Search Results - "Joshua"

A critical period for second language acquisition: Evidence from 2/3 million English speakers by Hartshorne, Joshua K., Tenenbaum, Joshua B., Pinker, Steven

“…Children learn language more easily than adults, though when and why this ability declines have been obscure for both empirical reasons (underpowered studies)…”
Get full text

Sex as a Biological Variable in Atherosclerosis by Man, Joshua J., Beckman, Joshua A., Jaffe, Iris Z.

“…Atherosclerosis is a chronic inflammatory vascular disease and the predominant cause of heart attack and ischemic stroke. Despite the well-known sexual…”
Get full text

Calorie Restriction and SIRT3 Trigger Global Reprogramming of the Mitochondrial Protein Acetylome by Hebert, Alexander S., Dittenhafer-Reed, Kristin E., Yu, Wei, Bailey, Derek J., Selen, Ebru Selin, Boersma, Melissa D., Carson, Joshua J., Tonelli, Marco, Balloon, Allison J., Higbee, Alan J., Westphall, Michael S., Pagliarini, David J., Prolla, Tomas A., Assadi-Porter, Fariba, Roy, Sushmita, Denu, John M., Coon, Joshua J.

“…Calorie restriction (CR) extends life span in diverse species. Mitochondria play a key role in CR adaptation; however, the molecular details remain elusive. We…”
Get full text

Quantitative Imaging of Gut Microbiota Spatial Organization by Earle, Kristen A., Billings, Gabriel, Sigal, Michael, Lichtman, Joshua S., Hansson, Gunnar C., Elias, Joshua E., Amieva, Manuel R., Huang, Kerwyn Casey, Sonnenburg, Justin L.

“…Genomic technologies have significantly advanced our understanding of the composition and diversity of host-associated microbial populations. However, their…”
Get full text

dynesty: a dynamic nested sampling package for estimating Bayesian posteriors and evidences by Speagle, Joshua S

“…ABSTRACT We present dynesty, a public, open-source, python package to estimate Bayesian posteriors and evidences (marginal likelihoods) using the dynamic…”
Get full text

Amivantamab in EGFR Exon 20 Insertion-Mutated Non-Small-Cell Lung Cancer Progressing on Platinum Chemotherapy: Initial Results From the CHRYSALIS Phase I Study by Park, Keunchil, Haura, Eric B, Leighl, Natasha B, Mitchell, Paul, Shu, Catherine A, Girard, Nicolas, Viteri, Santiago, Han, Ji-Youn, Kim, Sang-We, Lee, Chee Khoon, Sabari, Joshua K, Spira, Alexander I, Yang, Tsung-Ying, Kim, Dong-Wan, Lee, Ki Hyeong, Sanborn, Rachel E, Trigo, José, Goto, Koichi, Lee, Jong-Seok, Yang, James Chih-Hsin, Govindan, Ramaswamy, Bauml, Joshua M, Garrido, Pilar, Krebs, Matthew G, Reckamp, Karen L, Xie, John, Curtin, Joshua C, Haddish-Berhane, Nahor, Roshak, Amy, Millington, Dawn, Lorenzini, Patricia, Thayu, Meena, Knoblauch, Roland E, Cho, Byoung Chul

“…Non-small-cell lung cancer (NSCLC) with epidermal growth factor receptor ( ) exon 20 insertion (Exon20ins) mutations exhibits inherent resistance to approved…”
Get full text

The Faintest Dwarf Galaxies by Simon, Joshua D

“…The lowest luminosity ( L ) Milky Way satellite galaxies represent the extreme lower limit of the galaxy luminosity function. These ultra-faint dwarfs are the…”
Get full text

Pupil Size as a Window on Neural Substrates of Cognition by Joshi, Siddhartha, Gold, Joshua I.

“…Cognitively driven pupil modulations reflect certain underlying brain functions. What do these reflections tell us? Here, we review findings that have…”
Get full text

CIDR: Ultrafast and accurate clustering through imputation for single-cell RNA-seq data by Lin, Peijie, Troup, Michael, Ho, Joshua W K

“…Most existing dimensionality reduction and clustering packages for single-cell RNA-seq (scRNA-seq) data deal with dropouts by heavy modeling and computational…”
Get full text

Seasonal cycling in the gut microbiome of the Hadza hunter-gatherers of Tanzania by Smits, Samuel A., Leach, Jeff, Sonnenburg, Erica D., Gonzalez, Carlos G., Lichtman, Joshua S., Reid, Gregor, Knight, Rob, Manjurano, Alphaxard, Changalucha, John, Elias, Joshua E., Dominguez-Bello, Maria Gloria, Sonnenburg, Justin L.

“…Although humans have cospeciated with their gut-resident microbes, it is difficult to infer features of our ancestral microbiome. Here, we examine the…”
Get full text

Fatigue and cognitive impairment in Post-COVID-19 Syndrome: A systematic review and meta-analysis by Ceban, Felicia, Ling, Susan, Lui, Leanna M.W., Lee, Yena, Gill, Hartej, Teopiz, Kayla M., Rodrigues, Nelson B., Subramaniapillai, Mehala, Di Vincenzo, Joshua D., Cao, Bing, Lin, Kangguang, Mansur, Rodrigo B., Ho, Roger C., Rosenblat, Joshua D., Miskowiak, Kamilla W., Vinberg, Maj, Maletic, Vladimir, McIntyre, Roger S.

“…•Fatigue and cognitive impairment are amongst the most common and debilitating symptoms of post-COVID-19 syndrome.•Approximately 1 in 3 individuals experienced…”
Get full text

How behavioral science can help conservation by Cinner, Joshua

“…Leveraging cognitive biases and social influence can make conservation efforts more effective Most conservation initiatives require changes in human behavior…”
Get full text

The secret lives of experiments: Methods reporting in the fMRI literature by Carp, Joshua

“…Replication of research findings is critical to the progress of scientific understanding. Accordingly, most scientific journals require authors to report…”
Get full text

Interactions between Biomolecules and Zwitterionic Moieties: A Review by Erfani, Amir, Seaberg, Joshua, Aichele, Clint Philip, Ramsey, Joshua D

“…Throughout the past decade, zwitterionic moieties have gained attention as constituents of biocompatible materials for exhibiting superhydrophilic properties…”
Get full text

Structural basis of nucleosome-dependent cGAS inhibition by Boyer, Joshua A, Spangler, Cathy J, Strauss, Joshua D, Cesmat, Andrew P, Liu, Pengda, McGinty, Robert K, Zhang, Qi

“…Cyclic guanosine monophosphate (GMP)-adenosine monophosphate (AMP) synthase (cGAS) recognizes cytosolic foreign or damaged DNA to activate the innate immune…”
Get full text

jsPsych: A JavaScript library for creating behavioral experiments in a Web browser by de Leeuw, Joshua R.

“…Online experiments are growing in popularity, and the increasing sophistication of Web technology has made it possible to run complex behavioral experiments…”
Get full text

Single-Cell Profiles of Retinal Ganglion Cells Differing in Resilience to Injury Reveal Neuroprotective Genes by Tran, Nicholas M., Shekhar, Karthik, Whitney, Irene E., Jacobi, Anne, Benhar, Inbal, Hong, Guosong, Yan, Wenjun, Adiconis, Xian, Arnold, McKinzie E., Lee, Jung Min, Levin, Joshua Z., Lin, Dingchang, Wang, Chen, Lieber, Charles M., Regev, Aviv, He, Zhigang, Sanes, Joshua R.

“…Neuronal types in the central nervous system differ dramatically in their resilience to injury or other insults. Here we studied the selective resilience of…”
Get full text

Treatment and Outcome of Hemorrhagic Transformation After Intravenous Alteplase in Acute Ischemic Stroke: A Scientific Statement for Healthcare Professionals From the American Heart Association/American Stroke Association by Yaghi, Shadi, Willey, Joshua Z, Cucchiara, Brett, Goldstein, Joshua N, Gonzales, Nicole R, Khatri, Pooja, Kim, Louis J, Mayer, Stephan A, Sheth, Kevin N, Schwamm, Lee H

“…PURPOSE—Symptomatic intracranial hemorrhage (sICH) is the most feared complication of intravenous thrombolytic therapy in acute ischemic stroke. Treatment of…”
Get full text

Sporadic autism exomes reveal a highly interconnected protein network of de novo mutations by O’Roak, Brian J., Vives, Laura, Girirajan, Santhosh, Karakoc, Emre, Krumm, Niklas, Coe, Bradley P., Levy, Roie, Ko, Arthur, Lee, Choli, Smith, Joshua D., Turner, Emily H., Stanaway, Ian B., Vernot, Benjamin, Malig, Maika, Baker, Carl, Reilly, Beau, Akey, Joshua M., Borenstein, Elhanan, Rieder, Mark J., Nickerson, Deborah A., Bernier, Raphael, Shendure, Jay, Eichler, Evan E.

“…Exome sequencing on a large cohort of parent–child trios with sporadic autism spectrum disorders shows that de novo point mutations are mainly paternal in…”
Get full text

Comprehensive Classification of Retinal Bipolar Neurons by Single-Cell Transcriptomics by Shekhar, Karthik, Lapan, Sylvain W., Whitney, Irene E., Tran, Nicholas M., Macosko, Evan Z., Kowalczyk, Monika, Adiconis, Xian, Levin, Joshua Z., Nemesh, James, Goldman, Melissa, McCarroll, Steven A., Cepko, Constance L., Regev, Aviv, Sanes, Joshua R.

“…Patterns of gene expression can be used to characterize and classify neuronal types. It is challenging, however, to generate taxonomies that fulfill the…”
Get full text