducin and Go alpha subunit strongly suggest that the amino-terminal residues of the alpha chain are involved in the…”
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Differential signal transduction by six splice variants of the pituitary adenylate cyclase-activating peptide (PACAP) receptor by Journot, L, Waeber, C, Pantaloni, C, Holsboer, F, Seeburg, P H, Bockaert, J, Spengler, D

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Transfection of human 5-hydroxytryptamine1A receptors in NIH-3T3 fibroblasts: effects of increasing receptor density on the coupling of 5-hydroxytryptamine1A receptors to adenylyl cyclase by Varrault, A, Journot, L, Audigier, Y, Bockaert, J

“…Human serotonin [5-hydroxytryptamine (5-HT)1A] receptors have been transfected in NIH-3T3 cells, and their pharmacology and coupling to adenylyl cyclase have…”
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PACAP/VIP receptor subtypes, signal transducers, and effectors in pituitary cells by Hezareh, M, Journot, L, Bépoldin, L, Schlegel, W, Rawlings, S R

“…Rat anterior pituitary tissue expresses mRNA for PVR1 and PVR3, as well as a low level of PVR2. The PVR1 appears to be highly expressed in gonadotroph-like…”
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An islet activating protein-sensitive G protein is involved in dopamine inhibition of angiotensin and thyrotropin-releasing hormone-stimulated inositol phosphate production in anterior pituitary cells by Journot, L, Homburger, V, Pantaloni, C, Priam, M, Bockaert, J, Enjalbert, A

“…In primary culture of anterior pituitary cells, dopamine inhibited the angiotensin (AII)-stimulated inositol phosphate production by 28 +/- 2.5% (n = 14), with…”
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The Carboxy-Terminal Domain of Gsα Is Necessary for Anchorage of the Activated Form in the Plasma Membrane by Audigier, Y., Journot, L., Pantaloni, C., Bockaert, J.

“…GTP-binding proteins which participate in signal transduction share a common heterotrimeric structure of the αβγ-type. In the activated state, the α subunit…”
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Mutation of valine residue unique to alpha subunit of Gs abolishes activation by DEVIC, E, JOURNOT, L, PANTALONI, C, BOCKAERT, J, AUDIGIER, Y

“…We recently characterized a decapeptide sequence (residues 367-376) that is important for the membrane association of the activated alpha subunit of Gs. We…”
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Phosphorylation of Bid by Casein Kinases I and II Regulates Its Cleavage by Caspase 8 by Desagher, Solange, Osen-Sand, Astrid, Montessuit, Sylvie, Magnenat, Edith, Vilbois, Francis, Hochmann, Alena, Journot, Laurent, Antonsson, Bruno, Martinou, Jean-Claude

“…Bid plays an essential role in Fas-mediated apoptosis of the so-called type II cells. In these cells, following cleavage by caspase 8, the C-terminal fragment…”
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Reconstitution of cyc- S49 membranes by in vitro translated Gsα: membrane anchorage and functional implications by JOURNOT, L, BOCKAERT, J, AUDIGIER, Y

“…After ADP-ribosylation by cholera toxin which promotes dissociation of the subunits, the alpha-subunit of Gs (Gs alpha) remained strongly associated with…”
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Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP-38) Protects Cerebellar Granule Neurons from Apoptosis by Activating the Mitogen-Activated Protein Kinase (MAP Kinase) Pathway by Villalba, Martin, Bockaert, Joel, Journot, Laurent

“…Pituitary adenylate cyclase-activating polypeptides (PACAP-27 and PACAP-38) are neuropeptides of the vasoactive intestinal polypeptide (VIP)/secretin/glucagon…”
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International Union of Pharmacology. XVIII. Nomenclature of receptors for vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide by Harmar, A J, Arimura, A, Gozes, I, Journot, L, Laburthe, M, Pisegna, J R, Rawlings, S R, Robberecht, P, Said, S I, Sreedharan, S P, Wank, S A, Waschek, J A

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Amino acids 367-376 of the Gs alpha subunit induce membrane association when fused to soluble amino-terminal deleted Gi1 alpha subunit by JOURNOT, L, PANTALONI, C, POUL, M.-A, MAZARGUIL, H, BOCKAERT, J, AUDIGIER, Y

“…Signal transduction GTP-binding proteins are tightly associated with plasma membrane. In the resting state, the anchorage of the alpha subunit could be…”
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Dissociation between Light-Induced Phase Shift of the Circadian Rhythm and Clock Gene Expression in Mice Lacking the Pituitary Adenylate Cyclase Activating Polypeptide Type 1 Receptor by Hannibal, Jens, Jamen, Francoise, Nielsen, Harriette S, Journot, Laurant, Brabet, Philippe, Fahrenkrug, Jan

“…The circadian clock located in the suprachiasmatic nucleus (SCN) organizes autonomic and behavioral rhythms into a near 24 hr time that is adjusted daily to…”
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Differential signal transduction by five splice variants of the PACAP receptor by Spongier, Dietmar, Waeber, Christian, Pantaloni, Colette, Holsboer, Florian, Bockaert, Joël, Seeburgt, Peter H, Journot, Laurent

“…The two forms of pituitary adenylyl cyclase-activating polypeptide (PACAP-27 and -38) are neuropeptides of the secretin/glucagon/vasoactive intestinal…”
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Regulation of apoptosis and cell cycle arrest by Zac1, a novel zinc finger protein expressed in the pituitary gland and the brain by Spengler, Dietmar, Villalba, Martin, Hoffmann, Anke, Pantaloni, Colette, Houssami, Souheir, Bockaert, Joel, Journot, Laurent

“…The proliferation rate of a cell population reflects a balance between cell division, cell cycle arrest, differentiation and apoptosis. The regulation of these…”
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MACVIA-LR, Reference site of the European Innovation Partnership on Active and Healthy Ageing (EIP on AHA) in Languedoc Roussillon by Bousquet, J, Bourquin, C, Augé, P, Domy, P, Bringer, J, Camuzat, T, Best, N, Jonquet, O, de la Coussaye, J.E, Blain, H, Giraudeau, N, Hève, D, Jeandel, C, Laffont, I, Larrey, D, Laurent, C, Pélissier, J.Y, Radier-Pontal, F, Royère, E, Bedbrook, A, Abecassis, F, Albert, S, Arnavieilhe, S, Aubas, P, Badin, M, Battesti, M.P, Bernard, P.L, Berthe, J, Bockaert, J, Bourdin, A, Bourrain, J.L, Bourrel, G, Burille, J, Caimmi, D, Camu, W, Cavalli, G, Chiron, R, Combe, B, Costa, D.J, Costa, P, Courtet, P, Daien, C, Danko, M, Dauzat, M, David, M, Demoly, P, Dujols, P, Dupeyron, A, Engberink, O, Hoa, D, Jacquemin, S, Gris, J.C, Jakovenko, D, Jorgensen, C, Journot, L, Kaczorek, M, Laune, D, Léglise, M.S, Le Quellec, A, Lehmann, S, Marmelat, V, Matheron, A, Mercier, G, Messner, P, Meunier, C, Morel, J, Nérin, P, Ninot, G, Nouvel, F, Ortiz, J.P, Pasquié, J.L, Pastor, E, Perrey, S, Pers, Y.M, Picot, M.C, Pin, J.P, Portejoie, F, Quéré, I, Raffort, N, Ramdani, S, Reynes, J, Rédini-Martinez, I, Richard, S, Ritchie, K, Rolland, C, Salvat, A, Savy, J.L, Strubel, D, Tassery, H, Torre, K, Van de Perre, P, Vasquez, X, Vian, L, Vialla, F, Villain, M, Ankri, J, Berrut, G, Joël, M.E, Vellas, B, Mercier, J

“…Abstract The Région Languedoc-Roussillon is the umbrella organisation for an interconnected and integrated project on AHA covering the 3 pillars of the…”
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