Search Results - "Joslyn, G"

Genome screen for QTLs contributing to normal variation in bone mineral density and osteoporosis by KOLLER, D. L, ECONS, M. J, PEACOCK, M, JOHNSTON, C. C, FOROUD, T, MORIN, P. A, CHRISTIAN, J. C, HUI, S. L, PARRY, P, CURRAN, M. E, RODRIGUEZ, L. A, CONNEALLY, P. M, JOSLYN, G

“…A major determinant of the risk for osteoporosis is peak bone mineral density (BMD), which is largely determined by genetic factors. We recently reported…”
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Linkage of a QTL Contributing to Normal Variation in Bone Mineral Density to Chromosome 11q12–13 by Koller, D. L., Rodriguez, L. A., Christian, J. C., Slemenda, C. W., Econs, M. J., Hui, S. L., Morin, P., Conneally, P. M., Joslyn, G., Curran, M. E., Peacock, M., Johnston, C. C., Foroud, T.

“…Osteoporosis is a leading public health problem that is responsible for substantial morbidity and mortality. A major determinant of the risk for osteoporosis…”
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A Quantitative Trait Locus for Normal Variation in Forearm Bone Mineral Density in Pedigreed Baboons Maps to the Ortholog of Human Chromosome 11q by Havill, L. M., Mahaney, M. C., Cox, L. A., Morin, P. A., Joslyn, G., Rogers, J.

“…Baboons share many anatomical, physiological, and developmental characteristics with humans that make them excellent models for human bone maintenance and…”
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Dimer Formation by an N-Terminal Coiled Coil in the APC Protein by Joslyn, Geoff, Richardson, Diane S., White, Ray, Alber, Tom

“…Mutations in the human APC gene are associated with an inherited predisposition to colon cancer. APC codes for polypeptides of ≈2800 amino acids, with sequence…”
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A CA repeat 30-70 KB downstream from the adenomatous polyposis coli (APC) gene by Spirio, L, Joslyn, G, Nelson, L, Leppert, M, White, R

“…Images…”
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Mutational analysis of patients with adenomatous polyposis : identical inactivating mutations in unrelated individuals by GRODEN, J, GELBERT, L, LEPPERT, M, WHITE, R, THLIVERIS, A, NELSON, L, ROBERTSON, M, JOSLYN, G, SAMOWITZ, W, SPIRIO, L, CARLSON, M, BURT, R

“…Samples of constitutional DNA from 60 unrelated patients with adenomatous polyposis coli (APC) were examined for mutations in the APC gene. Five inactivating…”
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Genome Screen for QTLs Contributing to Normal Variation in Bone Mineral Density and Osteoporosis by Koller, D. L., Econs, M. J., Morin, P. A., Christian, J. C., Hui, S. L., Parry, P., Curran, M. E., Rodriguez, L. A., Conneally, P. M., Joslyn, G., Peacock, M., Johnston, C. C., Foroud, T.

“…A major determinant of the risk for osteoporosis is peak bone mineral density (BMD), which is largely determined by genetic factors. We recently reported…”
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Long-range physical map and deletion characterization of the 1100-kb NotI restriction fragment harboring the APC gene by Thliveris, A, Albertsen, H, Tuohy, T, Carlson, M, Groden, J, Joslyn, G, Gelbert, L, Samowitz, W, Spirio, L, White, R

“…Adenomatous polyposis coli (APC) is an autosomal dominant inherited disorder manifested by early onset of numerous adenomatous polyps and an increased…”
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Cytogenetic analysis of a segment of the Y chromosome of Drosophila melanogaster by Hardy, R.W, Lindsley, D.L, Livak, K.J, Lewis, B, Siversten, A.L, Joslyn, G.L, Edwards, J, Bonaccorsi, S

“…Males carrying a large deficiency in the long arm of the Y chromosome known to delete the fertility gene kl-2 are sterile and exhibit a complex phenotype: (1)…”
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A CA repeat 30–70 Kb downstream from the adenomatous polyposis coli (APC) gene by Spirio, L., Nelson, L., Joslyn, G., Leppert, M., White, R.

“…Nucleic Acids Research, 19, p. 6348 (1991) Please note that the nucleotide sequence of one of the primers, LNS-CA2, was published incorrectly in this paper…”
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A Susceptibility Locus for Migraine with Aura, on Chromosome 4q24 by Wessman, Maija, Kallela, Mikko, Kaunisto, Mari A., Marttila, Pia, Sobel, Eric, Hartiala, Jaana, Oswell, Greg, Leal, Suzanne M., Papp, Jeanette C., Hämäläinen, Eija, Broas, Petra, Joslyn, Geoffrey, Hovatta, Iiris, Hiekkalinna, Tero, Kaprio, Jaakko, Ott, Jürg, Cantor, Rita M., Zwart, John-Anker, Ilmavirta, Matti, Havanka, Hannele, Färkkilä, Markus, Peltonen, Leena, Palotie, Aarno

“…Migraine is a complex neurovascular disorder with substantial evidence supporting a genetic contribution. Prior attempts to localize susceptibility loci for…”
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Genomewide Search for Type 2 Diabetes Susceptibility Genes in Four American Populations by Ehm, Margaret Gelder, Karnoub, Maha C., Sakul, Hakan, Gottschalk, Kirby, Holt, Donald C., Weber, James L., Vaske, David, Briley, David, Briley, Linda, Kopf, Jan, McMillen, Patrick, Nguyen, Quan, Reisman, Melanie, Lai, Eric H., Joslyn, Geoff, Shepherd, Nancy S., Bell, Callum, Wagner, Michael J., Burns, Daniel K.

“…Type 2 diabetes is a serious, genetically influenced disease for which no fully effective treatments are available. Identification of biochemical or regulatory…”
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Alleles of the APC gene: an attenuated form of familial polyposis by Spirio, L, Olschwang, S, Groden, J, Robertson, M, Samowitz, W, Joslyn, G, Gelbert, L, Thliveris, A, Carlson, M, Otterud, B

“…An attenuated form of familial adenomatous polyposis coli, AAPC, causes relatively few colonic polyps, but still carries a significant risk of colon cancer…”
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A Genetic Linkage Map of the Baboon (Papio hamadryas) Genome Based on Human Microsatellite Polymorphisms by Rogers, Jeffrey, Mahaney, Michael C., Witte, Shelly M., Nair, Shalini, Newman, Deborah, Wedel, Steven, Rodriguez, Lawrence A., Rice, Karen S., Slifer, Susan H., Perelygin, Andrey, Slifer, Michael, Palladino-Negro, Paula, Newman, Timothy, Chambers, Karen, Joslyn, Geoff, Parry, Pauline, Morin, Phillip A.

“…A first-generation genetic linkage map of the baboon (Papio hamadryas) genome was developed for use in biomedical and evolutionary genetics. Pedigreed baboons…”
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Identification and characterization of the familial adenomatous polyposis coli gene by Groden, J, Thliveris, A, Samowitz, W, Carlson, M, Gelbert, L, Albertsen, H, Joslyn, G, Stevens, J, Spirio, L, Robertson, M

“…DNA from 61 unrelated patients with adenomatous polyposis coli (APC) was examined for mutations in three genes (DP1, SRP19, and DP2.5) located within a 100 kb…”
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Genome Screen for Quantitative Trait Loci Underlying Normal Variation in Femoral Structure by Koller, Daniel L., Liu, Guangda, Econs, Michael J., Hui, Siu L., Morin, Phillip A., Joslyn, Geoff, Rodriguez, Lawrence A., Conneally, P. Michael, Christian, Joe C., Johnston, C. Conrad, Foroud, Tatiana, Peacock, Munro

“…Femoral structure contributes to bone strength at the proximal femur and predicts hip fracture risk independently of bone mass. Quantitative components of…”
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Association of the G‐174C Variant in the Interleukin‐6 Promoter Region With Bone Loss and Fracture Risk in Older Women by Moffett, Susan P, Zmuda, Joseph M, Cauley, Jane A, Stone, Katie L, Nevitt, Michael C, Ensrud, Kristine E, Hillier, Teresa A, Hochberg, Marc C, Joslyn, Geoff, Morin, Phillip, Cummings, Steven R

“…We analyzed the association between the IL‐6 G‐174C polymorphism and osteoporosis phenotypes in 3376 older women. Women with the C/C genotype had a…”
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Identification of deletion mutations and three new genes at the familial polyposis locus by Joslyn, G, Carlson, M, Thliveris, A, Albertsen, H, Gelbert, L, Samowitz, W, Groden, J, Stevens, J, Spirio, L, Robertson, M

“…Small (100-260 kb), nested deletions were characterized in DNA from two unrelated patients with familial adenomatous polyposis coli (APC). Three candidate…”
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Identification of a Gene Located at Chromosome 5q21 That is Mutated in Colorectal Cancers by Kinzler, Kenneth W., Nilbert, Mef C., Vogelstein, Bert, Bryan, Tracy M., Levy, Daniel B., Smith, Kelly J., Preisinger, Antonette C., Hamilton, Stanley R., Hedge, Phil, Markham, Alex, Carlson, Mary, Joslyn, Geoff, Groden, Joanna, White, Ray, Miki, Yoshoi, Miyoshi, Yasuo, Nishisho, Isamu, Nakamura, Yusuke

“…Recent studies have suggested the existence of a tumor suppressor gene located at chromosome region 5q21. DNA probes from this region were used to study a…”
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Response of colon cancer cell lines to the introduction of APC, a colon-specific tumor suppressor gene by GRODEN, J, JOSLYN, G, WHITE, R, SAMOWITZ, W, JONES, D, NITAI BHATTACHARYYA, SPIRIO, L, THLIVERIS, A, ROBERTSON, M, EGAN, S, MEUTH, M

“…The APC gene, mutations in which are responsible for the inherited colon cancer syndrome adenomatous polyposis coli (APC), is described as a tumor suppressor…”
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