Search Results - "Journal of physiology and pharmacology : an official journal of the Polish Physiological Society"

The importance of selected markers of inflammation and blood-brain barrier damage for short-term ischemic stroke prognosis by Lasek-Bal, A, Jedrzejowska-Szypulka, H, Student, S, Warsz-Wianecka, A, Zareba, K, Puz, P, Bal, W, Pawletko, K, Lewin-Kowalik, J

“…Acute cerebral ischemia triggers local and systemic immune response. The aims of this project was to assess the blood serum concentration of the markers of…”
Get more information

Lipid peroxidation, reactive oxygen species and antioxidative factors in the pathogenesis of gastric mucosal lesions and mechanism of protection against oxidative stress - induced gastric injury by Kwiecien, S, Jasnos, K, Magierowski, M, Sliwowski, Z, Pajdo, R, Brzozowski, B, Mach, T, Wojcik, D, Brzozowski, T

“…The gastric mucosa plays an important role in the physiological function of the stomach. This mucosa acts as gastric barrier, which protects deeper located…”
Get more information

Stress and the gut: pathophysiology, clinical consequences, diagnostic approach and treatment options by Konturek, Peter C, Brzozowski, T, Konturek, S J

“…Stress, which is defined as an acute threat to homeostasis, shows both short- and long-term effects on the functions of the gastrointestinal tract. Exposure to…”
Get more information

Sperm mitochondrial dysfunction and oxidative stress as possible reasons for isolated asthenozoospermia by Nowicka-Bauer, K, Lepczynski, A, Ozgo, M, Kamieniczna, M, Fraczek, M, Stanski, L, Olszewska, M, Malcher, A, Skrzypczak, W, Kurpisz, M K

“…Reduced sperm motility, defined as asthenozoospermia, is a frequent cause of male infertility, and is mainly connected with the dysfunction of sperm…”
Get more information

New insight into the direct anti-inflammatory activity of a myokine irisin against proinflammatory activation of adipocytes. Implication for exercise in obesity by Mazur-Bialy, A I, Bilski, J, Pochec, E, Brzozowski, T

“…A biological activity of myokine irisin, has been intensively investigated in the context of a browning process occurring in white adipose tissue, but its role…”
Get more information

Crossfit training changes brain-derived neurotrophic factor and irisin levels at rest, after wingate and progressive tests, and improves aerobic capacity and body composition of young physically active men and women by Murawska-Cialowicz, E, Wojna, J, Zuwala-Jagiello, J

“…Brain-derived neurotrophic factor (BDNF) is a protein that stimulates processes of neurogenesis, the survival of neurons and microglia, stimulates…”
Get more information

Artificial saliva and its use in biological experiments by J Pytko-Polonczyk, J, Jakubik, A, Przeklasa-Bierowiec, A, Muszynska, B

“…Examination of dental materials and their properties at the initial stage of the digestive process requires the development of conditions that mimic the…”
Get more information

Emerging role of fecal microbiota therapy in the treatment of gastrointestinal and extra-gastrointestinal diseases by Konturek, P C, Haziri, D, Brzozowski, T, Hess, T, Heyman, S, Kwiecien, S, Konturek, S J, Koziel, J

“…In the recent decade our understanding of the role of the human gut microbiome has been revolutionized by advances in development of molecular methods…”
Get more information

The effect of reactive oxygen species on the synthesis of prostanoids from arachidonic acid by Korbecki, J, Baranowska-Bosiacka, I, Gutowska, I, Chlubek, D

“…Reactive oxygen species (ROS), such as hydrogen peroxide, superoxide anion radical or hydroxyl radical, play an important role in inflammation processes as…”
Get more information

The lactate receptor (HCAR1/GPR81) contributes to doxorubicin chemoresistance via ABCB1 transporter up-regulation in human cervical cancer HeLa cells by Wagner, W, Kania, K D, Blauz, A, Ciszewski, W M

“…The lactate receptor, also known as hydroxycarboxylic acid receptor 1 (HCAR1/GPR81), plays a vital role in cancer biology. Recently, HCAR1 was reported to…”
Get more information

The inhibitory effect of polyphenols on human gut microbiota by Duda-Chodak, A

“…The intestinal microbiota (IM) is responsible for metabolism of many compounds provided in the diet, such as polyphenols, increasing their bioavailability…”
Get more information

Kaempferol protects against streptozotocin-induced diabetic cardiomyopathy in rats by a hypoglycemic effect and upregulating SIRT1 by Alshehri, A S, El-Kott, A F, Eleawa, S M, El-Gerbed, M S A, Khalifa, H S, El-Kenawy, A E, Albadrani, G M, Abdel-Daim, M M

“…This study investigated if kaempferol could attenuate the oxidative, inflammatory, and fibrotic damage of the left ventricles (LVs) in streptozotocin…”
Get more information

Role of glutathione metabolism and glutathione-related antioxidant defense systems in hypertension by Robaczewska, J, Kedziora-Kornatowska, K, Kozakiewicz, M, Zary-Sikorska, E, Pawluk, H, Pawliszak, W, Kedziora, J

“…The risk of developing chronic hypertension increases with age. Among others factors, increased oxidative stress is a well-recognized etiological factor for…”
Get more information

Hippo pathway - brief overview of its relevance in cancer by Zygulska, A L, Krzemieniecki, K, Pierzchalski, P

“…The Hippo pathway is the major regulator of organ growth and proliferation. Described initially in Drosophila, it is now recognized as one of the most…”
Get more information

Essentiality and toxicity of vanadium supplements in health and pathology by Gruzewska, K, Michno, A, Pawelczyk, T, Bielarczyk, H

“…The biological properties of vanadium complexes have become an object of interest due to their therapeutic potential in several diseases. However, the…”
Get more information

Intestinal microbiota, intestinal permeability and the urogenital tract: is there a pathophysiological link? by Priadko, K, Romano, L, Olivieri, S, Romeo, M, Barone, B, Sciorio, C, Spirito, L, Morelli, M, Crocetto, F, Arcaniolo, D, Mirone, V, Romano, M, Napolitano, L

“…Human gut microbiome is related to different clinical conditions and diseases. Recently several hypotheses have been theorized about a link between gut…”
Get more information

Aldosterone and mineralocorticoid receptors in regulation of the cardiovascular system and pathological remodelling of the heart and arteries by Sztechman, D, Czarzasta, K, Cudnoch-Jedrzejewska, A, Szczepanska-Sadowska, E, Zera, T

“…In the review we discuss the role of mineralocorticoid receptors (MRs) in regulation and pathological remodelling of the cardiovascular system and the…”
Get more information

Moderate-intensity interval training increases serum brain-derived neurotrophic factor level and decreases inflammation in Parkinson's disease patients by Zoladz, J A, Majerczak, J, Zeligowska, E, Mencel, J, Jaskolski, A, Jaskolska, A, Marusiak, J

“…It has been demonstrated that physical training increases serum brain-derived neurotrophic factor (BDNF) in healthy people. The aim of this study was to…”
Get more information

Overview of the role of vitamins and minerals on the kynurenine pathway in health and disease by Majewski, M, Kozlowska, A, Thoene, M, Lepiarczyk, E, Grzegorzewski, W J

“…The kynurenine pathway (KP) of L-tryptophan metabolism produces several neuroactive metabolites with an amino acid structure. These metabolites may play an…”
Get more information

Successful therapy of Clostridium difficile infection with fecal microbiota transplantation by Konturek, P C, Koziel, J, Dieterich, W, Haziri, D, Wirtz, S, Glowczyk, I, Konturek, K, Neurath, M F, Zopf, Y

“…Clostridium difficile infection (CDI) is the most common cause of infectious diarrhea and represents an important burden for healthcare worldwide. Symptoms of…”
Get more information