Search Results - "Joubert, Bonnie"
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Statistical Approaches for Assessing Health Effects of Environmental Chemical Mixtures in Epidemiology: Lessons from an Innovative Workshop
Published in Environmental health perspectives (01-12-2016)“…Quantifying the impact of exposure to environmental chemical mixtures is important for identifying risk factors for diseases and developing more targeted…”
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Small-Magnitude Effect Sizes in Epigenetic End Points are Important in Children's Environmental Health Studies: The Children's Environmental Health and Disease Prevention Research Center's Epigenetics Working Group
Published in Environmental health perspectives (01-04-2017)“…Characterization of the epigenome is a primary interest for children's environmental health researchers studying the environmental influences on human…”
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Review of developmental origins of health and disease publications in environmental epidemiology
Published in Reproductive toxicology (Elmsford, N.Y.) (01-03-2017)“…•The epidemiology literature focused on the DOHaD paradigm is quite robust.•Sixty different chemicals have been studied in the epidemiology literature.•Most…”
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Prenatal tobacco smoke exposure is associated with childhood DNA CpG methylation
Published in PloS one (25-06-2014)“…Smoking while pregnant is associated with a myriad of negative health outcomes in the child. Some of the detrimental effects may be due to epigenetic…”
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Maternal Age at Delivery Is Associated with an Epigenetic Signature in Both Newborns and Adults
Published in PloS one (06-07-2016)“…Offspring of older mothers are at increased risk of adverse birth outcomes, childhood cancers, type 1 diabetes, and neurodevelopmental disorders. The…”
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450K Epigenome-Wide Scan Identifies Differential DNA Methylation in Newborns Related to Maternal Smoking during Pregnancy
Published in Environmental health perspectives (01-10-2012)“…Background: Epigenetic modifications, such as DNA methylation, due to in utero exposures may play a critical role in early programming for childhood and adult…”
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DNA Methylation Score as a Biomarker in Newborns for Sustained Maternal Smoking during Pregnancy
Published in Environmental health perspectives (01-04-2017)“…Maternal smoking during pregnancy, especially when sustained, leads to numerous adverse health outcomes in offspring. Pregnant women disproportionately…”
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Cardiopulmonary Impact of Particulate Air Pollution in High-Risk Populations: JACC State-of-the-Art Review
Published in Journal of the American College of Cardiology (15-12-2020)“…Fine particulate air pollution <2.5 μm in diameter (PM ) is a major environmental threat to global public health. Multiple national and international medical…”
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Powering Research through Innovative Methods for Mixtures in Epidemiology (PRIME) Program: Novel and Expanded Statistical Methods
Published in International journal of environmental research and public health (26-01-2022)“…Humans are exposed to a diverse mixture of chemical and non-chemical exposures across their lifetimes. Well-designed epidemiology studies as well as…”
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Environmental Health Research in Africa: Important Progress and Promising Opportunities
Published in Frontiers in genetics (16-01-2020)“…The World Health Organization in 2016 estimated that over 20% of the global disease burden and deaths were attributed to modifiable environmental factors…”
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Chronic kidney diseases in agricultural communities: report from a workshop
Published in Kidney international (01-11-2019)“…In June 2018, the National Institute of Diabetes and Digestive and Kidney Diseases and the National Institute of Environmental Health Sciences sponsored a…”
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Maternal Smoking and DNA Methylation in Newborns: In Utero Effect or Epigenetic Inheritance?
Published in Cancer epidemiology, biomarkers & prevention (01-06-2014)“…Maternal smoking in pregnancy is associated with adverse health outcomes in children, including cancers; underlying mechanisms may include epigenetic…”
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Building blocks for better biorepositories in Africa
Published in Genome medicine (06-11-2023)“…Biorepositories archive and distribute well-characterized biospecimens for research to support the development of medical diagnostics and therapeutics…”
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Neonatal Genome-Wide Methylation Patterns in Relation to Birth Weight in the Norwegian Mother and Child Cohort
Published in American journal of epidemiology (01-04-2014)“…Although epigenetic regulation plays a critical role in embryonic development, few studies have examined the relationship of epigenome-wide methylation with…”
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The Trial to Assess Chelation Therapy 2 (TACT2): Rationale and Design
Published in The American heart journal (01-10-2022)“…The Trial to Assess Chelation Therapy 2 (TACT2) is an NIH-sponsored, randomized, 2x2 factorial, double masked, placebo-controlled, multicenter clinical trial…”
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Baseline characteristics including blood and urine metal levels in the Trial to Assess Chelation Therapy 2 (TACT2)
Published in The American heart journal (01-07-2024)“…The reduction in cardiovascular disease (CVD) events with edetate disodium (EDTA) in the Trial to Assess Chelation Therapy (TACT) suggested that chelation of…”
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Maternal smoking impacts key biological pathways in newborns through epigenetic modification in Utero
Published in BMC genomics (25-11-2016)“…Children exposed to maternal smoking during pregnancy exhibit increased risk for many adverse health effects. Maternal smoking influences methylation in…”
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Contrasting the effects of intra-uterine smoking and one-carbon micronutrient exposures on offspring DNA methylation
Published in Epigenomics (01-03-2017)“…Maternal smoking and micronutrient intake during pregnancy are two strong biological candidates for impacting the developing epigenome. The extent to which DNA…”
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A systematic assessment of normalization approaches for the Infinium 450K methylation platform
Published in Epigenetics (01-02-2014)“…The Illumina Infinium HumanMethylation450 BeadChip has emerged as one of the most popular platforms for genome wide profiling of DNA methylation. While the…”
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Epigenome-wide association study of serum folate in maternal peripheral blood leukocytes
Published in Epigenomics (01-01-2023)“…To perform an epigenome-wide association study (EWAS) of serum folate in maternal blood. Cross-ancestry (Europeans = 302, South Asians = 161) and…”
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