Search Results - "Journal of Pharmacology and Pharmacotherapeutics"

How to calculate sample size in animal studies? by Charan, Jaykaran, Kantharia, N D

“…Calculation of sample size is one of the important component of design of any research including animal studies. If a researcher select less number of animals…”
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L-asparaginase in the treatment of patients with acute lymphoblastic leukemia by Egler, Rachel, Ahuja, Sanjay, Matloub, Yousif

“…Acute lymphoblastic leukemia (ALL) is a hematologic malignancy that predominantly occurs in children between 2 and 10 years of age. L-asparaginase is an…”
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Clinical and economic burden of adverse drug reactions by Sultana, Janet, Cutroneo, Paola, Trifirò, Gianluca

“…Adverse drug reactions (ADRs) are unwanted drug effects that have considerable economic as well as clinical costs as they often lead to hospital admission,…”
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Blood sample collection in small laboratory animals by Parasuraman, S, Raveendran, R, Kesavan, R

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Vitamin D: The "sunshine" vitamin by Nair, Rathish, Maseeh, Arun

“…Vitamin D insufficiency affects almost 50% of the population worldwide. An estimated 1 billion people worldwide, across all ethnicities and age groups, have a…”
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Improving bioscience research reporting: The ARRIVE guidelines for reporting animal research by Kilkenny, Carol, Browne, William J, Cuthill, Innes C, Emerson, Michael, Altman, Douglas G

“…[...] a wealth of evidence shows that across many areas, the reporting of biomedical research is often inadequate, leading to the view that even if the science…”
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Toxicological screening by Parasuraman, S

“…Toxicity testing of new compounds is essential for drug development process. The preclinical toxicity testing on various biological systems reveals the…”
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Sofosbuvir: A novel treatment option for chronic hepatitis C infection by Bhatia, Harmeet Kaur, Singh, Harmanjit, Grewal, Nipunjot, Natt, Navreet Kaur

“…Hepatitis C currently infects more than 170 million people around the world, leading to significant morbidity and mortality. The current standard of care for…”
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Switch over from intravenous to oral therapy: A concise overview by Cyriac, Jissa Maria, James, Emmanuel

“…Majority of the patients admitted to a hospital with severe infections are initially started with intravenous medications. Short intravenous course of therapy…”
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Critical appraisal skills programme by Singh, Jatinder

“…The internet has redefined and simplified search capabilities of individuals by ensuring the availability of various databases of systematic reviews,…”
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Corticosteroid-related central nervous system side effects by Ciriaco, Miriam, Ventrice, Pasquale, Russo, Gaetano, Scicchitano, Maria, Mazzitello, Giovanni, Scicchitano, Francesca, Russo, Emilio

“…Corticosteroids have been used since the 50s as anti-inflammatory and immunosuppressive drugs for the treatment of several pathologies such as asthma, allergy,…”
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International conference on harmonization of technical requirements for registration of pharmaceuticals for human use by Singh, Jatinder

“…Following famous cases such as the Nazi's experiments on concentration camp prisoners in WWII and the Tuskegee syphilis study (1932-1972), agreements for the…”
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Vitamin D for prevention of respiratory tract infections: A systematic review and meta-analysis by Charan, Jaykaran, Goyal, Jagdish P, Saxena, Deepak, Yadav, Preeti

“…To explore the effect of vitamin D supplementation in prevention of respiratory tract infections on the basis of published clinical trials. Clinical trials…”
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A Review on Pharmacological Advancement of Ellagic Acid by Golmei, Pougang, Kasna, Sweta, Roy, Kumar Probin, Kumar, Sachin

“…Background In recent years, ellagic acid has emerged as a focal point in pharmacological research, showcasing promising developments and potential therapeutic…”
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A Review on the Poisonous Plant Cleistanthus collinus by Priyadharsini, Raman P., Parasuraman, Subramani, Puli, Sagar, Raveendran, Ramasamy

“…Cleistanthus collinus is a toxic plant belonging to the Euphorbiaceae family, and all parts of the plant are poisonous. It is used as suicidal, homicidal,…”
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Anti-inflammatory Property of Ethanolic Extract of Cleome spinosa Leaves in an in vivo Model of Delayed-type Hypersensitivity by Roy, Torisa, Mazumder, Tamal, Sharma, Priyanka, Roy, Tamali, Nag, Tapas Chandra, Bindu, Samik, Dasgupta, Subir Chandra, Yasmin, Hadida

“…Objectives Delayed-type hypersensitivity (DTH) reactions represent a clinically important class of immune responses that have wide-ranging implications in…”
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Adipokine Modulation in Endometrial Hyperplasia by Polyunsaturated Fatty Acids by Supriya, Athuru, Kiran, Ammu V. V. V. Ravi, Krishnamurthy, Praveen Thaggikuppe

“…Background Obesity is associated with a higher prevalence of endometrial hyperplasia, thereby increasing the risk of endometrial and ovarian cancers. The…”
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Neurotoxicity by Hypoxia an Intermediate Between Alpha-synuclein and Mitochondrial Dysfunction in Parkinson’s Disease by Chand, Jagdish, Fanai, Hannah Lalengzuali, Antony, A. S., Subramanian, Gomathy

“…This review article explores the relationship between alpha-synuclein and mitochondrial dysfunction in Parkinson’s disease (PD), focusing on the role of…”
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An Overview of Indian Marine Seaweeds and their Medicinal Applications by R., Kavya, Ananthy, Vimala, Salwe, Kartik Janardan, Manimekalai, K., Komarasamy, Boopathi, Deva, Reka

“…Background Seaweeds are macroalgae containing bioactive compounds that have positively impacted the biomedical field due to polysaccharides, sterols and…”
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A Review on the Pharmacological Importance of PDE5 and Its Inhibition to Manage Biomedical Conditions by Saikia, Queen, Hazarika, Ajit, Mishra, Ritu

“…Phosphodiesterase type 5 (PDE5) is a cyclic GMP (cGMP) specific protein. It hydrolyzes the phosphodiesterase linkage and catalyzes the conversion of cGMP to 5’…”
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