Search Results - "Journal of bone and mineral research (Print)"

Vitamin D and Skin Physiology: A D‐Lightful Story by Holick, Michael F, Chen, Tai C, Lu, Zhiren, Sauter, Edward

“…Throughout evolution, exposure to sunlight and the photosynthesis of vitamin D3 in the skin has been critically important for the evolution of land…”
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Vitamin D Toxicity, Policy, and Science by Vieth, Reinhold

“…The serum 25‐hydroxyvitamin D [25(OH)D] concentration that is the threshold for vitamin D toxicity has not been established. Hypercalcemia is the hazard…”
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Patients with Prior Fractures Have an Increased Risk of Future Fractures: A Summary of the Literature and Statistical Synthesis by Klotzbuecher, Carolyn M., Ross, Philip D., Landsman, Pamela B., Abbott, Thomas A., Berger, Marc

“…Numerous studies have reported increased risks of hip, spine, and other fractures among people who had previous clinically diagnosed fractures, or who have…”
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Adverse Outcomes of Osteoporotic Fractures in the General Population by Melton, L Joseph

“…Osteoporotic fractures exact a terrible toll on the population with respect to morbidity and cost, and to a lesser extent mortality, which will increase…”
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Vitamin D Receptor: Key Roles in Bone Mineral Pathophysiology, Molecular Mechanism of Action, and Novel Nutritional Ligands by Jurutka, Peter W, Bartik, Leonid, Whitfield, G Kerr, Mathern, Douglas R, Barthel, Thomas K, Gurevich, Miriam, Hsieh, Jui‐Cheng, Kaczmarska, Magdalena, Haussler, Carol A, Haussler, Mark R

“…The vitamin D hormone, 1,25‐dihydroxyvitamin D3 [1,25(OH)2D3], binds with high affinity to the nuclear vitamin D receptor (VDR), which recruits its retinoid X…”
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Osteosarcoma in Paget's Disease of Bone by Hansen, Marc F, Seton, Margaret, Merchant, Anand

“…Paget's disease of bone (PDB) is a focal disorder of bone metabolism first described by Sir James Paget in 1876. It is presumed benign in nature and mediated…”
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Vitamin D Deficiency and Primary Hyperparathyroidism by Silverberg, Shonni J

“…Temporally associated with the improvement in vitamin D nutrition in many Western countries in the mid‐20th century, there was a change in many characteristics…”
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Sequestosome 1: Mutation Frequencies, Haplotypes, and Phenotypes in Familial Paget's Disease of Bone by Morissette, Jean, Laurin, Nancy, Brown, Jacques P

“…Mutations of the SQSTM1/p62 gene are commonly observed in PDB. Screening an updated sample from Quebec and using previously published data from other…”
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Risk Factors for Longitudinal Bone Loss in Elderly Men and Women: The Framingham Osteoporosis Study by Hannan, Marian T., Felson, David T., Dawson‐Hughes, Bess, Tucker, Katherine L., Cupples, L. Adrienne, Wilson, Peter W. F., Kiel, Douglas P.

“…Few studies have evaluated risk factors for bone loss in elderly women and men. Thus, we examined risk factors for 4‐year longitudinal change in bone mineral…”
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Suppressed Bone Turnover by Bisphosphonates Increases Microdamage Accumulation and Reduces Some Biomechanical Properties in Dog Rib by Mashiba, Tasuku, Hirano, Toru, Turner, Charles H., Forwood, Mark R., Johnston, C. Conrad, Burr, David B.

“…It has been hypothesized that suppression of bone remodeling allows microdamage to accumulate, leading to increased bone fragility. This study evaluated the…”
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Medical Therapy in Adults With Fibrous Dysplasia of Bone by Chapurlat, Roland D

“…In open studies, bisphosphonate therapy (pamidronate, alendronate) reduced bone pain associated with fibrous dysplasia of bone and was associated to some…”
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Update on the Epidemiology of Paget's Disease of Bone by Cooper, Cyrus, Harvey, Nicholas C, Dennison, Elaine M, van Staa, Tjeerd P

“…Paget's disease of bone (PDB) is characterized by rapid bone remodeling and the formation of bone that is structurally abnormal. Recent studies have confirmed…”
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Gsα Mutations in Fibrous Dysplasia and McCune‐Albright Syndrome by Weinstein, Lee S

“…Fibrous dysplasia (FD) is a focal bone lesion composed of immature mesenchymal osteoblastic precursor cells. Some FD patients also have hyperpigmented skin…”
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Isolation and Characterization of MC3T3‐E1 Preosteoblast Subclones with Distinct In Vitro and In Vivo Differentiation/Mineralization Potential by Wang, Dian, Christensen, Kurt, Chawla, Kanwal, Xiao, Guozhi, Krebsbach, Paul H., Franceschi, Renny T.

“…A series of subclonal cell lines with high or low differentiation/mineralization potential after growth in the presence of ascorbic acid (AA) were derived from…”
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Epidemiology of primary hyperparathyroidism in Europe by ADAMI, Silvano, MARCOCCI, Claudio, GATTI, Davide

“…Primary hyperparathyroidism (PHPT) is one of the most common endocrine diseases. Its clinical presentation has dramatically changed in the last 40 years, and…”
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Vitamin D Requirement During Pregnancy and Lactation by Hollis, Bruce W

“…The current recommended dietary requirement for vitamin D intake (200 IU/d) during pregnancy and lactation is based on little, if any, scientific evidence, and…”
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Fibrous Dysplasia as a Stem Cell Disease by Riminucci, Mara, Saggio, Isabella, Gehron Robey, Pamela, Bianco, Paolo

“…At a time when significant attention is devoted worldwide to stem cells as a potential tool for curing incurable diseases, fibrous dysplasia of bone (FD)…”
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Vitamin D Insufficiency/Deficiency in Gastrointestinal Disorders by Bikle, Daniel D

“…Vitamin D and calcium are critical for skeletal health. Their absorption from the intestine is negatively impacted by a number of gastrointestinal diseases and…”
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Targets of Vitamin D Receptor Signaling in the Mammary Gland by Welsh, JoEllen

“…Since the discovery of the vitamin D receptor (VDR) in mammary cells, the role of the vitamin D signaling pathway in normal glandular function and in breast…”
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Molecular Actions of 1,25‐Dihydroxyvitamin D3 on Genes Involved in Calcium Homeostasis by Pike, J Wesley, Zella, Lee A, Meyer, Mark B, Fretz, Jackie A, Kim, Sungtae

“…1,25‐Dihydroxyvitamin D3 [1,25(OH)2D3] functions in vertebrate organisms as a primary regulator of calcium and phosphorus homeostasis, an activity that is…”
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