Search Results - "Josvay, Katalin"
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Contribution of syndecans to cellular uptake and fibrillation of α-synuclein and tau
Published in Scientific reports (12-11-2019)“…Scientific evidence suggests that α-synuclein and tau have prion-like properties and that prion-like spreading and seeding of misfolded protein aggregates…”
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Contribution of syndecans to cellular internalization and fibrillation of amyloid-β(1–42)
Published in Scientific reports (04-02-2019)“…Intraneuronal accumulation of amyloid-β(1–42) (Aβ1–42) is one of the earliest signs of Alzheimer’s disease (AD). Cell surface heparan sulfate proteoglycans…”
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3
The Interplay of Apoes with Syndecans in Influencing Key Cellular Events of Amyloid Pathology
Published in International journal of molecular sciences (01-07-2021)“…Apolipoprotein E (ApoE) isoforms exert intricate effects on cellular physiology beyond lipid transport and metabolism. ApoEs influence the onset of Alzheimer’s…”
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Activation of endogenous TRPV1 fails to induce overstimulation-based cytotoxicity in breast and prostate cancer cells but not in pain-sensing neurons
Published in Biochimica et biophysica acta (01-08-2016)“…Vanilloids including capsaicin and resiniferatoxin are potent transient receptor potential vanilloid type 1 (TRPV1) agonists. TRPV1 overstimulation selectively…”
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5
Targeting breast cancer cells by MRS1477, a positive allosteric modulator of TRPV1 channels
Published in PloS one (22-06-2017)“…There is convincing epidemiological and experimental evidence that capsaicin, a potent natural transient receptor potential cation channel vanilloid member 1…”
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Simvastatin, edaravone and dexamethasone protect against kainate-induced brain endothelial cell damage
Published in Fluids and barriers of the CNS (10-02-2020)“…Excitotoxicity is a central pathological pathway in many neurological diseases with blood-brain barrier (BBB) dysfunction. Kainate, an exogenous excitotoxin,…”
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Functionally Important Amino Acid Residues in the Transient Receptor Potential Vanilloid 1 (TRPV1) Ion Channel - An Overview of the Current Mutational Data
Published in Molecular Pain (22-06-2013)“…This review aims to create an overview of the currently available results of site-directed mutagenesis studies on transient receptor potential vanilloid type 1…”
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Menthol evokes Ca2+ signals and induces oxidative stress independently of the presence of TRPM8 (menthol) receptor in cancer cells
Published in Redox biology (01-04-2018)“…Menthol is a naturally occurring monoterpene alcohol possessing remarkable biological properties including antipruritic, analgesic, antiseptic,…”
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9
Involvement of small heat shock proteins, trehalose, and lipids in the thermal stress management in Schizosaccharomyces pombe
Published in Cell stress & chaperones (01-03-2016)“…Changes in the levels of three structurally and functionally different important thermoprotectant molecules, namely small heat shock proteins (sHsps),…”
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Pellitorine, an extract of Tetradium daniellii, is an antagonist of the ion channel TRPV1
Published in Phytomedicine (Stuttgart) (15-10-2017)“…Transient Receptor Potential Vanilloid 1 (TRPV1) confers noxious heat and inflammatory pain signals in the peripheral nervous system. Clinical trial of…”
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Competitive inhibition of TRPV1–calmodulin interaction by vanilloids
Published in FEBS letters (01-08-2016)“…There is enormous interest toward vanilloid agonists of the pain receptor TRPV1 in analgesic therapy, but the mechanisms of their sensory neuron‐blocking…”
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12
Human keratinocytes are vanilloid resistant
Published in PloS one (14-10-2008)“…Use of capsaicin or resiniferatoxin (RTX) as analgesics is an attractive therapeutic option. RTX opens the cation channel inflammatory pain/vanilloid receptor…”
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13
Besides neuro-imaging, the Thy1-YFP mouse could serve for visualizing experimental tumours, inflammation and wound-healing
Published in Scientific reports (27-10-2014)“…The B6.Cg-Tg(Thy1-YFP)16Jrs/J transgenic mouse strain, widely used to study neuronal development and regeneration, expresses the yellow fluorescent protein…”
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Anti-calmodulins and tricyclic adjuvants in pain therapy block the TRPV1 channel
Published in PloS one (20-06-2007)“…Ca(2+)-loaded calmodulin normally inhibits multiple Ca(2+)-channels upon dangerous elevation of intracellular Ca(2+) and protects cells from…”
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Divalent Heavy Metal Cations Block the TRPV1 Ca²⁺ Channel
Published in Biological trace element research (01-03-2013)“…Transient receptor potential vanilloid 1 (TRPV1) is a non-selective cation channel involved in pain sensation and in a wide range of non-pain-related…”
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16
“Heat shock lipid” in cyanobacteria during heat/light-acclimation
Published in Archives of biochemistry and biophysics (15-04-2005)“…Parallel with the heat/light-induced thylakoid microdomain reorganization and thermal stabilization of photosynthesis we observed an increase in the level of…”
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Only one dnaK homolog, dnaK2, is active transcriptionally and is essential in Synechocystis
Published in Biochemical and biophysical research communications (06-06-2003)“…We examined the expression and the function of the DnaK chaperone family in the photoautotrophic cyanobacterium, Synechocystis PCC 6803. Surprisingly, only one…”
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Divalent Heavy Metal Cations Block the TRPV1 Ca super(2+) Channel
Published in Biological trace element research (01-03-2013)“…Transient receptor potential vanilloid 1 (TRPV1) is a non-selective cation channel involved in pain sensation and in a wide range of non-pain-related…”
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19
Menthol evokes Ca 2+ signals and induces oxidative stress independently of the presence of TRPM8 (menthol) receptor in cancer cells
Published in Redox biology (01-04-2018)“…Menthol is a naturally occurring monoterpene alcohol possessing remarkable biological properties including antipruritic, analgesic, antiseptic,…”
Get full text
Journal Article -
20
Divalent heavy metal cations block the TRPV1 Ca(2+) channel
Published in Biological trace element research (01-03-2013)“…Transient receptor potential vanilloid 1 (TRPV1) is a non-selective cation channel involved in pain sensation and in a wide range of non-pain-related…”
Get full text
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