Search Results - "Journal of neuro-oncology"

A review of glioblastoma immunotherapy by Medikonda, Ravi, Dunn, Gavin, Rahman, Maryam, Fecci, Peter, Lim, Michael

“…Introduction Glioblastoma is a very aggressive cancer with dismal prognosis despite standard of care including surgical resection, radiation therapy, and…”
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Immune suppression in gliomas by Grabowski, Matthew M., Sankey, Eric W., Ryan, Katherine J., Chongsathidkiet, Pakawat, Lorrey, Selena J., Wilkinson, Daniel S., Fecci, Peter E.

“…Introduction The overall survival in patients with gliomas has not significantly increased in the modern era, despite advances such as immunotherapy. This is…”
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5-ALA and FDA approval for glioma surgery by Hadjipanayis, Constantinos G., Stummer, Walter

“…The US Food and Drug Administration (FDA) approved 5-aminolevulinic acid (5-ALA; Gleolan ® ; photonamic GmbH and Co. KG) for use as an intraoperative optical…”
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Molecular markers in glioma by Ludwig, Kirsten, Kornblum, Harley I.

“…Gliomas are the most malignant and aggressive form of brain tumors, and account for the majority of brain cancer related deaths. Malignant gliomas, including…”
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5-aminolevulinic acid photodynamic therapy for the treatment of high-grade gliomas by Mahmoudi, K., Garvey, K. L., Bouras, A., Cramer, G., Stepp, H., Jesu Raj, J. G., Bozec, D., Busch, T. M., Hadjipanayis, C. G.

“…Introduction Photodynamic therapy (PDT) is a two-step treatment involving the administration of a photosensitive agent followed by its activation at a specific…”
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Trends in glioblastoma: outcomes over time and type of intervention: a systematic evidence based analysis by Marenco-Hillembrand, Lina, Wijesekera, Olindi, Suarez-Meade, Paola, Mampre, David, Jackson, Christina, Peterson, Jennifer, Trifiletti, Daniel, Hammack, Julie, Ortiz, Kyle, Lesser, Elizabeth, Spiegel, Matthew, Prevatt, Calder, Hawayek, Maria, Quinones-Hinojosa, Alfredo, Chaichana, Kaisorn L.

“…Introduction Despite aggressive treatment with chemoradiotherapy and maximum surgical resection, survival in patients with glioblastoma (GBM) remains poor…”
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Epidemiology of glioma: clinical characteristics, symptoms, and predictors of glioma patients grade I–IV in the the Danish Neuro-Oncology Registry by Rasmussen, Birthe Krogh, Hansen, Steinbjørn, Laursen, René J., Kosteljanetz, Michael, Schultz, Henrik, Nørgård, Bente Mertz, Guldberg, Rikke, Gradel, Kim Oren

“…In this national population-based study of glioma, we present epidemiologic data on incidence, demographics, survival, clinical characteristics and symptoms,…”
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Biogenesis of extracellular vesicles (EV): exosomes, microvesicles, retrovirus-like vesicles, and apoptotic bodies by Akers, Johnny C., Gonda, David, Kim, Ryan, Carter, Bob S., Chen, Clark C.

“…Recent studies suggest both normal and cancerous cells secrete vesicles into the extracellular space. These extracellular vesicles (EVs) contain materials that…”
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Pediatric and adult H3 K27M-mutant diffuse midline glioma treated with the selective DRD2 antagonist ONC201 by Chi, Andrew S., Tarapore, Rohinton S., Hall, Matthew D., Shonka, Nicole, Gardner, Sharon, Umemura, Yoshie, Sumrall, Ashley, Khatib, Ziad, Mueller, Sabine, Kline, Cassie, Zaky, Wafik, Khatua, Soumen, Weathers, Shiao-Pei, Odia, Yazmin, Niazi, Toba N., Daghistani, Doured, Cherrick, Irene, Korones, David, Karajannis, Matthias A., Kong, Xiao-Tang, Minturn, Jane, Waanders, Angela, Arillaga-Romany, Isabel, Batchelor, Tracy, Wen, Patrick Y., Merdinger, Krystal, Schalop, Lee, Stogniew, Martin, Allen, Joshua E., Oster, Wolfgang, Mehta, Minesh P.

“…Background H3 K27M-mutant diffuse midline glioma is a fatal malignancy with no proven medical therapies. The entity predominantly occurs in children and young…”
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Pseudoprogression, radionecrosis, inflammation or true tumor progression? challenges associated with glioblastoma response assessment in an evolving therapeutic landscape by Ellingson, Benjamin M., Chung, Caroline, Pope, Whitney B., Boxerman, Jerrold L., Kaufmann, Timothy J.

“…The wide variety of treatment options that exist for glioblastoma, including surgery, ionizing radiation, anti-neoplastic chemotherapies, anti-angiogenic…”
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Increased compliance with tumor treating fields therapy is prognostic for improved survival in the treatment of glioblastoma: a subgroup analysis of the EF-14 phase III trial by Toms, S. A., Kim, C. Y., Nicholas, G., Ram, Z.

“…Background Tumor treating fields (TTFields) is a non-invasive, antimitotic therapy. In the EF-14 phase 3 trial in newly diagnosed glioblastoma, TTFields plus…”
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Efficacy and safety of intratumoral thermotherapy using magnetic iron-oxide nanoparticles combined with external beam radiotherapy on patients with recurrent glioblastoma multiforme by Maier-Hauff, Klaus, Ulrich, Frank, Nestler, Dirk, Niehoff, Hendrik, Wust, Peter, Thiesen, Burghard, Orawa, Helmut, Budach, Volker, Jordan, Andreas

“…Therapy options at the time of recurrence of glioblastoma multiforme are often limited. We investigated whether treatment with a new intratumoral thermotherapy…”
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Machine learning reveals multimodal MRI patterns predictive of isocitrate dehydrogenase and 1p/19q status in diffuse low- and high-grade gliomas by Zhou, Hao, Chang, Ken, Bai, Harrison X., Xiao, Bo, Su, Chang, Bi, Wenya Linda, Zhang, Paul J., Senders, Joeky T., Vallières, Martin, Kavouridis, Vasileios K., Boaro, Alessandro, Arnaout, Omar, Yang, Li, Huang, Raymond Y.

“…Purpose Isocitrate dehydrogenase ( IDH ) and 1p19q codeletion status are importantin providing prognostic information as well as prediction of treatment…”
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Maximizing safe resection of low- and high-grade glioma by Hervey-Jumper, Shawn L., Berger, Mitchel S.

“…Surgical resection plays a central role in the management of gliomas. In this study, we review the evidence in support of extent of resection to improve…”
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Long-term risk of radionecrosis and imaging changes after stereotactic radiosurgery for brain metastases by Kohutek, Zachary A., Yamada, Yoshiya, Chan, Timothy A., Brennan, Cameron W., Tabar, Viviane, Gutin, Philip H., Jonathan Yang, T., Rosenblum, Marc K., Ballangrud, Åse, Young, Robert J., Zhang, Zhigang, Beal, Kathryn

“…Radionecrosis is a well-characterized effect of stereotactic radiosurgery (SRS) and is occasionally associated with serious neurologic sequelae. Here, we…”
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Treatment outcome of patients with recurrent glioblastoma multiforme: a retrospective multicenter analysis by van Linde, Myra E., Brahm, Cyrillo G., de Witt Hamer, Philip C., Reijneveld, Jaap C., Bruynzeel, Anna M. E., Vandertop, W. Peter, van de Ven, Peter M., Wagemakers, Michiel, van der Weide, Hiske L., Enting, Roelien H., Walenkamp, Annemiek M. E., Verheul, Henk M. W.

“…Glioblastoma multiforme (GBM) universally recurs with dismal prognosis. We evaluated the efficacy of standard treatment strategies for patients with recurrent…”
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Combined intracavitary thermotherapy with iron oxide nanoparticles and radiotherapy as local treatment modality in recurrent glioblastoma patients by Grauer, Oliver, Jaber, Mohammed, Hess, Katharina, Weckesser, Matthias, Schwindt, Wolfram, Maring, Stephan, Wölfer, Johannes, Stummer, Walter

“…Background There is an increasing interest in local tumor ablative treatment modalities that induce immunogenic cell death and the generation of antitumor…”
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Re-irradiation for recurrent glioblastoma (GBM): a systematic review and meta-analysis by Kazmi, Farasat, Soon, Yu Yang, Leong, Yiat Horng, Koh, Wee Yao, Vellayappan, Balamurugan

“…Purpose To determine the efficacy and toxicity of re-irradiation for patients with recurrent GBM. Materials and methods We searched various biomedical…”
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Glioblastoma survival in the United States before and during the temozolomide era by Johnson, Derek R., O’Neill, Brian Patrick

“…The standard-of-care treatment for newly diagnosed glioblastoma changed in 2005, when radiation therapy plus temozolomide chemotherapy replaced radiation…”
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The role of bevacizumab in the treatment of glioblastoma by Diaz, Roberto Jose, Ali, Sheikh, Qadir, Mehreen Gull, De La Fuente, Macarena I., Ivan, Michael E., Komotar, Ricardo J.

“…Bevacizumab has been used in patients with GBM as a salvage therapy since its approval in the United States for recurrent GBM in 2009. In order to review the…”
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