Search Results - "Journal of industrial microbiology & biotechnology"

Natural product discovery: past, present, and future by Katz, Leonard, Baltz, Richard H

“…Microorganisms have provided abundant sources of natural products which have been developed as commercial products for human medicine, animal health, and plant…”
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Natural product drug discovery in the genomic era: realities, conjectures, misconceptions, and opportunities by Baltz, Richard H.

“…Natural product discovery from microorganisms provided important sources for antibiotics, anti-cancer agents, immune-modulators, anthelminthic agents, and…”
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Synthetic microbial consortia for biosynthesis and biodegradation: promises and challenges by Che, Shun, Men, Yujie

“…Functional differentiation and metabolite exchange enable microbial consortia to perform complex metabolic tasks and efficiently cycle the nutrients. Inspired…”
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Microbial platforms to produce commercially vital carotenoids at industrial scale: an updated review of critical issues by Saini, Ramesh Kumar, Keum, Young-Soo

“…Carotenoids are a diverse group of isoprenoid pigments that play crucial roles in plants, animals, and microorganisms, including body pigmentation,…”
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Microbial genome mining for accelerated natural products discovery: is a renaissance in the making? by Bachmann, Brian O, Van Lanen, Steven G, Baltz, Richard H

“…Microbial genome mining is a rapidly developing approach to discover new and novel secondary metabolites for drug discovery. Many advances have been made in…”
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Genetic tools for reliable gene expression and recombineering in Pseudomonas putida by Cook, Taylor B., Rand, Jacqueline M., Nurani, Wasti, Courtney, Dylan K., Liu, Sophia A., Pfleger, Brian F.

“…Pseudomonas putida is a promising bacterial host for producing natural products, such as polyketides and nonribosomal peptides. In these types of projects,…”
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Genetic manipulation of secondary metabolite biosynthesis for improved production in Streptomyces and other actinomycetes by Baltz, Richard H

“…Actinomycetes continue to be important sources for the discovery of secondary metabolites for applications in human medicine, animal health, and crop…”
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Monascus secondary metabolites: production and biological activity by Patakova, Petra

“…The genus Monascus, comprising nine species, can reproduce either vegetatively with filaments and conidia or sexually by the formation of ascospores. The most…”
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Industrial production of recombinant therapeutics in Escherichia coli and its recent advancements by Huang, Chung-Jr, Lin, Henry, Yang, Xiaoming

“…Nearly 30% of currently approved recombinant therapeutic proteins are produced in Escherichia coli. Due to its well-characterized genetics, rapid growth and…”
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many roles of glutamate in metabolism by Walker, Mark C, van der Donk, Wilfred A

“…The amino acid glutamate is a major metabolic hub in many organisms and as such is involved in diverse processes in addition to its role in protein synthesis…”
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Genome mining for lasso peptides: past, present, and future by Cheung-Lee, Wai Ling, Link, A. James

“…Over the course of roughly a decade, the lasso peptide field has been transformed. Whereas new compounds were discovered infrequently via activity-driven…”
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Genome mining for drug discovery: progress at the front end by Baltz, Richard H

“…Microbial genome mining for drug discovery and development has been accelerating in recent years, driven by technical advancements in genome sequencing,…”
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DyP-type peroxidases: a promising and versatile class of enzymes by Colpa, Dana I, Fraaije, Marco W, van Bloois, Edwin

“…DyP peroxidases comprise a novel superfamily of heme-containing peroxidases, which is unrelated to the superfamilies of plant and animal peroxidases. These…”
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Metagenomic applications in environmental monitoring and bioremediation by Techtmann, Stephen M., Hazen, Terry C.

“…With the rapid advances in sequencing technology, the cost of sequencing has dramatically dropped and the scale of sequencing projects has increased…”
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Enzymatic processing of lignocellulosic biomass: principles, recent advances and perspectives by Østby, Heidi, Hansen, Line Degn, Horn, Svein J., Eijsink, Vincent G. H., Várnai, Anikó

“…Efficient saccharification of lignocellulosic biomass requires concerted development of a pretreatment method, an enzyme cocktail and an enzymatic process, all…”
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Advances in microbial culturing conditions to activate silent biosynthetic gene clusters for novel metabolite production by Tomm, Hailey A., Ucciferri, Lorena, Ross, Avena C.

“…Natural products (NPs) produced by bacteria and fungi are often used as therapeutic agents due to their complex structures and wide range of bioactivities…”
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Tailor-made transcriptional biosensors for optimizing microbial cell factories by De Paepe, Brecht, Peters, Gert, Coussement, Pieter, Maertens, Jo, De Mey, Marjan

“…Monitoring cellular behavior and eventually properly adapting cellular processes is key to handle the enormous complexity of today’s metabolic engineering…”
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Genome mining of the Streptomyces avermitilis genome and development of genome-minimized hosts for heterologous expression of biosynthetic gene clusters by Ikeda, Haruo, Shin-ya, Kazuo, Omura, Satoshi

“…To date, several actinomycete genomes have been completed and annotated. Among them, Streptomyces microorganisms are of major pharmaceutical interest because…”
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Redox cofactor engineering in industrial microorganisms: strategies, recent applications and future directions by Liu, Jiaheng, Li, Huiling, Zhao, Guangrong, Caiyin, Qinggele, Qiao, Jianjun

“…NAD and NADP, a pivotal class of cofactors, which function as essential electron donors or acceptors in all biological organisms, drive considerable catabolic…”
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Metabolic engineering for improving l-tryptophan production in Escherichia coli by Niu, Hao, Li, Ruirui, Liang, Quanfeng, Qi, Qingsheng, Li, Qiang, Gu, Pengfei

“…l -Tryptophan is an important aromatic amino acid that is used widely in the food, chemical, and pharmaceutical industries. Compared with the traditional…”
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