Search Results - "Journal of biomedical science"

Development of therapeutic antibodies for the treatment of diseases by Lu, Ruei-Min, Hwang, Yu-Chyi, Liu, I-Ju, Lee, Chi-Chiu, Tsai, Han-Zen, Li, Hsin-Jung, Wu, Han-Chung

“…It has been more than three decades since the first monoclonal antibody was approved by the United States Food and Drug Administration (US FDA) in 1986, and…”
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Tumor-associated macrophages: an accomplice in solid tumor progression by Chen, Yibing, Song, Yucen, Du, Wei, Gong, Longlong, Chang, Haocai, Zou, Zhengzhi

“…In many solid tumor types, tumor-associated macrophages (TAMs) are important components of the tumor microenvironment (TME). Moreover, TAMs infiltration is…”
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Clinical trials of new drugs for Alzheimer disease by Huang, Li-Kai, Chao, Shu-Ping, Hu, Chaur-Jong

“…Alzheimer disease (AD) accounts for 60-70% of dementia cases. Given the seriousness of the disease and continual increase in patient numbers, developing…”
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Coronavirus vaccine development: from SARS and MERS to COVID-19 by Li, Yen-Der, Chi, Wei-Yu, Su, Jun-Han, Ferrall, Louise, Hung, Chien-Fu, Wu, T-C

“…Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is a new type of coronavirus that causes the Coronavirus Disease 2019 (COVID-19), which has been…”
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Alzheimer's disease: risk factors and potentially protective measures by Silva, Marcos Vinícius Ferreira, Loures, Cristina de Mello Gomide, Alves, Luan Carlos Vieira, de Souza, Leonardo Cruz, Borges, Karina Braga Gomes, Carvalho, Maria das Graças

“…Alzheimer's disease (AD) is the most common type of dementia and typically manifests through a progressive loss of episodic memory and cognitive function,…”
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Cancer stem cells as key drivers of tumour progression by Ayob, Ain Zubaidah, Ramasamy, Thamil Selvee

“…Cancer stem cells (CSCs) are subpopulations of cancer cells sharing similar characteristics as normal stem or progenitor cells such as self-renewal ability and…”
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Inhibition of H1N1 influenza virus infection by zinc oxide nanoparticles: another emerging application of nanomedicine by Ghaffari, Hadi, Tavakoli, Ahmad, Moradi, Abdolvahab, Tabarraei, Alijan, Bokharaei-Salim, Farah, Zahmatkeshan, Masoumeh, Farahmand, Mohammad, Javanmard, Davod, Kiani, Seyed Jalal, Esghaei, Maryam, Pirhajati-Mahabadi, Vahid, Monavari, Seyed Hamidreza, Ataei-Pirkooh, Angila

“…Currently available anti-influenza drugs are often associated with limitations such as toxicity and the appearance of drug-resistant strains. Therefore, there…”
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The emerging roles and functions of circular RNAs and their generation by Yu, Chun-Ying, Kuo, Hung-Chih

“…Circular RNAs (circRNAs) are closed long non-coding RNAs, in which the 5' and 3' termini are covalently linked by back-splicing of exons from a single…”
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Insights to SARS-CoV-2 life cycle, pathophysiology, and rationalized treatments that target COVID-19 clinical complications by Trougakos, Ioannis P, Stamatelopoulos, Kimon, Terpos, Evangelos, Tsitsilonis, Ourania E, Aivalioti, Evmorfia, Paraskevis, Dimitrios, Kastritis, Efstathios, Pavlakis, George N, Dimopoulos, Meletios A

“…Gaining further insights into SARS-CoV-2 routes of infection and the underlying pathobiology of COVID-19 will support the design of rational treatments…”
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Molecular mechanisms of cisplatin-induced nephrotoxicity: a balance on the knife edge between renoprotection and tumor toxicity by Volarevic, Vladislav, Djokovic, Bojana, Jankovic, Marina Gazdic, Harrell, C Randall, Fellabaum, Crissy, Djonov, Valentin, Arsenijevic, Nebojsa

“…Cisplatin (cis-diamminedichloroplatinum II, CDDP) is one of the most effective chemotherapeutic agents. However, its clinical use is limited due to the severe…”
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Tumor microenvironment: barrier or opportunity towards effective cancer therapy by Tiwari, Aadhya, Trivedi, Rakesh, Lin, Shiaw-Yih

“…Abstract Tumor microenvironment (TME) is a specialized ecosystem of host components, designed by tumor cells for successful development and metastasis of…”
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Cancer immunotherapies targeting the PD-1 signaling pathway by Iwai, Yoshiko, Hamanishi, Junzo, Chamoto, Kenji, Honjo, Tasuku

“…Immunotherapy has recently emerged as the fourth pillar of cancer treatment, joining surgery, radiation, and chemotherapy. While early immunotherapies focused…”
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Current and novel polymeric biomaterials for neural tissue engineering by Boni, Rossana, Ali, Azam, Shavandi, Amin, Clarkson, Andrew N

“…The nervous system is a crucial component of the body and damages to this system, either by of injury or disease, can result in serious or potentially lethal…”
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Probiotics, prebiotics and amelioration of diseases by Tsai, Yu-Ling, Lin, Tzu-Lung, Chang, Chih-Jung, Wu, Tsung-Ru, Lai, Wei-Fan, Lu, Chia-Chen, Lai, Hsin-Chih

“…Dysbiosis of gut microbiota is closely related to occurrence of many important chronic inflammations-related diseases. So far the traditionally prescribed…”
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Monoclonal antibodies for COVID-19 therapy and SARS-CoV-2 detection by Hwang, Yu-Chyi, Lu, Ruei-Min, Su, Shih-Chieh, Chiang, Pao-Yin, Ko, Shih-Han, Ke, Feng-Yi, Liang, Kang-Hao, Hsieh, Tzung-Yang, Wu, Han-Chung

“…The coronavirus disease 2019 (COVID-19) pandemic is an exceptional public health crisis that demands the timely creation of new therapeutics and viral…”
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Microbiota dysbiosis and barrier dysfunction in inflammatory bowel disease and colorectal cancers: exploring a common ground hypothesis by Yu, Linda Chia-Hui

“…Inflammatory bowel disease (IBD) is a multifactorial disease which arises as a result of the interaction of genetic, environmental, barrier and microbial…”
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Evaluation of the use of therapeutic peptides for cancer treatment by Marqus, Susan, Pirogova, Elena, Piva, Terrence J

“…Cancer along with cardiovascular disease are the main causes of death in the industrialised countries around the World. Conventional cancer treatments are…”
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Imaging extracellular vesicles: current and emerging methods by Chuo, Steven Ting-Yu, Chien, Jasper Che-Yung, Lai, Charles Pin-Kuang

“…Extracellular vesicles (EVs) are lipid bilayer-enclosed nanoparticles released by cells. They range from 30 nm to several micrometers in diameter, and ferry…”
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Drug candidates in clinical trials for Alzheimer's disease by Hung, Shih-Ya, Fu, Wen-Mei

“…Alzheimer's disease (AD) is a major form of senile dementia, characterized by progressive memory and neuronal loss combined with cognitive impairment. AD is…”
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COVID-19 vaccine update: vaccine effectiveness, SARS-CoV-2 variants, boosters, adverse effects, and immune correlates of protection by Chi, Wei-Yu, Li, Yen-Der, Huang, Hsin-Che, Chan, Timothy En Haw, Chow, Sih-Yao, Su, Jun-Han, Ferrall, Louise, Hung, Chien-Fu, Wu, T-C

“…Coronavirus Disease 2019 (COVID-19) has been the most severe public health challenge in this century. Two years after its emergence, the rapid development and…”
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