Search Results - "Journal of Nuclear Medicine"

Introduction to Radiomics by Mayerhoefer, Marius E, Materka, Andrzej, Langs, Georg, Häggström, Ida, Szczypiński, Piotr, Gibbs, Peter, Cook, Gary

“…Radiomics is a rapidly evolving field of research concerned with the extraction of quantitative metrics-the so-called radiomic features-within medical images…”
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Development of Quinoline-Based Theranostic Ligands for the Targeting of Fibroblast Activation Protein by Lindner, Thomas, Loktev, Anastasia, Altmann, Annette, Giesel, Frederik, Kratochwil, Clemens, Debus, Jürgen, Jäger, Dirk, Mier, Walter, Haberkorn, Uwe

“…Fibroblast activation protein (FAP) is overexpressed in cancer-associated fibroblasts and is involved in a variety of tumor-promoting activities such as matrix…”
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A Tumor-Imaging Method Targeting Cancer-Associated Fibroblasts by Loktev, Anastasia, Lindner, Thomas, Mier, Walter, Debus, Jürgen, Altmann, Annette, Jäger, Dirk, Giesel, Frederik, Kratochwil, Clemens, Barthe, Philippe, Roumestand, Christian, Haberkorn, Uwe

“…The tumor stroma, which accounts for a large part of the tumor mass, represents an attractive target for the delivery of diagnostic and therapeutic compounds…”
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Total-Body PET: Maximizing Sensitivity to Create New Opportunities for Clinical Research and Patient Care by Cherry, Simon R, Jones, Terry, Karp, Joel S, Qi, Jinyi, Moses, William W, Badawi, Ramsey D

“…PET is widely considered the most sensitive technique available for noninvasively studying physiology, metabolism, and molecular pathways in the living human…”
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Development of Fibroblast Activation Protein-Targeted Radiotracers with Improved Tumor Retention by Loktev, Anastasia, Lindner, Thomas, Burger, Eva-Maria, Altmann, Annette, Giesel, Frederik, Kratochwil, Clemens, Debus, Jürgen, Marmé, Frederik, Jäger, Dirk, Mier, Walter, Haberkorn, Uwe

“…Cancer-associated fibroblasts constitute a vital subpopulation of the tumor stroma and are present in more than 90% of epithelial carcinomas. The…”
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Prostate Cancer Molecular Imaging Standardized Evaluation (PROMISE): Proposed miTNM Classification for the Interpretation of PSMA-Ligand PET/CT by Eiber, Matthias, Herrmann, Ken, Calais, Jeremie, Hadaschik, Boris, Giesel, Frederik L, Hartenbach, Markus, Hope, Thomas, Reiter, Robert, Maurer, Tobias, Weber, Wolfgang A, Fendler, Wolfgang P

“…Prostate-specific membrane antigen (PSMA)-ligand PET imaging provides unprecedented accuracy for whole-body staging of prostate cancer. As PSMA-ligand PET/CT…”
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Performance Characteristics of the Biograph Vision Quadra PET/CT System with a Long Axial Field of View Using the NEMA NU 2-2018 Standard by Prenosil, George A, Sari, Hasan, Fürstner, Markus, Afshar-Oromieh, Ali, Shi, Kuangyu, Rominger, Axel, Hentschel, Michael

“…Our purpose was to evaluate the performance of the Biograph Vision Quadra PET/CT system. This new system is based on the Biograph Vision 600, using the same…”
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The Latest Developments in Imaging of Fibroblast Activation Protein by Altmann, Annette, Haberkorn, Uwe, Siveke, Jens

“…Fibroblast activation protein (FAP), a membrane-anchored peptidase, is highly expressed in cancer-associated fibroblasts in more than 90% of epithelial tumors…”
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A Postreconstruction Harmonization Method for Multicenter Radiomic Studies in PET by Orlhac, Fanny, Boughdad, Sarah, Philippe, Cathy, Stalla-Bourdillon, Hugo, Nioche, Christophe, Champion, Laurence, Soussan, Michaël, Frouin, Frédérique, Frouin, Vincent, Buvat, Irène

“…Several reports have shown that radiomic features are affected by acquisition and reconstruction parameters, thus hampering multicenter studies. We propose a…”
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Future of Theranostics: An Outlook on Precision Oncology in Nuclear Medicine by Langbein, Thomas, Weber, Wolfgang A, Eiber, Matthias

“…Molecular alterations in malignant disease result in the expression or upregulations of various targets that can be used for imaging and treatment with…”
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Total-Body Dynamic Reconstruction and Parametric Imaging on the uEXPLORER by Zhang, Xuezhu, Xie, Zhaoheng, Berg, Eric, Judenhofer, Martin S, Liu, Weiping, Xu, Tianyi, Ding, Yu, Lv, Yang, Dong, Yun, Deng, Zilin, Tang, Songsong, Shi, Hongcheng, Hu, Pengcheng, Chen, Shuguang, Bao, Jun, Li, Hongdi, Zhou, Jian, Wang, Guobao, Cherry, Simon R, Badawi, Ramsey D, Qi, Jinyi

“…The world's first 194-cm-long total-body PET/CT scanner (uEXPLORER) has been built by the EXPLORER Consortium to offer a transformative platform for human…”
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Impact of 68Ga-FAPI PET/CT Imaging on the Therapeutic Management of Primary and Recurrent Pancreatic Ductal Adenocarcinomas by Röhrich, Manuel, Naumann, Patrick, Giesel, Frederik L, Choyke, Peter L, Staudinger, Fabian, Wefers, Annika, Liew, Dawn P, Kratochwil, Clemens, Rathke, Hendrik, Liermann, Jakob, Herfarth, Klaus, Jäger, Dirk, Debus, Jürgen, Haberkorn, Uwe, Lang, Matthias, Koerber, Stefan A

“…Pancreatic ductal carcinoma (PDAC) is a highly lethal cancer, and early detection and accurate staging are critical to prolonging survival. PDAC typically has…”
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First Human Imaging Studies with the EXPLORER Total-Body PET Scanner by Badawi, Ramsey D, Shi, Hongcheng, Hu, Pengcheng, Chen, Shuguang, Xu, Tianyi, Price, Patricia M, Ding, Yu, Spencer, Benjamin A, Nardo, Lorenzo, Liu, Weiping, Bao, Jun, Jones, Terry, Li, Hongdi, Cherry, Simon R

“…Within the EXPLORER Consortium, the construction of the world's first total-body PET/CT scanner has recently been completed. The 194-cm axial field of view of…”
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Incidental Findings Suggestive of COVID-19 in Asymptomatic Patients Undergoing Nuclear Medicine Procedures in a High-Prevalence Region by Albano, Domenico, Bertagna, Francesco, Bertoli, Mattia, Bosio, Giovanni, Lucchini, Silvia, Motta, Federica, Panarotto, Maria Beatrice, Peli, Alessia, Camoni, Luca, Bengel, Frank M, Giubbini, Raffaele

“…Infection with the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) may remain asymptomatic, leading to under-recognition of the related…”
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Metaanalysis of 68Ga-PSMA-11 PET Accuracy for the Detection of Prostate Cancer Validated by Histopathology by Hope, Thomas A, Goodman, Jeremy Z, Allen, Isabel E, Calais, Jeremie, Fendler, Wolfgang P, Carroll, Peter R

“…68Ga-PSMA-11 PET is used to stage patients with prostate cancer. We performed an updated metaanalysis that separates imaging at the time of diagnosis and at…”
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Clinical Diagnosis and Management of Breast Cancer by McDonald, Elizabeth S, Clark, Amy S, Tchou, Julia, Zhang, Paul, Freedman, Gary M

“…The diagnosis and management of breast cancer are undergoing a paradigm shift from a one-size-fits-all approach to an era of personalized medicine…”
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Novel Framework for Treatment Response Evaluation Using PSMA PET/CT in Patients with Metastatic Castration-Resistant Prostate Cancer (RECIP 1.0): An International Multicenter Study by Gafita, Andrei, Rauscher, Isabel, Weber, Manuel, Hadaschik, Boris, Wang, Hui, Armstrong, Wesley R, Tauber, Robert, Grogan, Tristan R, Czernin, Johannes, Rettig, Matthew B, Herrmann, Ken, Calais, Jeremie, Weber, Wolfgang A, Benz, Matthias R, Fendler, Wolfgang P, Eiber, Matthias

“…Our objective was to develop version 1.0 of a novel framework for response evaluation criteria in prostate-specific membrane antigen (PSMA) PET/CT (RECIP) and…”
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Performance Evaluation of the uEXPLORER Total-Body PET/CT Scanner Based on NEMA NU 2-2018 with Additional Tests to Characterize PET Scanners with a Long Axial Field of View by Spencer, Benjamin A, Berg, Eric, Schmall, Jeffrey P, Omidvari, Negar, Leung, Edwin K, Abdelhafez, Yasser G, Tang, Songsong, Deng, Zilin, Dong, Yun, Lv, Yang, Bao, Jun, Liu, Weiping, Li, Hongdi, Jones, Terry, Badawi, Ramsey D, Cherry, Simon R

“…The world's first total-body PET scanner with an axial field of view (AFOV) of 194 cm is now in clinical and research use at our institution. The uEXPLORER…”
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Performance Characteristics of the Digital Biograph Vision PET/CT System by van Sluis, Joyce, de Jong, Johan, Schaar, Jenny, Noordzij, Walter, van Snick, Paul, Dierckx, Rudi, Borra, Ronald, Willemsen, Antoon, Boellaard, Ronald

“…This study evaluated the performance of the Biograph Vision digital PET/CT system according to the NEMA NU 2-2012 standard (published by the National…”
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Appropriate Use Criteria for Somatostatin Receptor PET Imaging in Neuroendocrine Tumors by Hope, Thomas A, Bergsland, Emily K, Bozkurt, Murat Fani, Graham, Michael, Heaney, Anthony P, Herrmann, Ken, Howe, James R, Kulke, Matthew H, Kunz, Pamela L, Mailman, Josh, May, Lawrence, Metz, David C, Millo, Corina, O'Dorisio, Sue, Reidy-Lagunes, Diane L, Soulen, Michael C, Strosberg, Jonathan R

“…Somatostatin receptor (SSTR) PET has demonstrated a significant improvement over conventional imaging (CI) in patients with neuroendocrine tumors (NETs). SSTR…”
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