Search Results - "Journal of Neural Transmission"

Epidemiology of Parkinson’s disease by Tysnes, Ole-Bjørn, Storstein, Anette

“…Parkinson’s disease (PD) affects 1–2 per 1000 of the population at any time. PD prevalence is increasing with age and PD affects 1% of the population above…”
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Animal models of major depression: drawbacks and challenges by Planchez, Barbara, Surget, Alexandre, Belzung, Catherine

“…Major depression is a leading contributor to the global burden of disease. This situation is mainly related to the chronicity and/or recurrence of the…”
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Challenges of neuropathic pain: focus on diabetic neuropathy by Rosenberger, Daniela C., Blechschmidt, Vivian, Timmerman, Hans, Wolff, André, Treede, Rolf-Detlef

“…Neuropathic pain is a frequent condition caused by a lesion or disease of the central or peripheral somatosensory nervous system. A frequent cause of…”
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Glutamate as a neurotransmitter in the healthy brain by Zhou, Y., Danbolt, N. C.

“…Glutamate is the most abundant free amino acid in the brain and is at the crossroad between multiple metabolic pathways. Considering this, it was a surprise to…”
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Sleep and pain: recent insights, mechanisms, and future directions in the investigation of this relationship by Herrero Babiloni, Alberto, De Koninck, Beatrice P., Beetz, Gabrielle, De Beaumont, Louis, Martel, Marc O., Lavigne, Gilles J.

“…Sleep disturbances and chronic pain are considered public health concerns. They are frequently associated, and the direction of its relationship and possible…”
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Dementia with Lewy bodies and Parkinson’s disease-dementia: current concepts and controversies by Jellinger, Kurt A.

“…Dementia with Lewy bodies (DLB) and Parkinson’s disease-dementia (PDD), although sharing many clinical, neurochemical and morphological features, according to…”
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The IL-1β phenomena in neuroinflammatory diseases by Mendiola, Andrew S., Cardona, Astrid E.

“…It is becoming increasingly clear that neuroinflammation has a causal role in the pathogenesis of central nervous system (CNS)-related diseases, and therefore…”
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Magnetic resonance imaging for the diagnosis of Parkinson’s disease by Heim, Beatrice, Krismer, Florian, De Marzi, Roberto, Seppi, Klaus

“…The differential diagnosis of parkinsonian syndromes is considered one of the most challenging in neurology and error rates in the clinical diagnosis can be…”
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Parkinson’s: a syndrome rather than a disease? by Titova, Nataliya, Padmakumar, C., Lewis, Simon J. G., Chaudhuri, K. Ray

“…Emerging concepts suggest that a multitude of pathology ranging from misfolding of alpha-synuclein to neuroinflammation, mitochondrial dysfunction, and…”
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Modelling the neurodevelopmental pathogenesis in neuropsychiatric disorders. Bioactive kynurenines and their analogues as neuroprotective agents—in celebration of 80th birthday of Professor Peter Riederer by Tanaka, Masaru, Spekker, Eleonóra, Szabó, Ágnes, Polyák, Helga, Vécsei, László

“…Following introduction of the monoamine oxidase type B inhibitor selegiline for the treatment of Parkinson’s disease (PD), discovery of the action mechanism of…”
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Speech disorders in Parkinson’s disease: early diagnostics and effects of medication and brain stimulation by Brabenec, L., Mekyska, J., Galaz, Z., Rektorova, Irena

“…Hypokinetic dysarthria (HD) occurs in 90% of Parkinson’s disease (PD) patients. It manifests specifically in the areas of articulation, phonation, prosody,…”
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Conservative iron chelation for neurodegenerative diseases such as Parkinson’s disease and amyotrophic lateral sclerosis by Devos, David, Cabantchik, Z. Ioav, Moreau, Caroline, Danel, Véronique, Mahoney-Sanchez, Laura, Bouchaoui, Hind, Gouel, Flore, Rolland, Anne-Sophie, Duce, James A., Devedjian, Jean-Christophe

“…Focal iron accumulation associated with brain iron dyshomeostasis is a pathological hallmark of various neurodegenerative diseases (NDD). The application of…”
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Human tyrosine hydroxylase in Parkinson’s disease and in related disorders by Nagatsu, Toshiharu, Nakashima, Akira, Ichinose, Hiroshi, Kobayashi, Kazuto

“…Parkinson’s disease (PD) is an aging-related movement disorder mainly caused by a deficiency of neurotransmitter dopamine (DA) in the striatum of the brain and…”
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Cross-talk signaling in the trigeminal ganglion: role of neuropeptides and other mediators by Messlinger, Karl, Balcziak, Louis K., Russo, Andrew F.

“…The trigeminal ganglion with its three trigeminal nerve tracts consists mainly of clusters of sensory neurons with their peripheral and central processes. Most…”
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The GlyT1-inhibitor Org 24598 facilitates the alcohol deprivation abolishing and dopamine elevating effects of bupropion plus varenicline in rats by Olsson, Yasmin, Lidö Höifödt, Helga, Ademar, Karin, Cadeddu, Davide, Ericson, Mia, Söderpalm, Bo

“…Alcohol Use Disorder (AUD) is a relapsing brain disorder that involves perturbations of brain dopamine (DA) systems, and combined treatment with varenicline +…”
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Pre-frontal parvalbumin interneurons in schizophrenia: a meta-analysis of post-mortem studies by Kaar, Stephen J., Angelescu, Ilinca, Marques, Tiago Reis, Howes, Oliver D.

“…Parvalbumin interneurons are fast-spiking GABAergic neurons that provide inhibitory control of cortical and subcortical circuits and are thought to be a key…”
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Parkinson’s disease and iron by Mochizuki, Hideki, Choong, Chi-Jing, Baba, Kousuke

“…While the initial causes of Parkinson’s disease (PD) are not clearly defined, iron deposition has long been implicated in the pathogenesis of PD. The…”
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Recent update on the heterogeneity of the Alzheimer’s disease spectrum by Jellinger, Kurt A.

“…Alzheimer’s disease (AD), the most common form of dementia worldwide, is a mixed proteinopathy (β-amyloid, tau and other proteins). Classically defined as a…”
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α-Synuclein in Parkinson’s disease: causal or bystander? by Riederer, Peter, Berg, Daniela, Casadei, Nicolas, Cheng, Fubo, Classen, Joseph, Dresel, Christian, Jost, Wolfgang, Krüger, Rejko, Müller, Thomas, Reichmann, Heinz, Rieß, Olaf, Storch, Alexander, Strobel, Sabrina, van Eimeren, Thilo, Völker, Hans-Ullrich, Winkler, Jürgen, Winklhofer, Konstanze F., Wüllner, Ullrich, Zunke, Friederike, Monoranu, Camelia-Maria

“…Parkinson’s disease (PD) comprises a spectrum of disorders with differing subtypes, the vast majority of which share Lewy bodies (LB) as a characteristic…”
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Amyloid β oligomers (AβOs) in Alzheimer’s disease by Mroczko, Barbara, Groblewska, Magdalena, Litman-Zawadzka, Ala, Kornhuber, Johannes, Lewczuk, Piotr

“…The causative role of amyloid β 1–42 (Aβ42) aggregation in the pathogenesis of Alzheimer’s disease (AD) has been under debate for over 25 years. Primarily,…”
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