Search Results - "Journal of heterocyclic chemistry"

Benzimidazole based derivatives as anticancer agents: Structure activity relationship analysis for various targets by Satija, Garvit, Sharma, Barkha, Madan, Anish, Iqubal, Ashif, Shaquiquzzaman, Mohammad, Akhter, Mymoona, Parvez, Suhel, Khan, Mohammad Ahmed, Alam, Mohammad Mumtaz

“…Benzimidazole, the benzo derivative of imidazole, is a class of bicyclic aromatic organic compound consisting of six‐membered benzene ring fused to…”
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New biologically potent benzimidazole‐based‐triazole derivatives as acetylcholinesterase and butyrylcholinesterase inhibitors along with molecular docking study by Khan, Yousaf, Rehman, Wajid, Hussain, Rafaqat, Khan, Shoaib, Malik, Aneela, Khan, Marwa, Liaqat, Anjum, Rasheed, Liaqat, Begum, Faiza, Fazil, Srosh, Khan, Imran, Abdellatif, Magda H.

“…A series of fifteen hybrid analogs (1–15) based on benzimidazole bearing triazole skeleton were synthesized and were evaluated for in vitro AChE and BuChE…”
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A review of recent synthetic strategies and biological activities of isoxazole by Pandhurnekar, Chandrashekhar P., Pandhurnekar, Himani C., Mungole, Arvind J., Butoliya, Suraj S., Yadao, Babita G.

“…Among different heterocyclic compounds, isoxazole and their analogues are very important classes of heterocyclic compounds as they display an extensive range…”
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A retrospect on antimicrobial potential of thiazole scaffold by Mishra, Isha, Mishra, Raghav, Mujwar, Somdutt, Chandra, Phool, Sachan, Neetu

“…Due to its appreciable diversity in biological actions, thiazole and its substituted components, a significant class of heterocyclic compounds has developed as…”
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Thiazolidinones: Synthesis, Reactivity, and Their Biological Applications by Nirwan, Sonam, Chahal, Varun, Kakkar, Rita

“…Thiazolidinone is a biologically important five‐membered heterocyclic ring having almost all types of biological activities. This review covers various types…”
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Coumarin–triazole Hybrids and Their Biological Activities by Fan, Yi‐Lei, Ke, Xing, Liu, Min

“…Hybridization is emerged as a promising strategy in the discovery of new drugs, especially these with complimentary activities and multiple pharmacological…”
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Biological importance of the indole nucleus in recent years: A comprehensive review by Sharma, Vikas, Kumar, Pradeep, Pathak, Devender

“…J. Heterocyclic Chem., (2010)…”
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Medicinal perspective of quinazolinone derivatives: Recent developments and structure–activity relationship studies by Wahan, Simranpreet K., Sharma, Bharti, Chawla, Pooja A.

“…Heterocyclic rings have long piqued the interest of medicinal chemists. Quinazolinone is a fused nitrogen‐based heterocyclic moiety. Some of quinazolinone…”
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Synthesis of heterocyclic compounds via Michael and Hantzsch reactions by Abdella, Amna M., Abdelmoniem, Amr M., Abdelhamid, Ismail A., Elwahy, Ahmed H. M.

“…Heterocycles represent the largest diversity of organic compounds with signifcant chemical, biomedical, and industrial applications. They exist in numerous…”
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Synthesis of pyrano[2,3‐c]pyrazoles: A review by Sikandar, Sana, Zahoor, Ameer Fawad

“…One‐pot synthesis of pyrano[2,3‐c]pyrazole derivatives via two or multicomponent condensation of β‐ketoesters, hydrazine monohydrate/phenyl hydrazine,…”
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Synthesis and antimicrobial activity of new 1,2,4‐triazole, 1,3,4‐oxadiazole, 1,3,4‐thiadiazole, thiopyrane, thiazolidinone, and azepine derivatives by Abu‐Hashem, Ameen Ali

“…4‐oxo‐4‐phenylbutanehydrazide 3 was reacted with aryl or alkyl isothiocyanates to give the corresponding N‐substituted‐2‐(4‐oxo‐4‐phenylbutanoyl)…”
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One‐pot synthesis and biological evaluation of novel 4‐[3‐fluoro‐4‐(morpholin‐4‐yl)]phenyl‐1H‐1,2,3‐triazole derivatives as potent antibacterial and anticancer agents by Narsimha, Sirassu, Nukala, Sathesh Kumar, Savitha Jyostna, T., Ravinder, M., Srinivasa Rao, M., Vasudeva Reddy, N.

“…In search of better antibacterial and anticancer agents, a series of novel 4‐[3‐fluoro‐4‐(morpholin‐4‐yl)]phenyl‐1H‐1,2,3‐triazole derivatives were synthesized…”
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Trifluorodiazoethane: A versatile building block to access trifluoromethylated heterocycles by Kumar, Anuj, Khan, Waqas Ahmad, Ahamad, Shakir, Mohanan, Kishor

“…Trifluoromethylated heterocycles have attracted remarkable interest in the last decades. The beneficial physicochemical and biological properties imparted by…”
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Quinolone–Triazole Hybrids and their Biological Activities by Xu, Jun‐Hao, Fan, Yi‐Lei, Zhou, Jin

“…Hybridization, a strategy based on the covalent fusion of two or more existing pharmacophores to create a single molecule with multiple mechanisms of action,…”
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Design, synthesis, anticancer, antibacterial, and antifungal evaluation of 4‐aminoquinoline‐1,3,5‐triazine derivatives by Bhat, Hans Raj, Masih, Anup, Shakya, Anshul, Ghosh, Surajit Kumar, Singh, Udaya Pratap

“…A series of 4‐aminoquinoline 1,3,5‐triazine derivatives were synthesized and evaluated for anticancer activity against cancer cell lines HeLa, MCF‐7, HL‐60,…”
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An operationally simple, one‐pot, convenient synthesis, and in vitro anti‐inflammatory activity of some new spirotriazolotriazine derivatives by El‐Saghier, Ahmed M., Enaili, Souhaila S., Abdou, Aly, Hamed, Amany M., Kadry, Asmaa M.

“…The wide biological actions of triazolotriazine hybrids, benzene‐sulfonamide derivatives, exhibit a good chance of displaying in vitro anti‐inflammatory…”
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Biological Potential of Thiazole Derivatives of Synthetic Origin by Mishra, Raghav, Sharma, Pramod Kumar, Verma, Prabhakar Kumar, Tomer, Isha, Mathur, Garima, Dhakad, Prashant Kumar

“…Thiazole and related nucleus are one of the most important potential entities in the largely growing chemical world of heterocyclic compounds exhibiting…”
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Oxazole and Isoxazole Chemistry in Crop Protection by Lamberth, Clemens

“…An overview is given of the significance of the oxazole and isoxazole scaffolds in crop protection chemistry. The main herbicidally, fungicidally, and…”
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Heterocyclic compounds as antiviral drugs: Synthesis, structure–activity relationship and traditional applications by Santos, Giovanny Carvalho, Martins, Lucas Michelão, Bregadiolli, Bruna Andressa, Moreno, Vitor Fernandes, Silva‐Filho, Luiz Carlos, Silva, Bruno Henrique Sacoman Torquato

“…A virus outbreak challenges the economic, medical, and public health infrastructure worldwide. More than one virus capable of triggering diseases have been…”
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Design, synthesis and in‐vitro evaluation of new furan‐substituted thiadiazolyl hydrazone derivatives as promising antimicrobial agents by Helmy, Mirna T., Sroor, Farid M., Othman, Abdelmageed M., Hassaneen, Hamdi M., Saleh, Fatma M., Teleb, Mohamed A. Mohamed

“…Seventeen new furan‐substituted thiadiazolyl hydrazone derivatives bearing 4‐nitrophenyl moiety were designed, synthesized and tested for their in vitro…”
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