Search Results - "Jouanin, Aurélie"
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Outlook for coeliac disease patients: towards bread wheat with hypoimmunogenic gluten by gene editing of α- and γ-gliadin gene families
Published in BMC plant biology (01-08-2019)“…Wheat grains contain gluten proteins, which harbour immunogenic epitopes that trigger Coeliac disease in 1-2% of the human population. Wheat varieties or…”
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Development of Wheat With Hypoimmunogenic Gluten Obstructed by the Gene Editing Policy in Europe
Published in Frontiers in plant science (18-10-2018)“…Coeliac Disease (CD) is an auto-immune reaction to gluten in 1-2% of the human population. A gluten-free (GF) diet, excluding wheat, barley, and rye, is the…”
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Optimisation of droplet digital PCR for determining copy number variation of α-gliadin genes in mutant and gene-edited polyploid bread wheat
Published in Journal of cereal science (01-03-2020)“…Targeted and random mutagenesis of gene families require accurate quantification. Droplet digital PCR (ddPCR) enables high-throughput screening of copy number…”
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Food processing and breeding strategies for coeliac-safe and healthy wheat products
Published in Food research international (01-08-2018)“…A strict gluten-free diet is currently the only treatment for the 1–2% of the world population who suffer from coeliac disease (CD). However, due to the…”
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Development of the GlutEnSeq capture system for sequencing gluten gene families in hexaploid bread wheat with deletions or mutations induced by γ-irradiation or CRISPR/Cas9
Published in Journal of cereal science (01-07-2019)“…We developed an in-solution gluten exome capture system called GlutEnSeq (Gluten gene Enrichment and Sequencing), covering the sequence variation of thousands…”
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CRISPR/Cas9 Gene Editing of Gluten in Wheat to Reduce Gluten Content and Exposure-Reviewing Methods to Screen for Coeliac Safety
Published in Frontiers in nutrition (Lausanne) (24-04-2020)“…Ingestion of gluten proteins (gliadins and glutenins) from wheat, barley and rye can cause coeliac disease (CD) in genetically predisposed individuals. The…”
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Development of wheat with hypoimmunogenic gluten obstructed by the gene editing policy in europe
Published in Frontiers in plant science (2018)“…Coeliac Disease (CD) is an auto-immune reaction to gluten in 1–2% of the human population. A gluten-free (GF) diet, excluding wheat, barley, and rye, is the…”
Get full text
Journal Article -
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Outlook for coeliac disease patients: towards bread wheat with hypoimmunogenic gluten by gene editing of [alpha]- and [gamma]-gliadin gene families
Published in BMC plant biology (01-08-2019)“…Wheat grains contain gluten proteins, which harbour immunogenic epitopes that trigger Coeliac disease in 1-2% of the human population. Wheat varieties or…”
Get full text
Journal Article -
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Gene Editing towards Hypoimmunogenic Gluten Proteins in Wheat
Published 01-01-2019“…Bread wheat (Triticum aestivum) is an allohexaploid plant, with a genome size five times bigger than the human genome. It is worldwide the third staple crop,…”
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