Search Results - "Journal of clinical pathology"

Autopsy in suspected COVID-19 cases by Hanley, Brian, Lucas, Sebastian B, Youd, Esther, Swift, Benjamin, Osborn, Michael

“…The severe acute respiratory syndrome (SARS)-coronavirus-2 (CoV-2) outbreak in Wuhan, China has now spread to many countries across the world including the UK…”
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Histopathological observations in COVID-19: a systematic review by Deshmukh, Vishwajit, Motwani, Rohini, Kumar, Ashutosh, Kumari, Chiman, Raza, Khursheed

“…Coronavirus disease-2019 (COVID-19) has caused a great global threat to public health. The World Health Organization (WHO) has declared COVID-19 disease as a…”
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COVID-19 Autopsies, Oklahoma, USA by Barton, Lisa M, Duval, Eric J, Stroberg, Edana, Ghosh, Subha, Mukhopadhyay, Sanjay

“…Abstract Objectives To report the methods and findings of two complete autopsies of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) positive…”
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PD-L1 by Kythreotou, Anthousa, Siddique, Abdul, Mauri, Francesco A, Bower, Mark, Pinato, David J

“…Programmed death ligand 1 (PD-L1) is the principal ligand of programmed death 1 (PD-1), a coinhibitory receptor that can be constitutively expressed or induced…”
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Cancer diagnostic rates during the 2020 'lockdown', due to COVID-19 pandemic, compared with the 2018-2019: an audit study from cellular pathology by De Vincentiis, Ludovica, Carr, Richard A, Mariani, Maria Paola, Ferrara, Gerardo

“…We performed an audit to evaluate the impact of the COVID-19 pandemic-related delay in the diagnosis of major cancers at a Pathology Unit of a Secondary Care…”
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Placental Pathology in COVID-19 by Shanes, Elisheva D, Mithal, Leena B, Otero, Sebastian, Azad, Hooman A, Miller, Emily S, Goldstein, Jeffery A

“…Abstract Objectives To describe histopathologic findings in the placentas of women with coronavirus disease 2019 (COVID-19) during pregnancy. Methods Pregnant…”
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Gene of the month: the 2019-nCoV/SARS-CoV-2 novel coronavirus spike protein by Pillay, Tahir S

“…The year 2020 has seen a major and sustained outbreak of a novel betacoronavirus (severe acute respiratory syndrome (SARS)-coronavirus (CoV)-2) infection that…”
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Three Emerging Coronaviruses in Two Decades The Story of SARS, MERS, and Now COVID-19 by Guarner, Jeannette

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Assessment of Specimen Pooling to Conserve SARS CoV-2 Testing Resources by Abdalhamid, Baha, Bilder, Christopher R, McCutchen, Emily L, Hinrichs, Steven H, Koepsell, Scott A, Iwen, Peter C

“…Abstract Objectives To establish the optimal parameters for group testing of pooled specimens for the detection of SARS-CoV-2. Methods The most efficient pool…”
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Towards effective diagnostic assays for COVID-19: a review by Venter, Marietjie, Richter, Karin

“…Countries globally are affected by the COVID-19 pandemic, with nearly two million cases and 120 000 deaths occurring within 4 months of the discovery of the…”
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Mechanisms and therapeutic effectiveness of lactobacilli by Di Cerbo, Alessandro, Palmieri, Beniamino, Aponte, Maria, Morales-Medina, Julio Cesar, Iannitti, Tommaso

“…The gut microbiome is not a silent ecosystem but exerts several physiological and immunological functions. For many decades, lactobacilli have been used as an…”
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Gene of the month: TMPRSS2 (transmembrane serine protease 2) by Thunders, Michelle, Delahunt, Brett

“…Transmembrane serine protease 2 is encoded by the gene. The gene is widely conserved and has two isoforms, both being autocatalytically activated from the…”
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Updated UK Recommendations for HER2 assessment in breast cancer by Rakha, Emad A, Pinder, Sarah E, Bartlett, John M S, Ibrahim, Merdol, Starczynski, Jane, Carder, Pauline J, Provenzano, Elena, Hanby, Andrew, Hales, Sally, Lee, Andrew H S, Ellis, Ian O

“…Human epidermal growth factor receptor 2 (HER2) overexpression is present in approximately 15% of early invasive breast cancers, and is an important predictive…”
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Breast cancer stem cell markers CD44, CD24 and ALDH1: expression distribution within intrinsic molecular subtype by Ricardo, Sara, Vieira, André Filipe, Gerhard, Renê, Leitão, Dina, Pinto, Regina, Cameselle-Teijeiro, Jorge F, Milanezi, Fernanda, Schmitt, Fernando, Paredes, Joana

“…The study of CD44/CD24 and ALDH1 expression is the most accurate method to identify cancer stem cells (CSC) from breast cancer populations. However, the…”
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Serum 25(OH)D Level on Hospital Admission Associated With COVID-19 Stage and Mortality by De Smet, Dieter, De Smet, Kristof, Herroelen, Pauline, Gryspeerdt, Stefaan, Martens, Geert A

“…Abstract Objectives Vitamin D deficiency was previously correlated with incidence and severity of coronavirus disease 2019 (COVID-19). We investigated the…”
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COVID-19 autopsy in people who died in community settings: the first series by Youd, Esther, Moore, Luiza

“…Here, we report the pathological findings of nine complete autopsies of individuals who died in community settings in the UK, three of which were positive for…”
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Guidance for laboratories performing molecular pathology for cancer patients by Cree, Ian A, Deans, Zandra, Ligtenberg, Marjolijn J L, Normanno, Nicola, Edsjö, Anders, Rouleau, Etienne, Solé, Francesc, Thunnissen, Erik, Timens, Wim, Schuuring, Ed, Dequeker, Elisabeth, Murray, Samuel, Dietel, Manfred, Groenen, Patricia, Van Krieken, J Han

“…Molecular testing is becoming an important part of the diagnosis of any patient with cancer. The challenge to laboratories is to meet this need, using reliable…”
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Review of Current Advances in Serologic Testing for COVID-19 by Espejo, Andrea P, Akgun, Yamac, Al Mana, Abdulaziz F, Tjendra, Youley, Millan, Nicolas C, Gomez-Fernandez, Carmen, Cray, Carolyn

“…Abstract Objectives To examine and summarize the current literature on serologic methods for the detection of antibodies to severe acute respiratory syndrome…”
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EGFR mutation testing in lung cancer: a review of available methods and their use for analysis of tumour tissue and cytology samples by Ellison, Gillian, Zhu, Guanshan, Moulis, Alexandros, Dearden, Simon, Speake, Georgina, McCormack, Rose

“…Activating mutations in the gene encoding epidermal growth factor receptor (EGFR) can confer sensitivity to EGFR tyrosine kinase inhibitors such as gefitinib…”
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Diagnostic concordance and discordance in digital pathology: a systematic review and meta-analysis by Azam, Ayesha S, Miligy, Islam M, Kimani, Peter K-U, Maqbool, Heeba, Hewitt, Katherine, Rajpoot, Nasir M, Snead, David R J

“…Digital pathology (DP) has the potential to fundamentally change the way that histopathology is practised, by streamlining the workflow, increasing efficiency,…”
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