Search Results - "Joubran, Salim"

Enhancing the Efficiency of the Solid Phase Peptide Synthesis (SPPS) Process by High Shear Mixing by Alshanski, Israel, Bentolila, Moshe, Gitlin-Domagalska, Agata, Zamir, Dolev, Zorsky, Shir, Joubran, Salim, Hurevich, Mattan, Gilon, Chaim

“…The brittle nature of the polymer beads used in SPPS dictates mild mixing techniques with low mass transfer. We demonstrate that vigorous overhead mechanical…”
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PSMA-targeted polyinosine/polycytosine vector induces prostate tumor regression and invokes an antitumor immune response in mice by Langut, Yael, Talhami, Alaa, Mamidi, Samarasimhareddy, Shir, Alexei, Zigler, Maya, Joubran, Salim, Sagalov, Anna, Flashner-Abramson, Efrat, Edinger, Nufar, Klein, Shoshana, Levitzki, Alexander

“…There is an urgent need for an effective treatment for metastatic prostate cancer (PC). Prostate tumors invariably overexpress prostate surface membrane…”
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Optimization of Liganded Polyethylenimine Polyethylene Glycol Vector for Nucleic Acid Delivery by Joubran, Salim, Zigler, Maya, Pessah, Neta, Klein, Shoshana, Shir, Alexei, Edinger, Nufar, Sagalov, Anna, Razvag, Yair, Reches, Meital, Levitzki, Alexander

“…The delivery of nucleic acids into cells is an attractive approach for cancer therapy. Polyethylenimine (PEI) is among the most efficient nonviral carriers…”
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Superiority of the S,S conformation in diverse pharmacological processes: Intestinal transport and entry inhibition activity of novel anti-HIV drug lead by Fanous, Joseph, Swed, Avi, Joubran, Salim, Hurevich, Mattan, Britan-Rosich, Elena, Kotler, Moshe, Gilon, Chaim, Hoffman, Amnon

“…[Display omitted] Chirality is an important aspect in many pharmacological processes including drug transport and metabolism. The current investigation…”
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Abstract B243: Targeting HER-2 positive breast cancer by inducing apoptosis and immune cell activation, overcoming trastuzumab resistance by Zigler, Maya, Joubran, Salim, Shir, Alexei, Edinger, Noofar, Klein, Shoshana, Levitzki, Alexander

“…Abstract Breast cancer is the most common cancer in women and the second leading cause of cancer-related deaths in females. Overexpression of HER-2 occurs in…”
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HER2-Targeted Polyinosine/Polycytosine Therapy Inhibits Tumor Growth and Modulates the Tumor Immune Microenvironment by Zigler, Maya, Shir, Alexei, Joubran, Salim, Sagalov, Anna, Klein, Shoshana, Edinger, Nufar, Lau, Jeffrey, Yu, Shang-Fan, Mizraji, Gabriel, Globerson Levin, Anat, Sliwkowski, Mark X, Levitzki, Alexander

“…The development of targeted therapies that affect multiple signaling pathways and stimulate antitumor immunity is greatly needed. About 20% of patients with…”
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Rational conversion of noncontinuous active region in proteins into a small orally bioavailable macrocyclic drug-like molecule: The HIV-1 CD4:gp120 paradigm by Hurevich, Mattan, Swed, Avi, Joubran, Salim, Cohen, Shira, Freeman, Noam S., Britan-Rosich, Elena, Briant-Longuet, Laurence, Bardy, Martine, Devaux, Christian, Kotler, Moshe, Hoffman, Amnon, Gilon, Chaim

“…Screening of backbone cyclic peptide library: an intermediate step in rational design of orally available macrocyclic HIV-1 infection inhibitor that mimics…”
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