Search Results - "Journal of cellular physiology"

Macrophage plasticity, polarization, and function in health and disease by Shapouri‐Moghaddam, Abbas, Mohammadian, Saeed, Vazini, Hossein, Taghadosi, Mahdi, Esmaeili, Seyed‐Alireza, Mardani, Fatemeh, Seifi, Bita, Mohammadi, Asadollah, Afshari, Jalil T., Sahebkar, Amirhossein

“…Macrophages are heterogeneous and their phenotype and functions are regulated by the surrounding micro‐environment. Macrophages commonly exist in two distinct…”
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An overview of microRNAs: Biology, functions, therapeutics, and analysis methods by Saliminejad, Kioomars, Khorram Khorshid, Hamid Reza, Soleymani Fard, Shahrzad, Ghaffari, Seyed Hamidollah

“…MicroRNAs (miRNAs) are a class of small noncoding RNAs, which function in posttranscriptional regulation of gene expression. They are powerful regulators of…”
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CD8+ cytotoxic T lymphocytes in cancer immunotherapy: A review by Farhood, Bagher, Najafi, Masoud, Mortezaee, Keywan

“…CD8+ cytotoxic T lymphocytes (CTLs) are preferred immune cells for targeting cancer. During cancer progression, CTLs encounter dysfunction and exhaustion due…”
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A review on coronary artery disease, its risk factors, and therapeutics by Malakar, Arup Kr, Choudhury, Debashree, Halder, Binata, Paul, Prosenjit, Uddin, Arif, Chakraborty, Supriyo

“…Coronary artery disease (CAD) is one of the major cardiovascular diseases affecting the global human population. This disease has been proved to be the major…”
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Insulin resistance: Review of the underlying molecular mechanisms by Yaribeygi, Habib, Farrokhi, Farin Rashid, Butler, Alexandra E., Sahebkar, Amirhossein

“…Most human cells utilize glucose as the primary substrate, cellular uptake requiring insulin. Insulin signaling is therefore critical for these tissues…”
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Pichia pastoris: A highly successful expression system for optimal synthesis of heterologous proteins by Karbalaei, Mohsen, Rezaee, Seyed A., Farsiani, Hadi

“…One of the most important branches of genetic engineering is the expression of recombinant proteins using biological expression systems. Nowadays, different…”
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Cyclooxygenase‐2 in cancer: A review by Hashemi Goradel, Nasser, Najafi, Masoud, Salehi, Eniseh, Farhood, Bagher, Mortezaee, Keywan

“…Cyclooxygenase‐2 (COX‐2) is frequently expressed in many types of cancers exerting a pleiotropic and multifaceted role in genesis or promotion of…”
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Higher infectivity of the SARS‐CoV‐2 new variants is associated with K417N/T, E484K, and N501Y mutants: An insight from structural data by Khan, Abbas, Zia, Tauqir, Suleman, Muhammad, Khan, Taimoor, Ali, Syed Shujait, Abbasi, Aamir Ali, Mohammad, Anwar, Wei, Dong‐Qing

“…The evolution of the SARS‐CoV‐2 new variants reported to be 70% more contagious than the earlier one is now spreading fast worldwide. There is an instant need…”
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Cancer stem cells (CSCs) in cancer progression and therapy by Najafi, Masoud, Farhood, Bagher, Mortezaee, Keywan

“…Cancer stem cells (CSCs) are self‐renewable cell types that are identified in most types of liquid and solid cancers and contributed to tumor onset, expansion,…”
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Circular RNA in cardiovascular disease by Altesha, M‐Ashraf, Ni, Tiffany, Khan, Afaan, Liu, Kexiang, Zheng, Xiufen

“…Circular RNA (circRNA) are endogenous transcripts that display differential expression across species, developmental stages, and pathologies. Their lack of…”
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Nanoparticles and cancer therapy: Perspectives for application of nanoparticles in the treatment of cancers by Aghebati‐Maleki, Ali, Dolati, Sanam, Ahmadi, Majid, Baghbanzhadeh, Amir, Asadi, Milad, Fotouhi, Ali, Yousefi, Mehdi, Aghebati‐Maleki, Leili

“…Rapid growth in nanotechnology toward the development of nanomedicine agents holds massive promise to improve therapeutic approaches against cancer…”
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Nrf2–ARE signaling in cellular protection: Mechanism of action and the regulatory mechanisms by Shaw, Pallab, Chattopadhyay, Ansuman

“…Oxidative stress is the increase in cellular oxidant concentration in comparison to antioxidant titer. Toxic insults and many other diseased conditions are…”
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Oxidative stress in oocyte aging and female reproduction by Wang, Ling, Tang, Jinhua, Wang, Lei, Tan, Feng, Song, Huibin, Zhou, Jiawei, Li, Fenge

“…In a healthy body, reactive oxygen species (ROS) and antioxidants remain balanced. When the balance is broken toward an overabundance of ROS, oxidative stress…”
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PD‐1/PD‐L1 pathway: Basic biology and role in cancer immunotherapy by Salmaninejad, Arash, Valilou, Saeed Farajzadeh, Shabgah, Arezoo Gowhari, Aslani, Saeed, Alimardani, Malihe, Pasdar, Alireza, Sahebkar, Amirhossein

“…Over the course of past few years, cancer immunotherapy has been accompanied with promising results. However, preliminary investigations with respect to…”
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Strategies toward rheumatoid arthritis therapy; the old and the new by Abbasi, Mojtaba, Mousavi, Mohammad Javad, Jamalzehi, Sirous, Alimohammadi, Reza, Bezvan, Maryam Hasanzadeh, Mohammadi, Hamed, Aslani, Saeed

“…Currently, medications used to treat rheumatoid arthritis (RA) are glucocorticoids (GCs) and nonsteroidal anti‐inflammatory drugs (NSAIDs), predominantly used…”
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PD‐1/PD‐L1 immune checkpoint: Potential target for cancer therapy by Dermani, Fatemeh K., Samadi, Pouria, Rahmani, Golebagh, Kohlan, Alisa K., Najafi, Rezvan

“…Recent studies show that cancer cells are sometimes able to evade the host immunity in the tumor microenvironment. Cancer cells can express high levels of…”
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Mechanisms of apoptosis modulation by curcumin: Implications for cancer therapy by Mortezaee, Keywan, Salehi, Ensieh, Mirtavoos‐mahyari, Hanifeh, Motevaseli, Elahe, Najafi, Masoud, Farhood, Bagher, Rosengren, Rhonda J., Sahebkar, Amirhossein

“…Cancer incidences are growing and cause millions of deaths worldwide. Cancer therapy is one of the most important challenges in medicine. Improving therapeutic…”
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Epithelial–mesenchymal transition (EMT): A biological process in the development, stem cell differentiation, and tumorigenesis by Chen, Tong, You, Yanan, Jiang, Hua, Wang, Zack Z.

“…The lineage transition between epithelium and mesenchyme is a process known as epithelial–mesenchymal transition (EMT), by which polarized epithelial cells…”
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NLRP3 inflammasome: Its regulation and involvement in atherosclerosis by Hoseini, Zahra, Sepahvand, Fatemeh, Rashidi, Bahman, Sahebkar, Amirhossein, Masoudifar, Aria, Mirzaei, Hamed

“…Inflammasomes are intracellular complexes involved in the innate immunity that convert proIL‐1β and proIL‐18 to mature forms and initiate pyroptosis via…”
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Breast cancer diagnosis: Imaging techniques and biochemical markers by Jafari, Seyed Hamed, Saadatpour, Zahra, Salmaninejad, Arash, Momeni, Fatemeh, Mokhtari, Mojgan, Nahand, Javid Sadri, Rahmati, Majid, Mirzaei, Hamed, Kianmehr, Mojtaba

“…Breast cancer is a complex disease which is found as the second cause of cancer‐associated death among women. Accumulating of evidence indicated that various…”
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