Search Results - "Jourd'Heuil, D."

Enhanced S-Nitroso-Albumin Formation From Inhaled NO During Ischemia/Reperfusion by Ng, Ella S.M, Jourd’heuil, David, McCord, Joe M, Hernandez, Daniel, Yasui, Mitsukuni, Knight, Derrice, Kubes, Paul

“…ABSTRACT—In the present study, we investigated whether inhaled nitric oxide (NO) was transported by plasma proteins, such as S-nitroso-albumin (SNO-Alb), in…”
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Review article: chronic inflammation and reactive oxygen and nitrogen metabolism – implications in DNA damage and mutagenesis by Grisham, M. B., Jourd'Heuil, D., Wink, D. A.

“…Summary It is well known that chronic inflammation of the digestive tract is associated with an increased risk of malignant transformation. Because phagocytic…”
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Self-Reported Lower Respiratory Symptoms and Exhaled Nitric Oxide in a WTC-Exposed Cohort by Jones, R, Jourd'heuil, D, Jourd'heuil, F, Hwang, S.A, Lin, S

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Effects of Low Dose combination therapy, Fluticasone Propionate/Salmeterol Combination, 100/50 (FSC 100/50) on Exhaled Nitric Oxide (eNO) and Airway Hyperresponsiveness in Mild Persistent Asthma by Pasha, M.A, Feustel, P.J, Smith, T, Patel, S, Sarathchandra, S, Malone, P, Evans, M, Jourd'heuil, F, Jourd'heuil, D

“…The aim of this study was to investigate the relationship between eNO and airway hyperresponsiveness and whether a combination of an inhaled corticosteroid and…”
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Nitrogen Oxide Metabolites (Nitrite and Nitrate) in Exhaled Breath Condensates (EBC) from Patients with Mild Persistent Asthma, and Effects of Low Dose Combination Therapy Fluticasone Propionate/Salmeterol, 100/50 (FSC 100/50) by Jourd'heuil, D, Feustel, P.J, Smith, T, Patel, S, Sarathchandra, S, Malone, P, Evans, M, Jourd'heuil, F, Pasha, M

“…The aim of the present study was to determine whether nitrite and nitrate could be detected in EBC from patients with mild persistent asthma and investigate…”
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Effects of Low Dose Fluticasone/Salmeterol Combination (Advair 100/50) on Surrogate Inflammatory Markers in Mild Persistent Asthma by Pasha, M.A, Patel, S, Jafri, H, Feustel, P, Sarathchandra, D, Smith, T, Malone, P, Jourd'heuil, F, Jourd'heuil, D

“…Airway hyperresponsiveness, exhaled nitric oxide (ENO) and substances in exhaled breath condensate (EBC) have been proposed as non-invasive markers of…”
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Lipid peroxidation of the brush-border membrane: membrane physical properties and glucose transport by Jourd'Heuil, D, Vaananen, P, Meddings, J B

“…During inflammatory conditions, peroxidation of biological membranes often takes place. Deleterious physiological consequences, in terms of membrane function,…”
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Evaluation of exhaled nitric oxide and nitric oxide metabolites in exhaled breath condensate during asthma by Jourd'heuil, D., Jourd'heuil, F.L., Patil, K.S., Harish, A., Feustel, P.J., Jafri, H., Pasha, M.A.

“…The collection of exhaled breath condensate (EBC) represents a potentially important non-invasive diagnostic tool to sample non-volatile substances from the…”
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Increased nitric oxide-dependent nitrosylation of 4,5-diaminofluorescein by oxidants: implications for the measurement of intracellular nitric oxide by Jourd’heuil, David

“…4,5 Diaminofluorescein (DAF-2) is increasingly utilized as a fluorescent detector for nitric oxide ( NO) in cells and tissues. In oxygenated solutions,…”
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Hemileaflet susceptibility to oxidative damage in the intestinal brush-border membrane by Jourd'heuil, D, Mehta, S, Meddings, J B

“…Oxidation of biological membranes is characteristic of many types of tissue injury, including those observed with inflammatory bowel disease. The lipid…”
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Oxidation and nitrosation of thiols at low micromolar exposure to nitric oxide. Evidence for a free radical mechanism by Jourd'heuil, David, Jourd'heuil, Frances L, Feelisch, Martin

“…Although the nitric oxide (.NO)-mediated nitrosation of thiol-containing molecules is increasingly recognized as an important post-translational modification…”
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Nitric oxide. I. Physiological chemistry of nitric oxide and its metabolites:implications in inflammation by Grisham, M B, Jourd'Heuil, D, Wink, D A

“…The role of nitric oxide (NO) in inflammation represents one of the most studied yet controversial subjects in physiology. A number of reports have…”
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Concomitant S‐, N‐, and heme‐nitros(yl)ation in biological tissues and fluids: implications for the fate of NO in vivo by Feelisch, Martin, Rassaf, Tienush, Mnaimneh, Sanie, Singh, Nisha, Bryan, Nathan S., Jourd'Heuil, David, Kelm, Malte

“…There is growing evidence for the involvement of nitric oxide (NO) ‐mediated nitrosation in cell signaling and pathology. Although S‐nitrosothiols (RSNOs) have…”
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Nitric oxide and the gut by Jourd'heuil, D, Grisham, M B, Granger, D N

“…Nitric oxide (NO) has been implicated as a modulator of blood flow, motility, electrolyte and water transport, and the function of endothelial cells,…”
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Increased opioid binding to peripheral white blood cells in a rat model of acute cholestasis by Lang, M E, Jourd'Heuil, D, Meddings, J B, Swain, M G

“…Endogenous opioids accumulate in plasma in cholestasis. Furthermore, immune cells have opioid receptors, and endogenous opioids have immunomodulatory effects…”
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Interactions between superoxide and nitric oxide: implications in DNA damage and mutagenesis by Jourd'heuil, D, Kang, D, Grisham, M B

“…Chronic inflammation is known to be associated with enhanced production of both nitric oxide (NO) and reactive oxygen species such as superoxide (O2-) and…”
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Performance of diamino fluorophores for the localization of sources and targets of nitric oxide by Rodriguez, Juan, Specian, Victoria, Maloney, Ronald, Jourd'heuil, David, Feelisch, Martin

“…An emergent approach to the detection of nitric oxide (NO) in tissues relies on the use of fluorescence probes that are activated by products of NO…”
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Reaction of superoxide and nitric oxide with peroxynitrite. Implications for peroxynitrite-mediated oxidation reactions in vivo by Jourd'heuil, D, Jourd'heuil, F L, Kutchukian, P S, Musah, R A, Wink, D A, Grisham, M B

“…Peroxynitrite (ONOO(-)/ONOOH), the product of the diffusion-limited reaction of nitric oxide (*NO) with superoxide (O(-*)(2)), has been implicated as an…”
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Hemoprotein-dependent production of a neutrophil-activating factor from arachidonic acid by Wallace, J L, Rioux, K P, McKnight, W, Carter, L, Jourd'heuil, D, Meddings, J, Zimmerman, B J, Granger, D N, Grisham, M B

“…Hemoproteins have been suggested to contribute to various forms of tissue injury by catalyzing the peroxidation of lipids. In this study, the ability of…”
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Effects of reactive metabolites of oxygen and nitrogen on gelatinase A activity by Owens, M W, Milligan, S A, Jourd'heuil, D, Grisham, M B

“…The regulation of matrix metalloproteinase activity is crucial for maintaining the proper balance of tissue remodeling vs. injury. Metalloproteinase proenzymes…”
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