Search Results - "Jost, Edgar"

Patient-tailored adoptive immunotherapy with EBV-specific T cells from related and unrelated donors by Bonifacius, Agnes, Lamottke, Britta, Tischer-Zimmermann, Sabine, Schultze-Florey, Rebecca, Goudeva, Lilia, Heuft, Hans-Gert, Arseniev, Lubomir, Beier, Rita, Beutel, Gernot, Cario, Gunnar, Fröhlich, Birgit, Greil, Johann, Hansmann, Leo, Hasenkamp, Justin, Höfs, Michaela, Hundsdoerfer, Patrick, Jost, Edgar, Kafa, Kinan, Kriege, Oliver, Kröger, Nicolaus, Mathas, Stephan, Meisel, Roland, Nathrath, Michaela, Putkonen, Mervi, Ravens, Sarina, Reinhardt, Hans Christian, Sala, Elisa, Sauer, Martin G, Schmitt, Clemens, Schroers, Roland, Steckel, Nina Kristin, Trappe, Ralf Ulrich, Verbeek, Mareike, Wolff, Daniel, Blasczyk, Rainer, Eiz-Vesper, Britta, Maecker-Kolhoff, Britta

“…BACKGROUNDAdoptive transfer of EBV-specific T cells can restore specific immunity in immunocompromised patients with EBV-associated complications.METHODSWe…”
Get full text

Quantification of hematopoietic stem and progenitor cells by targeted DNA methylation analysis by Bocova, Ledio, Hubens, Wouter, Engel, Cordula, Koschmieder, Steffen, Jost, Edgar, Wagner, Wolfgang

“…Hematopoietic stem and progenitor cells (HSPCs) are quantified in daily clinical practice by flow cytometry. In this study, we provide proof of concept that…”
Get full text

Correction: Quantification of hematopoietic stem and progenitor cells by targeted DNA methylation analysis by Bocova, Ledio, Hubens, Wouter, Engel, Cordula, Koschmieder, Steffen, Jost, Edgar, Wagner, Wolfgang

Get full text

Time from diagnosis to treatment has no impact on survival in newly diagnosed acute myeloid leukemia treated with venetoclax-based regimens by Baden, David, Zukunft, Sven, Hernandez, Gema, Wolgast, Nadine, Steinhauser, Sophie, Pohlmann, Alexander, Schliemann, Christoph, Mikesch, Jan-Henrik, Steffen, Bjorn, Sauer, Tim, Hanoun, Maher, Schafer-Eckart, Kerstin, Krause, Stefan W, Hanel, Mathias, Einsele, Hermann, Jost, Edgar, Brummendorf, Tim H, Scholl, Sebastian, Hochhaus, Andreas, Neubauer, Andreas, Burchert, Andreas, Kaufmann, Martin, Niemann, Dirk, Schaich, Markus, Blau, Wolfgang, Kiani, Alexander, Gorner, Martin, Kaiser, Ulrich, Kullmer, Johannes, Weber, Thomas, Berdel, Wolfgang E, Ehninger, Gerhard, Muller-Tidow, Carsten, Platzbecker, Uwe, Serve, Hubert, Bornhauser, Martin, Rollig, Christoph, Baldus, Claudia D, Fransecky, Lars

“…In newly diagnosed acute myeloid leukemia (AML), immediate initiation of treatment is standard of care. However, deferral of antileukemic therapy may be…”
Get full text

Impact of trisomy 19 on outcome according to genetic makeup in patients with acute myeloid leukemia by Kayser, Sabine, Martínez-Cuadrón, David, Rodriguez-Veiga, Rebeca, Hänel, Mathias, Tormo, Mar, Schäfer-Eckart, Kerstin, Botella, Carmen, Stölzel, Friedrich, Del Castillo, Teresa Bernal, Keller, Ulrich, Rodriguez-Medina, Carlos, Held, Gerhard, Amigo, Maria-Luz, Schliemann, Christoph, Colorado, Mercedes, Kaufmann, Martin, Garcia, Manuel Barrios, Krause, Stefan W, Görner, Martin, Jost, Edgar, Steffen, Björn, Zukunft, Sven, Platzbecker, Uwe, Ho, Anthony D, Baldus, Claudia D, Serve, Hubert, Müller-Tidow, Carsten, Thiede, Christian, Bornhäuser, Martin, Montesinos, Pau, Röllig, Christoph, Schlenk, Richard F

“…We retrospectively studied 97 acute myeloid leukemia patients with trisomy 19 (median age at diagnosis 57 years; range, 17- 83 years) treated between 2001 and…”
Get full text

Tracking myeloid malignancies by targeted analysis of successive DNA methylation at neighboring CG dinucleotides by Eipel, Monika, Božić, Tanja, Mies, Anna, Beier, Fabian, Jost, Edgar, Brümmendorf, Tim H, Platzbecker, Uwe, Wagner, Wolfgang

Get full text

DDX41 germline variants causing donor cell leukemia indicate a need for further genetic workup in the context of hematopoietic stem cell transplantation by Rolles, Benjamin, Meyer, Robert, Begemann, Matthias, Elbracht, Miriam, Jost, Edgar, Stelljes, Matthias, Kurth, Ingo, Brümmendorf, Tim H., Silling, Gerda

Get full text

Promoter hypermethylation of the SFRP2 gene is a high-frequent alteration and tumor-specific epigenetic marker in human breast cancer by Veeck, Jürgen, Noetzel, Erik, Bektas, Nuran, Jost, Edgar, Hartmann, Arndt, Knüchel, Ruth, Dahl, Edgar

“…We have previously reported that expression of the Wnt antagonist genes SFRP1 and SFRP5 is frequently silenced by promoter hypermethylation in breast cancer…”
Get full text

A systematic comparison of quantitative high-resolution DNA methylation analysis and methylation-specific PCR by Claus, Rainer, Wilop, Stefan, Hielscher, Thomas, Sonnet, Miriam, Dahl, Edgar, Galm, Oliver, Jost, Edgar, Plass, Christoph

“…Assessment of DNA methylation has become a critical factor for the identification, development and application of methylation based biomarkers. Here we…”
Get full text

Ubiquitin carboxyl-terminal hydrolase 1 (UCHL1) is a potential tumour suppressor in prostate cancer and is frequently silenced by promoter methylation by Ummanni, Ramesh, Jost, Edgar, Braig, Melanie, Lohmann, Frithjof, Mundt, Frederike, Barett, Christine, Schlomm, Thorsten, Sauter, Guido, Senff, Tina, Bokemeyer, Carsten, Sültmann, Holger, Meyer-Schwesinger, Catherine, Brümmendorf, Tim H, Balabanov, Stefan

“…We have previously reported significant downregulation of ubiquitin carboxyl-terminal hydrolase 1 (UCHL1) in prostate cancer (PCa) compared to the surrounding…”
Get full text

Granzyme B-H22(scFv), a human immunotoxin targeting CD64 in acute myeloid leukemia of monocytic subtypes by Stahnke, Bettina, Thepen, Theo, Stöcker, Michael, Rosinke, Reinhard, Jost, Edgar, Fischer, Rainer, Tur, Mehmet K, Barth, Stefan

“…Acute myeloid leukemia (AML) cells of subtypes M4 and M5 show enhanced expression of CD64 (FcγRI), the high-affinity receptor for IgG, which is normally…”
Get full text

Application of wearables for remote monitoring of oncology patients: A scoping review by Cloß, Katharina, Verket, Marlo, Müller-Wieland, Dirk, Marx, Nikolaus, Schuett, Katharina, Jost, Edgar, Crysandt, Martina, Beier, Fabian, Brümmendorf, Tim H, Kobbe, Guido, Brandts, Julia, Jacobsen, Malte

“…This review aims to systematically map and categorize the current state of wearable applications among oncology patients and to identify determinants impeding…”
Get full text

Presence of TERT Promoter Mutations is a Secondary Event and Associates with Elongated Telomere Length in Myxoid Liposarcomas by Ferreira, Monica S Ventura, Crysandt, Martina, Braunschweig, Till, Jost, Edgar, Voss, Barbara, Bouillon, Anne-Sophie, Knuechel, Ruth, Brümmendorf, Tim H, Beier, Fabian

“…The occurrence of promoter mutations has been well described in soft tissue sarcomas (STS). However, the biological role of these mutations as well as their…”
Get full text

Sorafenib As Maintenance Therapy Post Allogeneic Stem Cell Transplantation for FLT3-ITD Positive AML: Results from the Randomized, Double-Blind, Placebo-Controlled Multicentre Sormain Trial by Burchert, Andreas, Bug, Gesine, Finke, Jürgen, Stelljes, Matthias, Rollig, Christoph, Wäsch, Ralph, Bornhäuser, Martin, Berg, Tobias, Lang, Fabian, Ehninger, Gerhard, Serve, Hubert, Zeiser, Robert, Wagner, Eva-Maria, Kroeger, Nicolaus, Wolschke, Christine, Schleuning, Michael, Elmaagacli, Ahmet, Götze, Katharina S., Schmid, Christoph, Jost, Edgar, Wolf, Dominik, Böhm, Alexandra, Thiede, Christian, Haferlach, Torsten, Bethge, Wolfgang, Harnisch, Susanne, Wittenberg, Michael, Rospleszcz, Susanne, Neubauer, Andreas, Brugger, Markus, Strauch, Konstantin, Schade-Brittinger, Carmen, Metzelder, Stephan K

“…▪ Introduction: Most patients with FLT3-ITD-positive AML, who relapse after allogenic stem cell transplantation (allo-SCT) die from their disease. Whether…”
Get full text

MicroRNAs and Metabolites in Serum Change after Chemotherapy: Impact on Hematopoietic Stem and Progenitor Cells by Walenda, Thomas, Diener, Yvonne, Jost, Edgar, Morin-Kensicki, Elizabeth, Goecke, Tamme W, Bosio, Andreas, Rath, Björn, Brümmendorf, Tim H, Bissels, Ute, Wagner, Wolfgang

“…Hematopoietic regeneration after high dose chemotherapy necessitates activation of the stem cell pool. There is evidence that serum taken after chemotherapy…”
Get full text

Impaired Overall Survival in Young Patients With Acute Myeloid Leukemia and Variants in Genes Predisposing for Myeloid Malignancies by Kirschner, Martin, Rolles, Benjamin, Crysandt, Martina, Röllig, Christoph, Stölzel, Friedrich, Kramer, Michael, Bornhäuser, Martin, Serve, Hubert, Platzbecker, Uwe, Müller‐Tidow, Carsten, Kricheldorf, Kim, Vieri, Margherita, Begemann, Matthias, Maurer, Angela, Wlodarski, Marcin W., Sahoo, Sushree S., Brümmendorf, Tim H., Jost, Edgar, Beier, Fabian

Get full text

Abcg2 overexpression represents a novel mechanism for acquired resistance to the multi-kinase inhibitor Danusertib in BCR-ABL-positive cells in vitro by Balabanov, Stefan, Gontarewicz, Artur, Keller, Gunhild, Raddrizzani, Laura, Braig, Melanie, Bosotti, Roberta, Moll, Jürgen, Jost, Edgar, Barett, Christine, Rohe, Imke, Bokemeyer, Carsten, Holyoake, Tessa L, Brümmendorf, Tim H

“…The success of Imatinib (IM) therapy in chronic myeloid leukemia (CML) is compromised by the development of IM resistance and by a limited IM effect on…”
Get full text

Novel homozygous nonsense mutation in the P5′N‐1 coding gene as an alternative cause for hereditary anemia with basophilic stippling by Kirschner, Martin, Heinen, Inga Rebecca, Koschmieder, Steffen, Manco, Licinio, Bento, Celeste, Eggermann, Thomas, Kurth, Ingo, Jost, Edgar, Brümmendorf, Tim H., Fuchs, Roland

“…Hereditary pyrimidine 5‐nucleotidase (P5′N‐1) deficiency is a very rare disorder. Here, we describe a new mutation in a Turkish family. Although functional…”
Get full text

A three-gene expression-based risk score can refine the European LeukemiaNet AML classification by Wilop, Stefan, Chou, Wen-Chien, Jost, Edgar, Crysandt, Martina, Panse, Jens, Chuang, Ming-Kai, Brümmendorf, Tim H, Wagner, Wolfgang, Tien, Hwei-Fang, Kharabi Masouleh, Behzad

“…Risk stratification based on cytogenetics of acute myeloid leukemia (AML) remains imprecise. The introduction of novel genetic and epigenetic markers has…”
Get full text

MicroRNA expression profiles of serum from patients before and after chemotherapy by Diener, Yvonne, Walenda, Thomas, Jost, Edgar, Brümmendorf, Tim H., Bosio, Andreas, Wagner, Wolfgang, Bissels, Ute

“…Recovery of the blood and immune system after chemotherapy requires proliferation of hematopoietic stem and progenitor cells (HPSCs). It has been shown that…”
Get full text