Search Results - "Joubert, Pierre Emmanuel"

Sumoylation coordinates the repression of inflammatory and anti-viral gene-expression programs during innate sensing by Decque, Adrien, Joffre, Olivier, Magalhaes, Joao G, Cossec, Jack-Christophe, Blecher-Gonen, Ronnie, Lapaquette, Pierre, Silvin, Aymeric, Manel, Nicolas, Joubert, Pierre-Emmanuel, Seeler, Jacob-Sebastian, Albert, Matthew L, Amit, Ido, Amigorena, Sebastian, Dejean, Anne

“…Sumolyation regulates wide-ranging biological processes, but its influence on innate immunity is unclear. Amigorena and colleagues show that sumoylation…”
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Chikungunya virus-induced autophagy delays caspase-dependent cell death by Joubert, Pierre-Emmanuel, Werneke, Scott W, de la Calle, Claire, Guivel-Benhassine, Florence, Giodini, Alessandra, Peduto, Lucie, Levine, Beth, Schwartz, Olivier, Lenschow, Deborah J, Albert, Matthew L

“…Autophagy is an important survival pathway and can participate in the host response to infection. Studying Chikungunya virus (CHIKV), the causative agent of a…”
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Autophagy Modulation by Viral Infections Influences Tumor Development by Leonardi, Lucas, Sibéril, Sophie, Alifano, Marco, Cremer, Isabelle, Joubert, Pierre-Emmanuel

“…Autophagy is a self-degradative process important for balancing cellular homeostasis at critical times in development and/or in response to nutrient stress…”
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Autophagy induction by the pathogen receptor CD46 by Joubert, Pierre-Emmanuel, Meiffren, Grégory, Grégoire, Isabel Pombo, Pontini, Guillemette, Richetta, Clémence, Flacher, Monique, Azocar, Olga, Vidalain, Pierre-Olivier, Vidal, Marc, Lotteau, Vincent, Codogno, Patrice, Rabourdin-Combe, Chantal, Faure, Mathias

“…Autophagy is a highly regulated self-degradative mechanism required at a basal level for intracellular clearance and recycling of cytoplasmic contents. Upon…”
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Unraveling the complex interplay between anti-tumor immune response and autoimmunity mediated by B cells and autoantibodies in the era of anti-checkpoint monoclonal antibody therapies by Soussan, Sarah, Pupier, Guilhem, Cremer, Isabelle, Joubert, Pierre-Emmanuel, Sautès-Fridman, Catherine, Fridman, Wolf Herman, Sibéril, Sophie

“…The intricate relationship between anti-tumor immunity and autoimmunity is a complex yet crucial aspect of cancer biology. Tumor microenvironment often…”
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Inhibition of mTORC1 Enhances the Translation of Chikungunya Proteins via the Activation of the MnK/eIF4E Pathway by Joubert, Pierre-Emmanuel, Stapleford, Kenneth, Guivel-Benhassine, Florence, Vignuzzi, Marco, Schwartz, Olivier, Albert, Matthew L

“…Chikungunya virus (CHIKV), the causative agent of a major epidemic spanning five continents, is a positive stranded mRNA virus that replicates using the cell's…”
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IRGM is a common target of RNA viruses that subvert the autophagy network by Grégoire, Isabel Pombo, Richetta, Clémence, Meyniel-Schicklin, Laurène, Borel, Sophie, Pradezynski, Fabrine, Diaz, Olivier, Deloire, Alexandre, Azocar, Olga, Baguet, Joël, Le Breton, Marc, Mangeot, Philippe E, Navratil, Vincent, Joubert, Pierre-Emmanuel, Flacher, Monique, Vidalain, Pierre-Olivier, André, Patrice, Lotteau, Vincent, Biard-Piechaczyk, Martine, Rabourdin-Combe, Chantal, Faure, Mathias

“…Autophagy is a conserved degradative pathway used as a host defense mechanism against intracellular pathogens. However, several viruses can evade or subvert…”
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Natural killer cells in the human lung tumor microenvironment display immune inhibitory functions by Russick, Jules, Joubert, Pierre-Emmanuel, Gillard-Bocquet, Mélanie, Torset, Carine, Meylan, Maxime, Petitprez, Florent, Dragon-Durey, Marie-Agnes, Marmier, Solenne, Varthaman, Aditi, Josseaume, Nathalie, Germain, Claire, Goc, Jérémy, Dieu-Nosjean, Marie-Caroline, Validire, Pierre, Fournel, Ludovic, Zitvogel, Laurence, Bindea, Gabriela, Lupo, Audrey, Damotte, Diane, Alifano, Marco, Cremer, Isabelle

“…BackgroundNatural killer (NK) cells play a crucial role in tumor immunosurveillance through their cytotoxic effector functions and their capacity to interact…”
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Plasmacytoid dendritic cells control dengue and Chikungunya virus infections via IRF7-regulated interferon responses by Webster, Brian, Werneke, Scott W, Zafirova, Biljana, This, Sébastien, Coléon, Séverin, Décembre, Elodie, Paidassi, Helena, Bouvier, Isabelle, Joubert, Pierre-Emmanuel, Duffy, Darragh, Walzer, Thierry, Albert, Matthew L, Dreux, Marlène

“…Type I interferon (IFN-I) responses are critical for the control of RNA virus infections, however, many viruses, including Dengue (DENV) and Chikungunya…”
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Chikungunya-induced cell death is limited by ER and oxidative stress-induced autophagy by Joubert, Pierre-Emmanuel, Werneke, Scott, de la Calle, Claire, Guivel-Benhassine, Florence, Giodini, Alessandra, Peduto, Lucie, Levine, Beth, Schwartz, Olivier, Lenschow, Deborah, Albert, Matthew L.

“…It has been recognized that macroautophagy constitutes an important survival mechanism that allows both the maintenance of cellular homeostasis and the…”
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Simultaneous assessment of autophagy and apoptosis using multispectral imaging cytometry by de la Calle, Claire, Joubert, Pierre-Emmanuel, Law, Helen K.W., Hasan, Milena, Albert, Matthew

“…Multiple stress pathways result in the induction of autophagy and apoptosis. Current methods (e.g., protein gel blot, microscopy) do not offer quantitative…”
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Pathogen recognition by the cell surface receptor CD46 induces autophagy by Meiffren, Grégory, Joubert, Pierre-Emmanuel, Grégoire, Isabel Pombo, Codogno, Patrice, Rabourdin-Combe, Chantal, Faure, Mathias

“…Autophagy is a degradative mechanism involved in cell protection against invading pathogens. Although the autophagic process is well characterized, the…”
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Autophagy-Related Gene Signature Highlights Metabolic and Immunogenic Status of Malignant Cells in Non-Small Cell Lung Cancer Adenocarcinoma by Leonardi, Lucas, Siberil, Sophie, Alifano, Marco, Cremer, Isabelle, Joubert, Pierre-Emmanuel

“…Autophagy is a self-degradative mechanism involved in many biological processes, including cell death, survival, proliferation or migration. In tumors,…”
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Toll like receptor 7 expressed by malignant cells promotes tumor progression and metastasis through the recruitment of myeloid derived suppressor cells by Dajon, Marion, Iribarren, Kristina, Petitprez, Florent, Marmier, Solenne, Lupo, Audrey, Gillard, Mélanie, Ouakrim, Hanane, Victor, Navas, Vincenzo, Di Bartolo, Joubert, Pierre Emmanuel, Kepp, Oliver, Kroemer, Guido, Alifano, Marco, Damotte, Diane, Cremer, Isabelle

“…In non-small cell lung carcinoma (NSCLC), stimulation of toll-like receptor 7 (TLR7), a receptor for single stranded RNA, is linked to tumor progression and…”
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Acute Influenza Infection Promotes Lung Tumor Growth by Reprogramming the Tumor Microenvironment by Garmendia, Irati, Varthaman, Aditi, Marmier, Solenne, Angrini, Mahmud, Matchoua, Ingrid, Darbois-Delahousse, Aurelie, Josseaume, Nathalie, Foy, Pierre-Emmanuel, Roumenina, Lubka T, Naouar, Naïra, Meylan, Maxime, Sibéril, Sophie, Russick, Jules, Joubert, Pierre-Emmanuel, Leroy, Karen, Damotte, Diane, Mansuet-Lupo, Audrey, Wislez, Marie, Alifano, Marco, Menger, Laurie, Garcia-Verdugo, Ignacio, Sallenave, Jean-Michel, Lantz, Olivier, Petitprez, Florent, Cremer, Isabelle

“…One billion people worldwide get flu every year, including patients with non-small cell lung cancer (NSCLC). However, the impact of acute influenza A virus…”
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Tumor stage-driven disruption of NK cell maturation in human and murine tumors by Russick, Jules, Torset, Carine, Sun, Dan, Marmier, Solenne, Merle, Nicolas, Voilin, Elodie, Josseaume, Nathalie, Meylan, Maxime, Hernandez, Isaïas, Foy, Pierre-Emmanuel, Joubert, Pierre-Emmanuel, Alifano, Marco, Lupo, Audrey, Siberil, Sophie, Björkström, Niklas K., Damotte, Diane, Cremer, Isabelle

“…Natural killer (NK) cells play a pivotal role against cancer, both by direct killing of malignant cells and by promoting adaptive immune response though…”
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Antigen Cross-Priming of Cell-Associated Proteins is Enhanced by Macroautophagy within the Antigen Donor Cell by Joubert, Pierre-Emmanuel, Albert, Matthew L

“…Phagocytosis of dying cells constitutes an important mechanism of antigen capture for the cross-priming of CD8(+) T cells. This process has been shown to be…”
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Plasticity of programmed cell death pathways while fighting Salmonella, plenty of possibilities to defend against pathogens by Chemin, Gabriel, De Giacomoni, Antoine, Joubert, Pierre-Emmanuel

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Autophagy modulation by viruses: An important role in tumor progression by Leonardi, Lucas, Sibéril, Sophie, Alifano, Marco, Cremer, Isabelle, Joubert, Pierre-Emmanuel

“…Autophagy is an important process for cellular homeostasis at critical steps of development or in response to environmental stress. In the context of cancers,…”
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Inhibition of mTORC1 Enhances the Translation of Chikungunya Proteins via the Activation of the MnK/eIF4E Pathway: e1005091 by Joubert, Pierre-Emmanuel, Stapleford, Kenneth, Guivel-Benhassine, Florence, Vignuzzi, Marco, Schwartz, Olivier, Albert, Matthew L

“…Chikungunya virus (CHIKV), the causative agent of a major epidemic spanning five continents, is a positive stranded mRNA virus that replicates using the cell's…”
Get full text