Search Results - "Josleyn, Nicole"

Convalescent plasma anti-SARS-CoV-2 spike protein ectodomain and receptor-binding domain IgG correlate with virus neutralization by Salazar, Eric, Kuchipudi, Suresh V, Christensen, Paul A, Eagar, Todd, Yi, Xin, Zhao, Picheng, Jin, Zhicheng, Long, S Wesley, Olsen, Randall J, Chen, Jian, Castillo, Brian, Leveque, Christopher, Towers, Dalton, Lavinder, Jason, Gollihar, Jimmy, Cardona, Jose, Ippolito, Gregory, Nissly, Ruth, Bird, Ian, Greenawalt, Denver, Rossi, Randall M, Gontu, Abhinay, Srinivasan, Sreenidhi, Poojary, Indira, Cattadori, Isabella M, Hudson, Peter J, Josleyn, Nicole M, Prugar, Laura, Huie, Kathleen, Herbert, Andrew, Bernard, David W, Dye, John M, Kapur, Vivek, Musser, James M

“…The newly emerged severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) highlights the urgent need for assays that detect protective levels of…”
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Characterization of an Anti-Ebola Virus Hyperimmune Globulin Derived From Convalescent Plasma by Ciencewicki, Jonathan M, Herbert, Andrew S, Storm, Nadia, Josleyn, Nicole M, Huie, Kathleen E, McKay, Lindsay G A, Griffiths, Anthony, Dye, John M, Willis, Todd, Arora, Vikram

“…Convalescent plasma has been used to treat many viral diseases including Ebola. The manufacture of a purified anti-Ebola virus (EBOV) intravenous…”
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Development of an antibody cocktail for treatment of Sudan virus infection by Herbert, Andrew S., Froude, Jeffery W., Ortiz, Ramon A., Kuehne, Ana I., Dorosky, Danielle E., Bakken, Russell R., Zak, Samantha E., Josleyn, Nicole M., Musiychuk, Konstantin, Jones, R. Mark, Green, Brian, Streatfield, Stephen J., Wec, Anna Z., Bohorova, Natasha, Bohorov, Ognian, Kim, Do H., Pauly, Michael H., Velasco, Jesus, Whaley, Kevin J., Stonier, Spencer W., Bornholdt, Zachary A., Chandran, Kartik, Zeitlin, Larry, Sampey, Darryl, Yusibov, Vidadi, Dye, John M.

“…Antibody-based therapies are a promising treatment option for managing ebolavirus infections. Several Ebola virus (EBOV)-specific and, more recently,…”
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Monkeypox virus infection of rhesus macaques induces massive expansion of natural killer cells but suppresses natural killer cell functions by Song, Haifeng, Josleyn, Nicole, Janosko, Krisztina, Skinner, Jeff, Reeves, R Keith, Cohen, Melanie, Jett, Catherine, Johnson, Reed, Blaney, Joseph E, Bollinger, Laura, Jennings, Gerald, Jahrling, Peter B

“…Natural killer (NK) cells play critical roles in innate immunity and in bridging innate and adaptive immune responses against viral infection. However, the…”
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Inactivated rabies-based Lassa fever virus vaccine candidate LASSARAB protects nonhuman primates from lethal disease by Scher, Gabrielle, Yankowski, Catherine, Kurup, Drishya, Josleyn, Nicole M., Wilkinson, Eric R., Wells, Jay, Steffens, Jesse, Lynn, Ginger, Vantongeren, Sean, Zeng, Xiankun, Twenhafel, Nancy, Cashman, Kathleen A., Schnell, Matthias J.

“…Lassa fever virus (LASV), a member of the Arenavirus family, is the etiological agent of Lassa fever, a severe hemorrhagic disease that causes considerable…”
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Characterization of Yellow Fever Virus Infection of Human and Non-human Primate Antigen Presenting Cells and Their Interaction with CD4+ T Cells by Cong, Yu, McArthur, Monica A, Cohen, Melanie, Jahrling, Peter B, Janosko, Krisztina B, Josleyn, Nicole, Kang, Kai, Zhang, Tengfei, Holbrook, Michael R

“…Humans infected with yellow fever virus (YFV), a mosquito-borne flavivirus, can develop illness ranging from a mild febrile disease to hemorrhagic fever and…”
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Acute Late-Stage Myocarditis in the Crab-Eating Macaque Model of Hemorrhagic Smallpox by Johnson, Reed F, Keith, Lauren A, Cooper, Timothy K, Yellayi, Srikanth, Josleyn, Nicole M, Janosko, Krisztina B, Pettitt, James D, Thomasson, David, Hagen, Katie R, Gross, Robin, Bernbaum, John G, Douglas, Debbie, Solomon, Jeffrey, Martinez, Mark, Cooper, Kurt, St Claire, Marisa, Ragland, Danny R, Jahrling, Peter B, Kuhn, Jens H, Arai, Andrew E

“…Hemorrhagic smallpox, caused by variola virus (VARV), was a rare but nearly 100% lethal human disease manifestation. Hemorrhagic smallpox is frequently…”
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Poxvirus antigen staining of immune cells as a biomarker to predict disease outcome in monkeypox and cowpox virus infection in non-human primates by Song, Haifeng, Janosko, Krisztina, Johnson, Reed F, Qin, Jing, Josleyn, Nicole, Jett, Catherine, Byrum, Russell, St Claire, Marisa, Dyall, Julie, Blaney, Joseph E, Jennings, Gerald, Jahrling, Peter B

“…Infection of non-human primates (NHPs) such as rhesus and cynomolgus macaques with monkeypox virus (MPXV) or cowpox virus (CPXV) serve as models to study…”
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An in vitro/ex vivo human lung infection model for studying the macrophage innate immune response to Ebola virus Kikwit by Josleyn, Nicole M., Kuehne, Ana, O’Brien, Cecilia, Brannan, Jennifer, Edwards, Darin, Parkhill, Robert, Dye, John M.

“…Abstract Ebola virus causes a severe and often fatal hemorrhagic fever in people, for which no approved vaccines or therapeutics are available. Disease…”
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Cytokine and chemokine profiles in a human respiratory disease model of Ebola virus by O’Brien, Cecilia, Brannan, Jennifer, Kuehne, Ana, Josleyn, Nicole M., Parkhill, Robert, Edwards, Darin, Dye, John M.

“…Abstract Category A agents, such as Ebola virus, pose a great risk to national security because of high rates of transmission and mortality and the gravity of…”
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Immune correlates for VEEV replicon vaccine protection against Ebolavirus by Stonier, Spencer W, James, Rebekah M, Josleyn, Nicole M, Bakken, Russell R, Dye, John M

“…Abstract The progress of filovirus vaccines has advanced greatly due in part to the urgent need to develop countermeasures for the unprecedented Ebolavirus…”
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Pro-inflammatory cytokine production by activated monocytes and macrophages in response to cowpox virus infection in cynomologus macaques (VIR9P.1144) by Janosko, Krisztina, Cohen, Melanie, Josleyn, Nicole, Zhang, Tengfei, Cong, Yu, Jahrling, Peter, Johnson, Reed

“…Abstract Monocytes and macrophages play pivotal roles in host defense against microbial and viral pathogens through production of inflammatory and cytotoxic…”
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Evaluation of bone marrow in cowpox virus infection in cynomolgus macaques (VIR1P.1127) by Josleyn, Nicole, Yellayi, Srikanth, Martinez, Mark, Janosko, Krisztina, Adams, Ricky, Burdette, Tracey, Cohen, Melanie, Zhang, Tengfei, Jahrling, Peter, Johnson, Reed

“…Abstract Evaluation of countermeasures against variola virus, the causative agent of smallpox, must be performed through extrapolation from suitable animal…”
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Development of a Flow Cytometry Assay to Study Monkeypox Virus Infection and Immune Response Regulation in Nonhuman Primates by Josleyn, Nicole Marie

“…Monkeypox virus (MPXV) is divided into two clades, Congo Basin and West African. Congo Basin MPXV infection is associated with severe symptoms and fatality of…”
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Characterization of Yellow Fever Virus Infection of Human and Non-human Primate Antigen Presenting Cells and Their Interaction with CD4.sup.+ T Cells by Cong, Yu, McArthur, Monica A, Cohen, Melanie, Jahrling, Peter B, Janosko, Krisztina B, Josleyn, Nicole, Kang, Kai, Zhang, Tengfei, Holbrook, Michael R

“…Humans infected with yellow fever virus (YFV), a mosquito-borne flavivirus, can develop illness ranging from a mild febrile disease to hemorrhagic fever and…”
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Characterizing monkeypox virus specific CD8+ T cell epitopes in rhesus macaques by Song, Haifeng, Sidney, John, Wiseman, Roger W, Josleyn, Nicole, Cohen, Melanie, Blaney, Joseph E, Jahrling, Peter B, Sette, Alessandro

“…Abstract To characterize T cell epitopes in monkeypox virus (MPXV) infected rhesus macaques, we utilized IFN γ Elispot assay to screen 400 predicted peptides…”
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Monkeypox virus infection of rhesus macaques induces massive expansion of NK cells, but suppresses NK cell function (P4369) by Song, Haifeng, Josleyn, Nicole, Janosko, Krisztina, Skinner, Jeff, Reeves, R. Keith, Cohen, Melanie, Blaney, Joe, Jahrling, Peter

“…Abstract In the current study of MPXV infection in rhesus macaques, we analyzed the NK cell responses in absolute cell numbers, cell proliferation, chemokine…”
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Monkeypox Virus Infection of Rhesus Macaques Induces Massive Expansion of Natural Killer Cells but Suppresses Natural Killer Cell Functions by Song, Haifeng, Josleyn, Nicole, Janosko, Krisztina, Skinner, Jeff, Reeves, R. Keith, Cohen, Melanie, Jett, Catherine, Johnson, Reed, Blaney, Joseph E., Bollinger, Laura, Jennings, Gerald, Jahrling, Peter B.

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Safety Precautions and Operating Procedures in an (A)BSL-4 Laboratory: 2. General Practices by Mazur, Steven, Holbrook, Michael R, Burdette, Tracey, Joselyn, Nicole, Barr, Jason, Pusl, Daniela, Bollinger, Laura, Coe, Linda, Jahrling, Peter B, Lackemeyer, Matthew G, Wada, Jiro, Kuhn, Jens H, Janosko, Krisztina

“…Work in a biosafety level 4 (BSL-4) containment laboratory requires time and great attention to detail. The same work that is done in a BSL-2 laboratory with…”
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Safety Precautions and Operating Procedures in an (A)BSL-4 Laboratory: 2. General Practices by Mazur, Steven, Holbrook, Michael R., Burdette, Tracey, Josleyn, Nicole, Barr, Jason, Pusl, Daniela, Bollinger, Laura, Coe, Linda, Jahrling, Peter B., Lackemeyer, Matthew G., Wada, Jiro, Kuhn, Jens H., Janosko, Krisztina

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