Search Results - "Joshi, Tushar"
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Structure-based screening of novel lichen compounds against SARS Coronavirus main protease (Mpro) as potentials inhibitors of COVID-19
Published in Molecular diversity (01-08-2021)“…The outbreak of SARS-CoV-2 and deaths caused by it all over the world have imposed great concern on the scientific community to develop potential drugs to…”
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Health and economic impact of air pollution in the states of India: the Global Burden of Disease Study 2019
Published in The Lancet. Planetary health (01-01-2021)“…The association of air pollution with multiple adverse health outcomes is becoming well established, but its negative economic impact is less well appreciated…”
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Virtual screening of anti-HIV1 compounds against SARS-CoV-2: machine learning modeling, chemoinformatics and molecular dynamics simulation based analysis
Published in Scientific reports (23-11-2020)“…COVID-19 caused by the SARS-CoV-2 is a current global challenge and urgent discovery of potential drugs to combat this pandemic is a need of the hour…”
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The burden of chronic respiratory diseases and their heterogeneity across the states of India: the Global Burden of Disease Study 1990–2016
Published in The Lancet global health (01-12-2018)“…India has 18% of the global population and an increasing burden of chronic respiratory diseases. However, a systematic understanding of the distribution of…”
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Assessment of activity of chalcone compounds as inhibitors of 3-chymotrypsin like protease (3CLPro) of SARS-CoV-2: in silico study
Published in Structural chemistry (01-10-2022)“…The COVID-19 is still pandemic due to emerging of various variant of concern of SARS-CoV2. Hence, it is devastating the world, causing significant economic as…”
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Antimicrobial activity of methanolic extracts of Vernonia cinerea against Xanthomonas oryzae and identification of their compounds using in silico techniques
Published in PloS one (14-06-2021)“…Bacterial Leaf Blight (BLB) disease is an extremely ruinous disease in rice, caused by Xanthomonas oryzae pv. oryzae ( Xoo ). Although various chemicals are…”
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Using Chou’s 5-steps rule to study pharmacophore-based virtual screening of SARS-CoV-2 Mpro inhibitors
Published in Molecular diversity (01-08-2021)“…Recently emerged SARS-CoV-2 is the cause of the ongoing outbreak of COVID-19. It is responsible for the deaths of millions of people and has caused global…”
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8
Finding top performers through email patterns analysis
Published in Journal of information science (01-08-2020)“…In the information economy, individuals’ work performance is closely associated with their digital communication strategies. This study combines social network…”
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In silico screening of chalcone derivatives as promising EGFR-TK inhibitors for the clinical treatment of cancer
Published in 3 Biotech (2024)“…Epidermal growth factor receptor (EGFR) promotes tumorigenic characteristics and activates cancer-associated signaling pathways such as Wnt/-catenin,…”
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Identification of Putative Elicitors From Plant Root Exudates Responsible for PsoR Activation in Plant-Beneficial Pseudomonas spp. by Docking and Molecular Dynamics Simulation Approaches to Decipher Plant-Microbe Interaction
Published in Frontiers in plant science (06-04-2022)“…Plants and rhizobacteria are coexisting since the beginning, but the exact mechanism of communication between them remains enigmatic. The PsoR protein of…”
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Identifying Novel Therapeutics for the Resistant Mutant “F533L” in PBP3 of Pseudomonas aeruginosa Using ML Techniques
Published in ACS omega (02-07-2024)“…Pseudomonas aeruginosa (P. aeruginosa) is a highly infectious and antibiotic-resistant bacterium, which causes acute and chronic nosocomial infections. P…”
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Integrated Machine Learning and Chemoinformatics-Based Screening of Mycotic Compounds against Kinesin Spindle ProteinEg5 for Lung Cancer Therapy
Published in Molecules (Basel, Switzerland) (02-03-2022)“…Among the various types of cancer, lung cancer is the second most-diagnosed cancer worldwide. The kinesin spindle protein, Eg5, is a vital protein behind…”
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The impact of air pollution on deaths, disease burden, and life expectancy across the states of India: the Global Burden of Disease Study 2017
Published in The Lancet. Planetary health (01-01-2019)“…Air pollution is a major planetary health risk, with India estimated to have some of the worst levels globally. To inform action at subnational levels in…”
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Formulation and evaluation of SGLT2 inhibitory effect of a polyherbal mixture inspired from Ayurvedic system of medicine
Published in Journal of Traditional and Complementary Medicine (01-09-2022)“…Background and aim: The ingredients viz., Artemisia roxburghiana, Cissampelos pareira, Stephania glabra, Drimia indica, Roylea cinerea, Tinospora sinensis and…”
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Identification of Zinc-Binding Inhibitors of Matrix Metalloproteinase-9 to Prevent Cancer Through Deep Learning and Molecular Dynamics Simulation Approach
Published in Frontiers in molecular biosciences (31-03-2022)“…The overexpression of matrix metalloproteinase-9 (MMP-9) is associated with tumor development and angiogenesis, and hence, it has been considered an attractive…”
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Heavy Metal Accumulation in Fruits and Vegetables and Human Health Risk Assessment: Findings From Maharashtra, India
Published in Environmental health insights (2022)“…background: Vegetables are consumed enormously by humans all over the world. Consumption of contaminated fruits and vegetables is the most likely route of…”
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Human Health Risk Assessment due to Heavy Metals in Ground and Surface Water and Association of Diseases With Drinking Water Sources: A Study From Maharashtra, India
Published in Environmental health insights (01-01-2022)“…Background: Contamination of freshwater sources can be caused by both anthropogenic and natural processes. According to Central Pollution Control Board,…”
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Gender differences in inflation expectations: Recent evidence from India
Published in Administrative sciences (01-02-2023)“…This study investigates gender disparities in inflation expectations in India using data from the Reserve Bank of India's Households' Inflation Expectations…”
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In silico screening of potential antidiabetic phytochemicals from Phyllanthus emblica against therapeutic targets of type 2 diabetes
Published in Journal of ethnopharmacology (10-02-2020)“…Phyllanthus emblica Linn. (Syn. Emblica officinalis Gaertn.), has been used to cure many ailments of human beings. Literature survey demonstrates that it has…”
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Molecular docking and molecular dynamics simulation approach to screen natural compounds for inhibition of Xanthomonas oryzae pv. Oryzae by targeting peptide deformylase
Published in Journal of biomolecular structure & dynamics (11-02-2021)“…Xanthomonas oryzae pv. Oryzae (Xoo) causes bacterial leaf blight (BLB) of rice which results in a huge loss in production. Many chemicals are used to control…”
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