Search Results - "Journe, Clement"
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Bimodal Fucoidan-Coated Zinc Oxide/Iron Oxide-Based Nanoparticles for the Imaging of Atherothrombosis
Published in Molecules (Basel, Switzerland) (08-03-2019)“…A polyol method was used to obtain ultrasmall ZnO nanoparticles (NPs) doped with iron ions and coated with a low molecular weight fucoidan in order to perform…”
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Non-immunogenic dextran-coated superparamagnetic iron oxide nanoparticles: a biocompatible, size-tunable contrast agent for magnetic resonance imaging
Published in International journal of nanomedicine (01-01-2017)“…Iron oxide-based contrast agents have been in clinical use for magnetic resonance imaging (MRI) of lymph nodes, liver, intestines, and the cardiovascular…”
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Gd(DOTA)-grafted submicronic polysaccharide-based particles functionalized with fucoidan as potential MR contrast agent able to target human activated platelets
Published in Carbohydrate polymers (01-10-2020)“…[Display omitted] •Polysaccharide matrix contained both fucoidan and dextran gadolinium macrocomplex.•A simple and green water-in-oil…”
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Porphyromonas gingivalis participates in pathogenesis of human abdominal aortic aneurysm by neutrophil activation. Proof of concept in rats
Published in PloS one (13-04-2011)“…Abdominal Aortic Aneurysms (AAAs) represent a particular form of atherothrombosis where neutrophil proteolytic activity plays a major role. We postulated that…”
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Neurologic Complications of Infective Endocarditis: A Joint Model for a Septic Thromboembolism and Inflammatory Small Vessel Disease
Published in Critical care medicine (01-08-2019)“…OBJECTIVES:Embolic events from vegetations are commonly accepted as the main mechanism involved in neurologic complications of infective endocarditis. The…”
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Efficacy of intra-tendinous injection of platelet-rich plasma in treating tendinosis: comprehensive assessment of a rat model
Published in European radiology (01-10-2013)“…Objectives To assess the potential of intra-tendinous injection of platelet rich plasma (PRP) to treat tendinosis (T+) in a rat model of patellar and Achilles…”
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Exacerbation of thromboinflammation by JAK2V617F mutation worsens the prognosis of cerebral venous sinus thrombosis
Published in Blood advances (25-06-2024)“…•JAK2V617F mutation contributes to hemorrhagic lesions and to mortality in an experimental model of cerebral venous thrombosis.•JAK2V617F mutation exacerbates…”
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Disruption of the Phosphate Transporter Pit1 in Hepatocytes Improves Glucose Metabolism and Insulin Signaling by Modulating the USP7/IRS1 Interaction
Published in Cell reports (Cambridge) (06-09-2016)“…The liver plays a central role in whole-body lipid and glucose homeostasis. Increasing dietary fat intake results in increased hepatic fat deposition, which is…”
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Exacerbation of Thromboinflammation by Hyperglycemia Precipitates Cerebral Infarct Growth and Hemorrhagic Transformation
Published in Stroke (1970) (01-07-2017)“…BACKGROUND AND PURPOSE—Admission hyperglycemia is associated with a poor outcome in acute ischemic stroke. How hyperglycemia impacts the pathophysiology of…”
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Tolerogenic Iron Oxide Nanoparticles in Type 1 Diabetes: Biodistribution and Pharmacokinetics Studies in Nonobese Diabetic Mice
Published in Small (Weinheim an der Bergstrasse, Germany) (01-10-2018)“…Nanoparticle (NP) administration is among the most attractive approaches to exploit the synergy of different copackaged molecules for the same target. In this…”
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Inhibition of ERK1/2 Phosphorylation: A New Strategy to Stimulate Elastogenesis in the Aorta
Published in Hypertension (Dallas, Tex. 1979) (01-08-2014)“…Haploinsufficiency of elastin leads, in more than half of patients with Williams–Beuren syndrome, to development of supravalvular aortic stenosis and…”
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Dual effect of cardiac FKBP12.6 overexpression on excitation-contraction coupling and the incidence of ventricular arrhythmia depending on its expression level
Published in Journal of molecular and cellular cardiology (01-03-2024)“…FKBP12.6, a binding protein to the immunosuppressant FK506, which also binds the ryanodine receptor (RyR2) in the heart, has been proposed to regulate RyR2…”
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Acceleration of tendon healing using US guided intratendinous injection of bevacizumab: First pre-clinical study on a murine model
Published in European journal of radiology (01-12-2013)“…Abstract Purpose Tendinopathy shows early disorganized collagen fibers with neo-angiogenesis on histology. Peri-tendinous injection of corticosteroid is the…”
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Perfusion of MC3T3E1 Preosteoblast Spheroids within Polysaccharide-Based Hydrogel Scaffolds: An Experimental and Numerical Study at the Bioreactor Scale
Published in Bioengineering (Basel) (01-07-2023)“…The traditional 3D culture systems in vitro lack the biological and mechanical spatiotemporal stimuli characteristic to native tissue development. In our…”
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Low Levels of Low-Density Lipoprotein-C Associated With Proprotein Convertase Subtilisin Kexin 9 Inhibition Do Not Increase the Risk of Hemorrhagic Transformation
Published in Stroke (1970) (01-10-2014)“…BACKGROUND AND PURPOSE—Low levels of low-density lipoprotein-cholesterol (LDL-C) are suspected to be associated with a risk of hemorrhagic transformation after…”
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Synthesis and activation of an iron oxide immobilized drug-mimicking reporter under conventional and pulsed X-ray irradiation conditions
Published in RSC advances (21-01-2020)“…An efficient nano-sized delivery system is presented here allowing the immobilized, picolinium-tethered organic ligand to be released by X-ray irradiation. A…”
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In vitro and in vivo hemocompatibility evaluation of a new dermatan sulfate-modified PET patch for vascular repair surgery
Published in Journal of biomedical materials research. Part B, Applied biomaterials (01-10-2017)“…The development of new vascular devices requires to study the effects of materials on blood cells and on coagulation, both in vitro and in vivo. In this study,…”
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Leukocyte mimetic polysaccharide microparticles tracked in vivo on activated endothelium and in abdominal aortic aneurysm
Published in Acta biomaterialia (01-08-2014)“…[Display omitted] We have developed injectable microparticles functionalized with fucoidan, in which sulfated groups mimic the anchor sites of P-selectin…”
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A Novel Mouse Model for Cerebral Venous Sinus Thrombosis
Published in Translational stroke research (01-12-2021)“…Cerebral venous sinus thrombosis (CVST) is an uncommon cause of stroke resulting in parenchymal injuries associated with heterogeneous clinical symptoms and…”
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